Immunization with recombinant DcaP-like protein and AbOmpA revealed protections against sepsis infection of multi-drug resistant Acinetobacter baumannii ST2Pas in a C57BL/6 mouse model DOI Creative Commons

Sepideh Fereshteh,

Soheila Ajdary, Amin Sepehr

и другие.

Microbial Pathogenesis, Год журнала: 2022, Номер 174, С. 105882 - 105882

Опубликована: Ноя. 17, 2022

Язык: Английский

Review of current perspectives and future outlook on bacterial disease prevention through vaccination in Asian seabass (Lates calcarifer) DOI
Nguyen Giang Thu Lan, Ha Thanh Dong, Andrew P. Shinn

и другие.

Journal of Fish Diseases, Год журнала: 2024, Номер 47(8)

Опубликована: Май 26, 2024

Asian seabass, Lates calcarifer, is an important aquatic species in mariculture. Intensive farming of this has faced episodes bacterial diseases, including those due to vibriosis, scale drop, and muscle necrosis disease, big belly photobacteriosis, columnaris, streptococcosis, aeromoniasis, tenacibaculosis. Vaccination one the most efficient, non-antibiotic, eco-friendly strategies for protecting fish against contributing aquaculture expansion ensuring food security. As now, although numerous vaccines have undergone laboratory research, only commercially available inactivated vaccine, suitable both immersion injection administration, accessible preventing Streptococcus iniae. Several key challenges developing seabass must be addressed, such as current limited understanding immunological responses vaccines, costs associated with vaccine production, forms, routes application, how increase adoption by farmers. The future development industry, therefore, discussed these critical issues mind. focus on improving our immunity, maternal immunocompetence, immune post-vaccination, well tools assess effectiveness. need alignment state-of-the-art technologies employed human terrestrial animal healthcare also discussed. This review discusses necessity providing locally-produced autogenous especially oral benefit small-scale farmers, potential benefits that might extended through changes husbandry practices vaccination broodstock earlier life stages their off-spring.

Язык: Английский

Процитировано

2

Sex is a Crucial Factor in the Immune Response: An Ichthyological Perspective DOI Creative Commons
Marta Caballero‐Huertas,

Marcela Salazar-Moscoso,

Laia Ribas

и другие.

Reviews in Fisheries Science & Aquaculture, Год журнала: 2024, Номер unknown, С. 1 - 21

Опубликована: Авг. 20, 2024

Sex plays a crucial role in shaping the immune response of vertebrates, leading to differing susceptibilities diseases between females and males. This review explores observed sexually dimorphic patterns different pathogenic infections, responses, molecular events. First, compilation historical guidelines for incorporating gender/sex as variable research studies enhance scientific rigor, improve outcomes, promote better health both sexes has been carried out. Following this, study focuses on examining sex-based differences responses across taxa, with an in-depth available fish, particularly regarding prevalence sex-related parasites, viruses, bacteria. Furthermore, benefits considering sexual dimorphism when evaluating fish management aquaculture ecological contexts have discussed. Integrating sex understanding will positively influence welfare, economic impacts, policymaking, more tailored effective treatments.

Язык: Английский

Процитировано

2

Genomic Analysis of Aeromonas salmonicida ssp. salmonicida Isolates Collected During Multiple Clinical Outbreaks Supports Association with a Single Epidemiological Unit DOI Creative Commons
Konrad Wojnarowski, Paulina Cholewińska, Philipp Steinbauer

и другие.

Pathogens, Год журнала: 2024, Номер 13(10), С. 908 - 908

Опубликована: Окт. 17, 2024

Outbreaks of furunculosis cause significant losses in salmonid aquaculture worldwide. With a recent rise antimicrobial resistance, regulatory measures to minimize the use antibiotics animal husbandry, including aquaculture, have increased scrutiny and availability veterinary medical products control this disease production facilities. In such environment, utility autogenous vaccines assist with prevention as veterinary-guided prophylactic measure is high interest producers services alike. However, evolving concepts epidemiological units links need be considered during approval acceptance procedures for application multiple Here, we present results solid-state nanopore sequencing (Oxford Nanopore Technologies, ONT) performed on 54 isolates Aeromonas salmonicida ssp. sampled clinical outbreaks different facilities from Bavaria, Germany, 2017 2020. All analyses (phylogeny, single nucleotide polymorphism 3D protein modeling major immunogenic proteins) support probability that all studied belong same unit. Simultaneously, describe cost/effective method whole genome analysis usage ONT viable strategy study other pathogens field aquatic medicine purpose developing best vaccine candidates applicable establishments.

Язык: Английский

Процитировано

2

Development of autogenous vaccines for farmed European seabass against Aeromonas veronii using zebrafish as a model for efficacy assessment DOI

Maria Smyrli,

Ishrat Zahan Anka,

Olga S. Koutsoni

и другие.

Fish & Shellfish Immunology, Год журнала: 2022, Номер 123, С. 381 - 387

Опубликована: Март 19, 2022

Язык: Английский

Процитировано

9

Immunization with recombinant DcaP-like protein and AbOmpA revealed protections against sepsis infection of multi-drug resistant Acinetobacter baumannii ST2Pas in a C57BL/6 mouse model DOI Creative Commons

Sepideh Fereshteh,

Soheila Ajdary, Amin Sepehr

и другие.

Microbial Pathogenesis, Год журнала: 2022, Номер 174, С. 105882 - 105882

Опубликована: Ноя. 17, 2022

Язык: Английский

Процитировано

8