Genetic improvement of oysters: Current status, challenges, and prospects

Reviews in Aquaculture, Год журнала: 2023, Номер 16(2), С. 796 - 817

Опубликована: Окт. 30, 2023

Abstract Oysters are one of the most commercially important shellfish species and have been cultured for thousands years. Oyster aquaculture supports major industries in many countries. Over last few decades, oyster breeding developed rapidly to meet continually growing demand. Many researchers made significant efforts toward genetic improvement traits oysters. Some strains with fast‐growing, disease‐resistant, stable shell‐colours through selective breeding. hybrid varieties by crossing different geographical populations or cultivated strains. Several hybrids exhibit considerable variation improved productive performance. Additionally, polyploid induction technologies applied industry, which provides a useful tool performance containment stocks. At present, development molecular also great opportunity improvement. These advances quality oysters, brought economic benefits, conducive sustainability production. Nonetheless, there still some limitations obstacles breeding, such as infectious diseases, summer mortality, conservation germplasm resources, environmental contamination, climate change. The present review an overview current status, challenges, prospects

Язык: Английский

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Genes for editing to improve economic traits in aquaculture fish species

Aquaculture and Fisheries, Год журнала: 2024, Номер unknown

Опубликована: Июль 1, 2024

Aquaculture, a critical sector for global food security, faces the challenge of meeting growing demand while protecting wild fish populations. Gene editing, powerful genetic tool, emerges as potential solution. By modifying key genes in fish, it is expected to rapidly enhance growth rate, disease resistance, and other economically important traits, leading increased profitability, sustainability, competitiveness industry. This review navigates complex landscape gene editing aquaculture, exploring successes, challenges, prospects improved productivity, resilience. We provide guidance researchers stakeholders identifying responsible addressing economic, environmental, regulatory, ethical considerations. roadmap paves way future where empowers aquaculture meet needs upholding environmental responsibility.

Язык: Английский

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CRISPR/Cas9 Technology for Enhancing Desirable Traits of Fish Species in Aquaculture

International Journal of Molecular Sciences, Год журнала: 2024, Номер 25(17), С. 9299 - 9299

Опубликована: Авг. 27, 2024

Aquaculture, the world's fastest-growing food production sector, is critical for addressing security concerns because of its potential to deliver high-quality, nutrient-rich supplies by 2050. This review assesses effectiveness CRISPR/Cas9 genome editing technology in enhancing desirable traits fish species, including growth rates, muscle quality, disease resistance, pigmentation, and more. It also focuses on allowing precise targeted modifications DNA improve characteristics. Many studies have reported successful applications CRISPR/Cas9, such as knocking out reproductive genes control reproduction sex determination, feed conversion efficiency, reducing off-target effects. Additionally, this has contributed environmental sustainability nitrogen-rich waste improving nutritional composition fish. However, acceptance modified public consumers hindered regarding perception, ecological impacts, regulatory frameworks. To gain approval consumer confidence, clear communication about process, well data safety considerations genetically fish, are essential. paper discusses these challenges, provides possible solutions, recommends future research integration into sustainable aquaculture practices, focusing responsible management enable creation disease-resistant strains. In conclusion, highlights transformative traits, while considering challenges ethical associated with practices aquaculture.

Язык: Английский

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Unraveling the Disparity of Carbohydrate Utilization in Farmed Fish: Perspectives From Comparative Pancreatic Islet Biology

Reviews in Aquaculture, Год журнала: 2025, Номер 17(3)

Опубликована: Апрель 1, 2025

ABSTRACT The potential benefits of enhancing the capacity for carbohydrate utilization in farmed fish, particularly species with pronounced intolerance, are significant from a number perspectives. In recent decades, multitude research initiatives have focused on elucidating factors that influence as well biological limitations constrain this process. Despite substantial progress achieved thus far, dearth clarity persists regarding associated tolerance among various species. Evidence suggests that, mammals, pancreatic islet tissues teleosts act regulatory valve glucose assimilation and metabolism. However, precise intricacies remain to be fully elucidated subject ongoing endeavors fish objective review is provide comprehensive evaluation extant gaps domain endocrinology, aim identifying potentially impede Furthermore, it incorporates advancements biology physiological functions homeostasis zebrafish model mammalian animals more overview future directions fish. addition, we present prospective avenues inquiry concomitant challenges achieve profound comprehension fundamental mechanisms precipitate intolerance This expected benefit researchers specializing study metabolism

Язык: Английский

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Generation of Eco-Friendly and Disease-Resistant Channel Catfish (Ictalurus punctatus) Harboring the Alligator Cathelicidin Gene via CRISPR/Cas9 Engineering

Engineering, Год журнала: 2024, Номер 39, С. 273 - 286

Опубликована: Фев. 1, 2024

As a precise and versatile tool for genome manipulation, the clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) platform holds promise modifying fish traits of interest. With aim reducing transgene introgression controlling reproduction, upscaled disease resistance reproductive intervention in catfish species have been studied to lower potential environmental risks escapees as transgenic animals. Taking advantage CRISPR/Cas9-mediated system, we succeeded integrating cathelicidin gene (As-Cath) from an alligator (Alligator sinensis) into target luteinizing hormone (lh) locus channel (Ictalurus punctatus) using two delivery systems assisted by double-stranded DNA (dsDNA) single-stranded oligodeoxynucleotides (ssODNs), respectively. In this study, high knock (KI) efficiency (22.38%, 64/286) but low on-target events was achieved ssODN strategy, whereas adopting dsDNA donor template led efficient KI (10.80%, 23/213). The As-Cath instrumental establishing lh knockout (LH–_As-Cath+) line, which displayed heightened reduced fecundity compared with wild-type (WT) sibling fish. Furthermore, administration human chorionic gonadotropin (HCG) hormone-releasing analogue (LHRHa) can restore reproduction line. Overall, replaced then administered therapy gain complete control disease-resistant environmentally sound manner. This strategy not only effectively improves consumer-valued also guards against unwanted introgression, providing breakthrough aquaculture genetics confine prevent establishment or domestic genotypes natural environment.

Язык: Английский

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Effects of Microorganisms in Fish Aquaculture from a Sustainable Approach: A Review

Microorganisms, Год журнала: 2025, Номер 13(3), С. 485 - 485

Опубликована: Фев. 21, 2025

Aquaculture is the fastest-growing food production sector. However, it faces significant challenges, including demand from a growing global population, which estimated to reach 10.4 billion by year 2100, disease outbreaks, environmental impacts, and overuse of antibiotics. To address these issues, sustainable alternatives such as use microorganisms (probiotics, bacteriophages, genetically modified microorganisms) have gained attention. This review examines effects on fish aquaculture, focusing their potential improve growth, health, resistance while reducing impacts. Probiotics, particularly lactic acid bacteria yeasts, been shown enhance immune responses, digestive enzyme activity, nutrient absorption in fish. Bacteriophages offer promising alternative antibiotics for controlling bacterial pathogens, with studies demonstrating efficacy mortality rates infected Additionally, (GMMs) explored ability produce beneficial compounds, enzymes antimicrobial peptides, can health reduce need chemical treatments. Despite potential, challenges regulatory hurdles, public acceptance, risks must be addressed. highlights importance further research optimize aquaculture underscores role promoting practices. By integrating biological tools, industry move towards more environmentally friendly future.

Язык: Английский

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Integration of alligator cathelicidin gene via two CRISPR/Cas9-assisted systems enhances bacterial resistance in blue catfish, Ictalurus furcatus

Aquaculture, Год журнала: 2023, Номер 576, С. 739860 - 739860

Опубликована: Июль 4, 2023

Язык: Английский

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A guide to assess the use of gene editing in aquaculture

Reviews in Aquaculture, Год журнала: 2023, Номер 16(2), С. 775 - 784

Опубликована: Окт. 20, 2023

Abstract Aquaculture creates ‘aquatic foods’ such as fish, shellfish, and seaweeds that are critical for food security. Gene editing using CRISPR‐Cas9 has the potential to transform aquaculture by improving animal welfare, nutritional attributes, farming efficiency, with benefits environmental sustainability. However, gene also poses risks of harm via side effects on other important traits or genetic introgression into wild populations. Public acceptance edited aquatic species will rapidly erode if risk mitigation is ineffective not applied. Here, we review in aquaculture. A general framework risk–benefit analysis proposed, incorporating nine key considerations: impacts, ecological disease mitigation, nature edit, supply chain footprint, human nutrition, ethical business implications impacts local communities. When applied a case‐by‐case basis, help identify how farmed can most enhance production while minimising harms environment, society.

Язык: Английский

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Challenges for the Post-Market Environmental Monitoring in the European Union Imposed by Novel Applications of Genetically Modified and Genome-Edited Organisms

BioTech, Год журнала: 2024, Номер 13(2), С. 14 - 14

Опубликована: Май 15, 2024

Information on the state of environment is important to achieve objectives European Green Deal, including EU's Biodiversity Strategy for 2030. The existing regulatory provisions genetically modified organisms (GMOs) foresee an obligatory post-market environmental monitoring (PMEM) potential adverse effects upon release into environment. So far, GMO activities have focused crops. With advent new genomic techniques (NGT), novel applications are being developed and may be released a range different, non-agricultural environments with implications ecosystems biodiversity. This challenges current concepts requires adaptation programs meet requirements. While incorporation biodiversity at national level important, additional will also required. Using case examples, we highlight that requirements differ from those GM crop plants previously authorized commercial use in Union.

Язык: Английский

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Epigenome editing: A new approach to aquaculture breeding

Reviews in Aquaculture, Год журнала: 2024, Номер 16(4), С. 1463 - 1466

Опубликована: Июнь 5, 2024

Язык: Английский

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