Pandemic-Proofing: Intercepting Zoonotic Spillover Events DOI Creative Commons
Bharti Bhatia, Sudipta Sonar, Seema A. Khan

и другие.

Pathogens, Год журнала: 2024, Номер 13(12), С. 1067 - 1067

Опубликована: Дек. 3, 2024

Zoonotic spillover events pose a significant and growing threat to global health. By focusing on preventing these cross-species transmissions, we can significantly mitigate pandemic risks. This review aims analyze the mechanisms of zoonotic events, identify key risk factors, propose evidence-based prevention strategies reduce future threats. Through comprehensive literature analysis major databases including PubMed, Web Science, Scopus from 1960–2024, examined documented their outcomes, intervention strategies. article emphasizes that targeting root cause—the event itself—is averting pandemics. analyzing historical contemporary outbreaks, extract crucial insights into dynamics transmission. Factors underlying include increased human–animal contact due habitat encroachment, agricultural intensification, wildlife trade. Climate change, travel, inadequate healthcare infrastructure exacerbate The diversity potential viral reservoirs rapid evolution present challenges for prediction prevention. Solutions enhancing surveillance populations, improving biosecurity measures, investing in diagnostic capabilities, promoting sustainable management. A “One Health” approach integrating human, animal, environmental health is crucial. Predictive modelling, international cooperation, public education are Developing pre-exposure prophylactics post-exposure treatments essential mitigating outbreaks. While obstacles remain, advances genomics ecological modelling offer hope. proactive, addressing causes vital safeguarding against

Язык: Английский

Land use-induced spillover: a call to action to safeguard environmental, animal, and human health DOI Creative Commons
Raina K. Plowright, Jamie K. Reaser, Harvey Locke

и другие.

The Lancet Planetary Health, Год журнала: 2021, Номер 5(4), С. e237 - e245

Опубликована: Март 7, 2021

The rapid global spread and human health impacts of SARS-CoV-2, the virus that causes COVID-19, show humanity's vulnerability to zoonotic disease pandemics. Although anthropogenic land use change is known be major driver pathogen spillover from wildlife populations, scientific underpinnings use-induced have rarely been investigated landscape perspective. We call for interdisciplinary collaborations advance knowledge on implications emergence with a view toward informing decisions needed protect health. In particular, we urge mechanistic focus infect–shed–spill–spread cascade enable protection immunity—the ecological conditions reduce risk reservoir hosts—as conservation biosecurity priority. Results are urgently formulate an integrated, holistic set science-based policy management measures effectively cost-efficiently minimise risk. consider opportunities better institute necessary collaboration, address primary technical challenges, issues warrant particular attention security local scales.

Язык: Английский

Процитировано

308

Pathogen spillover driven by rapid changes in bat ecology DOI Creative Commons
Peggy Eby, Alison J. Peel, Andrew Hoegh

и другие.

Nature, Год журнала: 2022, Номер 613(7943), С. 340 - 344

Опубликована: Ноя. 16, 2022

During recent decades, pathogens that originated in bats have become an increasing public health concern. A major challenge is to identify how those spill over into human populations generate a pandemic threat

Язык: Английский

Процитировано

162

A meta-analysis on global change drivers and the risk of infectious disease DOI
Michael B. Mahon, Alexandra Sack, O. Alejandro Aleuy

и другие.

Nature, Год журнала: 2024, Номер 629(8013), С. 830 - 836

Опубликована: Май 8, 2024

Язык: Английский

Процитировано

50

Biodiversity and human health: A scoping review and examples of underrepresented linkages DOI Creative Commons
Jake M. Robinson, Andrew C. Breed,

Araceli Camargo

и другие.

Environmental Research, Год журнала: 2024, Номер 246, С. 118115 - 118115

Опубликована: Янв. 9, 2024

Mounting evidence supports the connections between exposure to environmental typologies––such as green spaces––and human health. However, mechanistic links that connect biodiversity (the variety of life) and health, extent supporting remain less clear. Here, we undertook a scoping review map health summarise levels associated using an established weight framework. Distinct from other reviews, provide additional context regarding environment-microbiome-health axis, evaluate buffering pathway (e.g., impacts on air pollution), examples three under- or minimally-represented linkages. The are (1) Indigenous Peoples' (2) urban social equity, (3) COVID-19. We observed moderate level support microbiota-human moderate-high broader nature pathways greenspace) various outcomes, stress reduction enhanced wellbeing improved cohesion. studies did not typically include specific metrics, indicating clear research gaps. Further is required understand causative metrics such taxonomy, diversity/richness, structure, function) outcomes. There well-established frameworks assess effects broad classifications These can assist future in linking Our underrepresented linkages highlight roles its loss lived experiences, infectious diseases, sovereignty livelihoods. More awareness these socioecological interconnections needed.

Язык: Английский

Процитировано

25

Pathogens and planetary change DOI Creative Commons
Colin J. Carlson, Cole B. Brookson, Daniel J. Becker

и другие.

Опубликована: Янв. 15, 2025

Emerging infectious diseases, biodiversity loss, and anthropogenic environmental change are interconnected crises with massive social ecological costs. In this Review, we discuss how pathogens parasites responding to global change, the implications for pandemic prevention conservation. Ecological evolutionary principles help explain why both pandemics wildlife die-offs becoming more common; land-use loss often followed by an increase in zoonotic vector-borne diseases; some species, such as bats, host so many emerging pathogens. To prevent next pandemic, scientists should focus on monitoring limiting spread of a handful high-risk viruses, especially at key interfaces farms live-animal markets. But address much broader set disease risks associated Anthropocene, decision-makers will need develop comprehensive strategies that include pathogen surveillance across species ecosystems; conservation-based interventions reduce human–animal contact protect health; health system strengthening; improvements epidemic preparedness response. Scientists can contribute these efforts filling gaps data, expanding evidence base disease–driver relationships interventions. This Review explores relationship between diseases connected changes Anthropocene.

Язык: Английский

Процитировано

9

Human-mediated impacts on biodiversity and the consequences for zoonotic disease spillover DOI Creative Commons
Caroline K. Glidden, Nicole Nova, Morgan P. Kain

и другие.

Current Biology, Год журнала: 2021, Номер 31(19), С. R1342 - R1361

Опубликована: Окт. 1, 2021

Язык: Английский

Процитировано

73

Disease control tools to secure animal and public health in a densely populated world DOI Creative Commons
Johannes Charlier, Herman W. Barkema, Paul Becher

и другие.

The Lancet Planetary Health, Год журнала: 2022, Номер 6(10), С. e812 - e824

Опубликована: Окт. 1, 2022

Animal health is a prerequisite for global health, economic development, food security, quality, and poverty reduction, while mitigating against climate change biodiversity loss. We did qualitative review of 53 infectious diseases in terrestrial animals with data from DISCONTOOLS, specialist database prioritisation model focusing on research gaps improving disease control animals. Many do not have any appropriate tools, but the suggests that we should focus international efforts Nipah virus infection, African swine fever, contagious bovine pleuropneumonia, peste des petits ruminants, sheeppox goatpox, avian influenza, Rift Valley foot mouth disease, tuberculosis, greatest impact UN's Sustainable Development Goals. Easy to use accurate diagnostics are available many animal diseases. However, there an urgent need development stable durable can differentiate infected vaccinated animals, exploit rapid technological advances, make widely affordable. Veterinary vaccines important dealing endemic, new, emerging fundamental needed improve convenience duration immunity, establish performant marker vaccines. The largest gap pharmaceuticals threat pathogens developing resistance drugs, particular bacterial parasitic (protozoal, helminth, arthropod) pathogens. propose discuss five priorities will help deliver sustainable healthy planet: vaccinology, antimicrobial resistance, mitigation adaptation, digital epidemic preparedness.

Язык: Английский

Процитировано

41

Plant biosecurity and One Health: government and industry roles as risk creators and mitigators DOI Creative Commons
John I. Alawneh, Mohammad Mahmudul Hassan, James Camac

и другие.

One Health Outlook, Год журнала: 2025, Номер 7(1)

Опубликована: Апрель 25, 2025

Язык: Английский

Процитировано

1

Impacts of the COVID-19 Pandemic and the Russia–Ukraine Conflict on Land Use across the World DOI Creative Commons
Vítor João Pereira Domingues Martinho

Land, Год журнала: 2022, Номер 11(10), С. 1614 - 1614

Опубликована: Сен. 21, 2022

The impacts of the COVID-19 pandemic and Russia–Ukraine crisis on world economy are real. However, these implications do not appear to be symmetric across countries different economic sectors. Indeed, consequences two shocks more severe for some countries, regions activities than others. Considering importance agricultural sector global food security, it is important understand conflict dimensions agriculture, namely land use. Given scarcity data last few years available from various statistical databases, this research mainly considers insights highlighted in literature implications, dimensions, most recent shocks. study here presented shows that has had impact use changes pandemic, promoting adjustments decisions farmers policymakers deal with constraints agri-food chains. Nonetheless, were totally explored.

Язык: Английский

Процитировано

27

Can restoration of fire‐dependent ecosystems reduce ticks and tick‐borne disease prevalence in the eastern United States? DOI
Michael R. Gallagher, Jesse K. Kreye, Erika T. Machtinger

и другие.

Ecological Applications, Год журнала: 2022, Номер 32(7)

Опубликована: Апрель 15, 2022

Over the past century, fire suppression has facilitated broad ecological changes in composition, structure, and function of fire-dependent landscapes throughout eastern US, which are decline. These have likely contributed mechanistically to enhancement habitat conditions that favor pathogen-carrying tick species, key wildlife hosts ticks, interactions fostered pathogen transmission among them humans. While long-running paradigm for limiting human exposure tick-borne diseases focuses responsibility on individual prevention, continued expansion medically important populations, increased incidence disease humans, emergence novel highlights need additional approaches stem this public health challenge. Another approach potential be a cost-effective widely applied but remains largely overlooked is use prescribed ecologically restore degraded ticks transmission. We examine role its effects within United States, especially examining life cycles forest-dwelling shifts regional-scale over concept frequent may helped moderate populations prior so-called fire-suppression era characterized century. explore mechanisms how restoration can reduce incorporating into broader strategy managing challenges, limitations, research needs burning reduction.

Язык: Английский

Процитировано

24