Frontiers in Nutrition,
Год журнала:
2022,
Номер
9
Опубликована: Окт. 21, 2022
Vitamin
B
and
its
derivatives
possess
diverse
physiological
functions
are
essential
micronutrients
for
humans.
Their
variation
in
crops
is
important
the
identification
of
genetic
resources
used
to
develop
new
varieties
with
enhanced
vitamin
B.
In
this
research,
remarkable
variations
were
observed
kernels
156
maize
inbred
lines,
ranging
from
107.61
2654.54
μg
per
100
g
B1,
1.19–37.37
B2,
19.60–213.75
B3,
43.47–590.86
B5,
138.59–1065.11
B6.
Growing
inbreeds
Hainan
Hebei
provinces
China
revealed
environmental
genotype
interactions
among
these
vitamins
correlations
between
them
grain.
Several
lines
identified
as
good
sources
promising
germplasms
breeding,
namely
By855
Si273
overall
rich
all
studied
vitamins,
GY386B
CML118
specially
enriched
The
present
study
can
assist
breeders
germplasm
biofortification
offer
people
nutritious
foods.
Journal of Integrative Plant Biology,
Год журнала:
2025,
Номер
unknown
Опубликована: Май 16, 2025
ABSTRACT
Hidden
hunger,
caused
by
chronic
micronutrient
deficiencies,
affects
billions
of
people
worldwide
and
remains
a
critical
public
health
issue
despite
progress
in
food
production.
Biofortification
offers
promising
solution
enhancing
nutrient
levels
within
plant
tissues
through
traditional
breeding
or
advanced
biotechnologies.
Recent
advancements
synthetic
biology
have
significantly
improved
biofortification
strategies,
enabling
precise
targeted
enrichment.
This
mini‐review
outlines
five
core
strategies
biology‐based
biofortification:
overexpression
endogenous
biosynthetic
genes,
introduction
heterologous
pathways,
expression
nutrient‐specific
transporters,
optimization
transcriptional
regulation,
protein
(directed)
evolution.
Vitamin
B
1
serves
as
primary
illustrative
example
due
to
its
historical
importance
ongoing
relevance.
breakthroughs,
particularly
from
Chinese
research
teams,
are
also
highlighted.
Together,
these
offer
transformative
potential
for
addressing
global
nutritional
challenges
precise,
sustainable
innovative
plant‐based
approaches.
Current Opinion in Biotechnology,
Год журнала:
2024,
Номер
87, С. 103132 - 103132
Опубликована: Апрель 26, 2024
In
the
post-Green
Revolution
era,
disparities
in
dietary
access,
rising
obesity
rates,
demographic
shifts,
adoption
of
plant-based
diets,
and
impact
climate
change
collectively
contribute
to
a
progressive
decline
nutritional
value,
exacerbating
B
vitamin
deficiencies
across
both
low-
high-income
countries.
While
prevailing
focus
biofortification
has
been
on
three
micronutrients
-
provitamin
A,
iron,
zinc
utilizing
conventional
breeding,
it
is
imperative
diversify
strategies
combat
micronutrient
malnutrition.
Metabolic
engineering,
facilitated
by
biotechnological
tools,
presents
promising
avenue,
contingent
upon
advances
fundamental
knowledge,
technological
innovation,
regulatory
updates,
sustained
public
funding.
Recognizing
intricate
metabolic
interplay
vitamins
plants
humans,
comprehensive
'from
metabolism
metabolism'
approach
crucial
for
designing
effective
that
target
multiple
vitamins.
This
holistic
perspective
also
extends
beyond
individual
crops
encompass
entire
food
chain,
complex
socioeconomic
ecosystem
necessitates
paradigm
shift,
prioritizing
quality
over
quantity.
Vitamin
Bs,
a
group
of
water-soluble
compounds,
are
essential
nutrients
for
almost
all
living
organisms.
However,
due
to
their
structural
heterogeneity,
rapid
and
simultaneous
analysis
multiple
vitamin
Bs
is
still
challenging.
In
this
paper,
it
discovered
that
hetero-octameric
Drought
stress
imposes
a
serious
challenge
to
cultivate
wheat,
restricting
its
growth.
reduces
the
capability
of
plant
uptake
essential
nutrients.
This
causes
stunted
growth,
development
and
yield.
Traditional
ways
increase
wheat
growth
under
drought
have
shortcomings.
Using
plant-growth-promoting
rhizobacteria
(PGPR)
has
proved
feasible
eco-friendly
way
enhance
even
stress.
Combining
PGPR
in
consortiums
further
boosts
up
their
effects.
In
this
study,
we
checked
efficacy
drought-tolerant
Bacillus
halotolerans,
Pseudomonas
sihuiensis
atrophaeus
combination.
These
strains
were
allowed
grow
on
PEG
6000
with
concentrations
(-0.15,
-0.49,
-0.73
-
1.2)
Mega
Pascal
(MPa)
alone
Furthermore,
Fourier
transmission
infrared
(FTIR)
spectroscopy
scanning
electron
microscopy
(SEM)
used.
Their
biochemical
traits
such
as
solubilization
K,
P
Zn
synthesis
siderophore,
indole
acetic
acid
(IAA),
protease,
amylase,
hydrogen
cyanide
(HCN)
1-aminocyclopropane-1-carboxylate
(ACC)
deaminase
done.
addition
this,
investigated
optimum
folic
concentration
i.e
150
ppm
for
against
We
conducted
pot
experiment
check
growth-enhancing
drought-mitigating
effects
consortium
As
result,
found
significantly
increased
biomass,
relative
water
content
(RWC),
chlorophyll
content,
antioxidants
including
glutathione
reductase
total
soluble
sugars
protein
all
treatments.
However,
combined
treatment
bacterial
showed
maximum
potential
boost
survival
drought.
also
minerals
by
after
treatments
nutrient
co-effect
believe
is
first
study
that
optimal
dose
wheat.
Our
research
novel
seek
investigate
along
comprising
grown
Journal of Advanced Research,
Год журнала:
2024,
Номер
unknown
Опубликована: Окт. 1, 2024
Potato
(Solanum
tuberosum
L.)
is
the
fourth
most
important
food
crop
after
rice,
wheat
and
maize
in
world
with
potential
to
feed
world's
population,
potato
a
major
staple
many
countries.
Currently,
grown
more
than
100
countries
consumed
by
1
billion
people
worldwide,
global
annual
output
exceeds
300
million
tons.
With
rapid
increase
will
play
key
role
supply.
These
aspects
have
driven
scientists
genetically
engineer
for
yield
nutrition
improvement.
International Journal of Molecular Sciences,
Год журнала:
2023,
Номер
24(14), С. 11296 - 11296
Опубликована: Июль 10, 2023
Thiamine
(vitamin
B1)
is
essential
for
the
brain.
This
attributed
to
coenzyme
role
of
thiamine
diphosphate
(ThDP)
in
glucose
and
energy
metabolism.
The
synthetic
prodrug,
thioester
benfotiamine
(BFT),
has
been
extensively
studied
beneficial
effects
both
rodent
models
neurodegeneration
human
clinical
studies.
BFT
no
known
adverse
improves
cognitive
outcomes
patients
with
mild
Alzheimer's
disease.
In
cell
culture
animal
models,
antioxidant
anti-inflammatory
properties
that
seem
be
mediated
by
a
mechanism
independent
function
ThDP.
Recent
vitro
studies
show
another
thioester,
O,S-dibenzoylthiamine
(DBT),
even
more
efficient
than
BFT,
especially
respect
its
potency,
effective
at
lower
concentrations.
thioesters
have
pleiotropic
linked
an
increase
circulating
concentrations
possibly
hitherto
unidentified
open
thiazole
ring
derivatives.
identification
active
neuroprotective
metabolites
clarification
their
action
extremely
promising
perspectives
field
neurodegenerative,
neurodevelopmental,
psychiatric
conditions.
present
review
aims
summarize
existing
data
on
give
comprehensive
account.
