Longitudinal assessments of functional near-infrared spectroscopy background functional connectivity in low- and middle-income infants during a social cognition task.

Journal of Experimental Psychology General, Год журнала: 2024, Номер 153(3), С. 798 - 813

Опубликована: Янв. 25, 2024

social cognition task.

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Machines, mathematics, and modules: the potential to provide real-time metrics for pain under anesthesia

Neurophotonics, Год журнала: 2024, Номер 11(01)

Опубликована: Фев. 22, 2024

The brain-based assessments under anesthesia have provided the ability to evaluate pain/nociception during surgery and potential prevent long-term evolution of chronic pain. Prior studies shown that functional near-infrared spectroscopy (fNIRS)-measured changes in cortical regions such as primary somatosensory polar frontal cortices show consistent response evoked ongoing pain awake, sedated, anesthetized patients. We take this basic approach integrate it into a framework could provide real-time measures peri-surgical period. This application significant implications for providing analgesia surgery, practice currently lacks quantitative evidence guide patient tailored management. Through simple readout “pain” or “no pain,” proposed system diminish eliminate levels intraoperative, early post-operative, potentially, transition post-surgical system, when validated, also be applied analgesic efficacy clinic.

Язык: Английский

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Directed physiological networks in the human prefrontal cortex at rest and post transcranial photobiomodulation

Scientific Reports, Год журнала: 2024, Номер 14(1)

Опубликована: Май 3, 2024

Cerebral infra-slow oscillation (ISO) is a source of vasomotion in endogenic (E; 0.005-0.02 Hz), neurogenic (N; 0.02-0.04 and myogenic (M; 0.04-0.2 Hz) frequency bands. In this study, we quantified changes prefrontal concentrations oxygenated hemoglobin (Δ[HbO]) redox-state cytochrome c oxidase (Δ[CCO]) as hemodynamic metabolic activity metrics, electroencephalogram (EEG) powers electrophysiological activity, using concurrent measurements 2-channel broadband near-infrared spectroscopy EEG on the forehead 22 healthy participants at rest. After preprocessing, multi-modality signals were analyzed generalized partial directed coherence to construct unilateral neurophysiological networks among three metrics (with simplified symbols HbO, CCO, EEG) each E/N/M band. The links these represent neurovascular, neurometabolic, metabolicvascular coupling (NVC, NMC, MVC). results illustrate that demand for oxygen by neuronal metabolism (EEG CCO) drives supply (HbO) all bands resting cortex. Furthermore, investigate effect transcranial photobiomodulation (tPBM), performed sham-controlled study delivering an 800-nm laser beam left right cortex same participants. performing data processing statistical analysis, obtained novel important findings: tPBM delivered either side triggered alteration or reversal network couplings entities (i.e., frequency-specific powers) physiological E N bands, demonstrating during post-tPBM period, both drive (PFC). Overall, revealed facilitates significant modulation directionality electrophysiological, metabolic, activities.

Язык: Английский

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The neural characteristics influencing literacy outcome in children with cochlear implants

Brain Communications, Год журнала: 2025, Номер 7(2)

Опубликована: Янв. 1, 2025

Early hearing intervention in children with congenital loss is critical for improving auditory development, speech recognition and both expressive receptive language, which translates into better educational outcomes quality of life. In receiving aids or cochlear implants, adaptive potentially maladaptive neural reorganization can mitigate higher-level functions that impact reading. The focus the present study was to dissect underpinnings reading networks implants assess how these mediate ability implants. Cortical activity obtained using naturalistic stimuli from 75 (50 implant recipients, aged 7-17, 25 age-matched typical hearing) functional near-infrared spectroscopy. Assessment basic skill completed Reading Inventory Scholastic Evaluation. We computed directed connectivity haemodynamic reading-associated anterior posterior brain regions time-frequency causality estimation method known as temporal partial coherence. influence implant-related clinical measures on outcome extent mediated effects were examined structural equation modelling. Our findings reveal timing (e.g. age first aid) significantly influenced their ability. Furthermore, reading-related processes (word decoding, vocabulary, morphology sentence processing) substantially by within circuits. Notably, differed across various skills. Hearing age, defined at a participant received adequate access sound, initial implantation emerged robust predictors proficiency. current one identify characteristics emphasize importance duration deafness early enhancing strengthening network connections. However, evidence further suggested such positive influences cannot fully offset detrimental deprivation. Consequently, additional, perhaps more specialized, interventions might be necessary maximize benefits prosthetic intervention.

Язык: Английский

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Enhancement of Frequency-Specific Hemodynamic Power and Functional Connectivity by Transcranial Photobiomodulation in Healthy Humans

Frontiers in Neuroscience, Год журнала: 2022, Номер 16

Опубликована: Июнь 10, 2022

Transcranial photobiomodulation (tPBM) has been considered a safe and effective brain stimulation modality being able to enhance cerebral oxygenation neurocognitive function. To better understand the underlying neurophysiological effects of tPBM in human brain, we utilized 111-channel functional near infrared spectroscopy (fNIRS) system map hemodynamic responses over whole head 8-min with 1,064-nm laser given on forehead 19 healthy participants. Instead analyzing broad-frequency signals (0-0.2 Hz), investigated frequency-specific three infra-slow oscillation (ISO) components consisting endogenic, neurogenic, myogenic vasomotions. Significant changes induced by spectral power oxygenated hemoglobin concentration (Δ[HbO]), connectivity (FC), global network metrics at each ISO frequency bands were identified mapped topographically for comparisons. Our novel findings revealed that significantly increased endogenic Δ[HbO] powers right frontopolar area site. Also, demonstrated enabled significant enhancements FC across cortical regions as well several metrics. These consistent recent reports met expectation is highly associated endothelial activity, which stimulated tPBM-evoked nitric oxide (NO) release.

Язык: Английский

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Physiological Noise Filtering in Functional Near-Infrared Spectroscopy Signals Using Wavelet Transform and Long-Short Term Memory Networks

Bioengineering, Год журнала: 2023, Номер 10(6), С. 685 - 685

Опубликована: Июнь 4, 2023

Activated channels of functional near-infrared spectroscopy are typically identified using the desired hemodynamic response function (dHRF) generated by a trial period. However, this approach is not possible for an unknown In paper, innovative method dHRF proposed, which extracts fluctuating signals during resting state maximal overlap discrete wavelet transform, identifies low-frequency wavelets corresponding to physiological noise, trains them long-short term memory networks, and predicts/subtracts task session. The motivation prediction maintain phase information noise at start time task, because signal extended from This technique decomposes data into nine uses fifth ninth learning prediction. eighth wavelet, error difference between with without 15-s window appeared be largest. Considering difficulty in removing when activation period near proposed can alternative solution conventional applicable. passive brain-computer interfaces, estimating brain starting necessary.

Язык: Английский

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Site-specific effects of 800- and 850-nm forehead transcranial photobiomodulation on prefrontal bilateral connectivity and unilateral coupling in young adults

Neurophotonics, Год журнала: 2023, Номер 10(02)

Опубликована: Июнь 5, 2023

Transcranial photobiomodulation (tPBM) is a noninvasive neuromodulation method that facilitates the improvement of human cognition. However, limited information available in literature on wavelength- and site-specific effects prefrontal tPBM. Moreover, 2-channel broadband near-infrared spectroscopy (2-bbNIRS) new approach for quantifying infra-slow oscillations (ISO; 0.005 to 0.2 Hz) neurophysiological networks resting brain vivo.We aim prove hypothesis hemodynamic metabolic activities cortex are significantly modulated by tPBM modulation different ISO bands.Noninvasive 8-min with an 800- or 850-nm laser sham was delivered either side forehead 26 healthy young adults. A 2-bbNIRS unit used record activity 7 min before after tPBM/sham. The measured time series were analyzed frequency domain determine coherence at each three bands. Sham-controlled values represent tPBM-induced networks.Prefrontal wavelength lateral (1) increased ipsilateral metabolic-hemodynamic coupling endogenic band (2) desynchronized bilateral metabolism neurogenic vascular smooth-muscle hemodynamics myogenic band. Site-specific also observed significant enhancement connectivity right 800-nm tPBM.Prefrontal can modulate bilaterally unilaterally cortex. Such site- wavelength-specific

Язык: Английский

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Multimodal pre-screening can predict BCI performance variability: A novel subject-specific experimental scheme

Computers in Biology and Medicine, Год журнала: 2023, Номер 168, С. 107658 - 107658

Опубликована: Ноя. 2, 2023

Язык: Английский

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Most favorable stimulation duration in the sensorimotor cortex for fNIRS-based BCI

Biomedical Optics Express, Год журнала: 2021, Номер 12(10), С. 5939 - 5939

Опубликована: Авг. 25, 2021

One of the primary objectives brain-computer interface (BCI) is to obtain a command with higher classification accuracy within shortest possible time duration. Therefore, this study evaluates several stimulation durations propose duration that can yield highest accuracy. Furthermore, aims address inherent delay in hemodynamic responses (HRs) for generation time. To end, HRs sensorimotor cortex were evaluated functional near-infrared spectroscopy (fNIRS)-based BCI. evoke brain activity, right-hand-index finger poking and tapping tasks used. In study, six different (i.e., 1, 3, 5, 7, 10, 15 s) tested on 10 healthy male subjects. Upon stimulation, temporal features multiple windows utilized extract features. The extracted then classified using linear discriminant analysis. results main HR showed 5 s could accuracy, i.e., 74%, combination mean maximum value However, not significantly from obtained stimulation. further validate results, initial dip was performed. endorsed finding an average 73.5% minimum peak skewness window. based all other (

Язык: Английский

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Prefrontal cortical connectivity and coupling of infraslow oscillation in the resting human brain: a 2-channel broadband NIRS study

Cerebral Cortex Communications, Год журнала: 2022, Номер 3(3)

Опубликована: Июль 1, 2022

Abstract The resting-state infraslow oscillation (ISO) of the cerebral cortex reflects neurophysiological state human brain. ISO results from distinct vasomotion with endogenic (E), neurogenic (N), and myogenic (M) frequency bands. Quantification prefrontal in cortical hemodynamics metabolism resting brain may facilitate identification objective features that are characteristic certain disorders. goal this study was to explore quantify concentration changes oxygenated hemoglobin (Δ[HbO]) redox-state cytochrome c oxidase (Δ[CCO]) as hemodynamic metabolic activity metrics all 3 E/N/M Two-channel broadband near-infrared spectroscopy (2-bbNIRS) enabled measurements forehead 26 healthy young participants a once week for 5 weeks. After quantifying spectral amplitude (SA) coherence at each band, several key statistically reliable were obtained features: (i) SA Δ[HbO] bands, (ii) Δ[CCO] M (iii) bilateral connectivity across E N (iv) unilateral hemodynamic–metabolic coupling These have promising potential be developed biomarkers clinical applications future.

Язык: Английский

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