Despite
various
approaches
to
immunoassay
and
chromatography
for
monitoring
cortisol
concentrations,
conventional
methods
require
bulky
external
equipment,
which
limits
their
use
as
mobile
health
care
systems.
Here,
we
describe
a
human
pilot
trial
of
soft,
smart
contact
lens
real-time
detection
the
concentration
in
tears
using
smartphone.
A
sensor
formed
graphene
field-effect
transistor
can
measure
with
limit
10
pg/ml,
is
low
enough
detect
tears.
In
addition,
this
soft
only
requires
integration
transparent
antennas
wireless
communication
circuits
make
smartphone
device
needed
operate
remotely
without
obstructing
wearer's
view.
Furthermore,
vivo
tests
live
rabbits
experiment
confirmed
good
biocompatibility
reliability
noninvasive,
solution.
Chemical Reviews,
Год журнала:
2019,
Номер
119(8), С. 5461 - 5533
Опубликована: Янв. 28, 2019
Bio-integrated
wearable
systems
can
measure
a
broad
range
of
biophysical,
biochemical,
and
environmental
signals
to
provide
critical
insights
into
overall
health
status
quantify
human
performance.
Recent
advances
in
material
science,
chemical
analysis
techniques,
device
designs,
assembly
methods
form
the
foundations
for
uniquely
differentiated
type
technology,
characterized
by
noninvasive,
intimate
integration
with
soft,
curved,
time-dynamic
surfaces
body.
This
review
summarizes
latest
this
emerging
field
"bio-integrated"
technologies
comprehensive
manner
that
connects
fundamental
developments
chemistry,
engineering
sensing
have
potential
widespread
deployment
societal
benefit
care.
An
introduction
chemistries
materials
active
components
these
contextualizes
essential
design
considerations
sensors
associated
platforms
appear
following
sections.
The
subsequent
content
highlights
most
advanced
biosensors,
classified
according
their
ability
capture
information.
Additional
sections
feature
schemes
electrically
powering
strategies
achieving
fully
integrated,
wireless
systems.
concludes
an
overview
key
remaining
challenges
summary
opportunities
where
chemistry
will
be
critically
important
continued
progress.
Sensors,
Год журнала:
2019,
Номер
19(4), С. 800 - 800
Опубликована: Фев. 15, 2019
Current
glucose
monitoring
methods
for
the
ever-increasing
number
of
diabetic
people
around
world
are
invasive,
painful,
time-consuming,
and
a
constant
burden
household
budget.
The
non-invasive
technology
overcomes
these
limitations,
which
this
topic
is
significantly
being
researched
represents
an
exciting
highly
sought
after
market
many
companies.
This
review
aims
to
offer
up-to-date
report
on
leading
technologies
(NI)
minimally-invasive
(MI)
sensors,
devices
currently
available
in
market,
regulatory
framework
accuracy
assessment,
new
approaches
under
study
by
representative
groups
developers,
algorithm
types
signal
enhancement
value
prediction.
also
discusses
future
trend
detection
analyzing
usage
different
bands
electromagnetic
spectrum.
concludes
that
adoption
use
unavoidable
closer
become
reality.
Advanced Materials,
Год журнала:
2019,
Номер
32(15)
Опубликована: Июнь 27, 2019
Abstract
Recent
advances
in
material
innovation
and
structural
design
provide
routes
to
flexible
hybrid
electronics
that
can
combine
the
high‐performance
electrical
properties
of
conventional
wafer‐based
with
ability
be
stretched,
bent,
twisted
arbitrary
shapes,
revolutionizing
transformation
traditional
healthcare
digital
healthcare.
Here,
for
preparation
are
reviewed,
a
brief
chronology
these
is
given,
biomedical
applications
bioelectrical
monitoring
stimulation,
optical
treatment,
acoustic
imitation
monitoring,
bionic
touch,
body‐fluid
testing
described.
In
conclusion,
some
remarks
on
challenges
future
research
presented.
Personalized Medicine,
Год журнала:
2018,
Номер
15(5), С. 429 - 448
Опубликована: Сен. 1, 2018
Wearable
sensors
are
already
impacting
healthcare
and
medicine
by
enabling
health
monitoring
outside
of
the
clinic
prediction
events.
This
paper
reviews
current
prospective
wearable
technologies
their
progress
toward
clinical
application.
We
describe
underlying
common,
commercially
available
early-stage
devices
outline
research,
when
available,
to
support
use
these
in
healthcare.
cover
applications
following
areas:
metabolic,
cardiovascular
gastrointestinal
monitoring;
sleep,
neurology,
movement
disorders
mental
health;
maternal,
pre-
neo-natal
care;
pulmonary
environmental
exposures.
Finally,
we
discuss
challenges
associated
with
adoption
ecosystem
areas
for
future
research
development.
Advanced Materials,
Год журнала:
2018,
Номер
30(33)
Опубликована: Июнь 11, 2018
Wearables
as
medical
technologies
are
becoming
an
integral
part
of
personal
analytics,
measuring
physical
status,
recording
physiological
parameters,
or
informing
schedule
for
medication.
These
continuously
evolving
technology
platforms
do
not
only
promise
to
help
people
pursue
a
healthier
life
style,
but
also
provide
continuous
data
actively
tracking
metabolic
diagnosis,
and
treatment.
Advances
in
the
miniaturization
flexible
electronics,
electrochemical
biosensors,
microfluidics,
artificial
intelligence
algorithms
have
led
wearable
devices
that
can
generate
real-time
within
Internet
things.
be
configured
make
conformal
contact
with
epidermal,
ocular,
intracochlear,
dental
interfaces
collect
biochemical
electrophysiological
signals.
This
article
discusses
consumer
trends
commercial
emerging
devices,
fabrication
methods.
It
reviews
monitoring
vital
signs
using
stimuli-responsive
materials
drug
delivery,
closed-loop
theranostic
systems.
covers
future
challenges
augmented,
virtual,
mixed
reality,
communication
modes,
energy
management,
displays,
conformity,
safety.
The
development
patient-oriented
their
incorporation
randomized
clinical
trials
will
facilitate
design
safe
effective
approaches.
Chemical Reviews,
Год журнала:
2022,
Номер
122(18), С. 14679 - 14721
Опубликована: Авг. 18, 2022
With
the
rapid
development
of
optoelectronic
fields,
electrochromic
(EC)
materials
and
devices
have
received
remarkable
attention
shown
attractive
potential
for
use
in
emerging
wearable
portable
electronics,
electronic
papers/billboards,
see-through
displays,
other
new-generation
due
to
advantages
low
power
consumption,
easy
viewing,
flexibility,
stretchability,
etc.
Despite
continuous
progress
related
determining
how
make
electrochromics
truly
meet
requirements
mature
displays
(e.g.,
ideal
overall
performance)
has
been
a
long-term
problem.
Therefore,
commercialization
relevant
high-quality
products
is
still
its
infancy.
In
this
review,
we
will
focus
on
EC
including
two
mainstream
display
prototypes
(segmented
pixel
displays)
their
commercial
applications.
Among
these
topics,
materials/devices,
performance,
construction
approaches,
processing
techniques
are
comprehensively
disscussed
reviewed.
We
also
outline
current
barriers
with
possible
solutions
discuss
future
field.
Nanomaterials,
Год журнала:
2019,
Номер
9(6), С. 813 - 813
Опубликована: Май 29, 2019
Wearable
devices
are
becoming
widespread
in
a
wide
range
of
applications,
from
healthcare
to
biomedical
monitoring
systems,
which
enable
continuous
measurement
critical
biomarkers
for
medical
diagnostics,
physiological
health
and
evaluation.
Especially
as
the
elderly
population
grows
globally,
various
chronic
acute
diseases
become
increasingly
important,
industry
is
changing
dramatically
due
need
point-of-care
(POC)
diagnosis
real-time
long-term
conditions.
have
evolved
gradually
form
accessories,
integrated
clothing,
body
attachments
inserts.
Over
past
few
decades,
tremendous
development
electronics,
biocompatible
materials
nanomaterials
has
resulted
implantable
that
prognosis
through
small
sensors
devices,
greatly
improve
quality
efficacy
services.
This
article
summarizes
wearable
been
developed
date,
provides
review
their
clinical
applications.
We
will
also
discuss
technical
barriers
challenges
future
prospects
on
biosensors
prevention,
personalized
medicine
monitoring.
Advanced Materials,
Год журнала:
2019,
Номер
32(15)
Опубликована: Июль 24, 2019
Abstract
Wearable
electronics
have
revolutionized
the
way
physiological
parameters
are
sensed,
detected,
and
monitored.
In
recent
years,
advances
in
flexible
stretchable
hybrid
created
emergent
properties
that
enhance
compliance
of
devices
to
our
skin.
With
their
unobtrusive
attributes,
skin
conformable
sensors
enable
applications
toward
real‐time
disease
diagnosis
continuous
healthcare
monitoring.
Herein,
critical
perspectives
future
digital
health
monitoring
provided,
emphasizing
its
role
sensing.
particular,
strategies
within
sensor
composition
render
flexibility
stretchability
while
maintaining
excellent
sensing
performance
considered.
Next,
novel
approaches
functionalization
for
physical
or
biochemical
stimuli
extensively
covered.
Subsequently,
wearable
measuring
such
as
strain,
pressure,
temperature,
well
biological
changes
metabolites
electrolytes
reported.
Finally,
implications
early
detection
discussed,
concluding
with
a
perspective
into
challenges
opportunities
emerging
designs
next
few
years.