Smart, soft contact lens for wireless immunosensing of cortisol DOI Creative Commons
Minjae Ku, Joohee Kim, Jong‐Eun Won

и другие.

Science Advances, Год журнала: 2020, Номер 6(28)

Опубликована: Июль 8, 2020

Despite various approaches to immunoassay and chromatography for monitoring cortisol concentrations, conventional methods require bulky external equipment, which limits their use as mobile health care systems. Here, we describe a human pilot trial of soft, smart contact lens real-time detection the concentration in tears using smartphone. A sensor formed graphene field-effect transistor can measure with limit 10 pg/ml, is low enough detect tears. In addition, this soft only requires integration transparent antennas wireless communication circuits make smartphone device needed operate remotely without obstructing wearer's view. Furthermore, vivo tests live rabbits experiment confirmed good biocompatibility reliability noninvasive, solution.

Язык: Английский

Wearable biosensors for healthcare monitoring DOI
Jayoung Kim, Alan S. Campbell, Berta Esteban‐Fernández de Ávila

и другие.

Nature Biotechnology, Год журнала: 2019, Номер 37(4), С. 389 - 406

Опубликована: Фев. 25, 2019

Язык: Английский

Процитировано

2609

Bio-Integrated Wearable Systems: A Comprehensive Review DOI
Tyler R. Ray, Jungil Choi, Amay J. Bandodkar

и другие.

Chemical Reviews, Год журнала: 2019, Номер 119(8), С. 5461 - 5533

Опубликована: Янв. 28, 2019

Bio-integrated wearable systems can measure a broad range of biophysical, biochemical, and environmental signals to provide critical insights into overall health status quantify human performance. Recent advances in material science, chemical analysis techniques, device designs, assembly methods form the foundations for uniquely differentiated type technology, characterized by noninvasive, intimate integration with soft, curved, time-dynamic surfaces body. This review summarizes latest this emerging field "bio-integrated" technologies comprehensive manner that connects fundamental developments chemistry, engineering sensing have potential widespread deployment societal benefit care. An introduction chemistries materials active components these contextualizes essential design considerations sensors associated platforms appear following sections. The subsequent content highlights most advanced biosensors, classified according their ability capture information. Additional sections feature schemes electrically powering strategies achieving fully integrated, wireless systems. concludes an overview key remaining challenges summary opportunities where chemistry will be critically important continued progress.

Язык: Английский

Процитировано

1038

The Progress of Glucose Monitoring—A Review of Invasive to Minimally and Non-Invasive Techniques, Devices and Sensors DOI Creative Commons
Wilbert Villena Gonzales, Ahmed Toaha Mobashsher, Amin Abbosh

и другие.

Sensors, Год журнала: 2019, Номер 19(4), С. 800 - 800

Опубликована: Фев. 15, 2019

Current glucose monitoring methods for the ever-increasing number of diabetic people around world are invasive, painful, time-consuming, and a constant burden household budget. The non-invasive technology overcomes these limitations, which this topic is significantly being researched represents an exciting highly sought after market many companies. This review aims to offer up-to-date report on leading technologies (NI) minimally-invasive (MI) sensors, devices currently available in market, regulatory framework accuracy assessment, new approaches under study by representative groups developers, algorithm types signal enhancement value prediction. also discusses future trend detection analyzing usage different bands electromagnetic spectrum. concludes that adoption use unavoidable closer become reality.

Язык: Английский

Процитировано

641

Multifunctional materials for implantable and wearable photonic healthcare devices DOI
Geon‐Hui Lee, Hanul Moon, Hyemin Kim

и другие.

Nature Reviews Materials, Год журнала: 2020, Номер 5(2), С. 149 - 165

Опубликована: Янв. 7, 2020

Язык: Английский

Процитировано

572

Flexible Hybrid Electronics for Digital Healthcare DOI
Yinji Ma, Yingchao Zhang,

Shisheng Cai

и другие.

Advanced Materials, Год журнала: 2019, Номер 32(15)

Опубликована: Июнь 27, 2019

Abstract Recent advances in material innovation and structural design provide routes to flexible hybrid electronics that can combine the high‐performance electrical properties of conventional wafer‐based with ability be stretched, bent, twisted arbitrary shapes, revolutionizing transformation traditional healthcare digital healthcare. Here, for preparation are reviewed, a brief chronology these is given, biomedical applications bioelectrical monitoring stimulation, optical treatment, acoustic imitation monitoring, bionic touch, body‐fluid testing described. In conclusion, some remarks on challenges future research presented.

Язык: Английский

Процитировано

529

Wearables and the Medical Revolution DOI Creative Commons
Jessilyn Dunn,

Ryan Runge,

M Snyder

и другие.

Personalized Medicine, Год журнала: 2018, Номер 15(5), С. 429 - 448

Опубликована: Сен. 1, 2018

Wearable sensors are already impacting healthcare and medicine by enabling health monitoring outside of the clinic prediction events. This paper reviews current prospective wearable technologies their progress toward clinical application. We describe underlying common, commercially available early-stage devices outline research, when available, to support use these in healthcare. cover applications following areas: metabolic, cardiovascular gastrointestinal monitoring; sleep, neurology, movement disorders mental health; maternal, pre- neo-natal care; pulmonary environmental exposures. Finally, we discuss challenges associated with adoption ecosystem areas for future research development.

Язык: Английский

Процитировано

518

Wearables in Medicine DOI Creative Commons
Ali K. Yetisen,

J. L. Martínez-Hurtado,

Barış Ünal

и другие.

Advanced Materials, Год журнала: 2018, Номер 30(33)

Опубликована: Июнь 11, 2018

Wearables as medical technologies are becoming an integral part of personal analytics, measuring physical status, recording physiological parameters, or informing schedule for medication. These continuously evolving technology platforms do not only promise to help people pursue a healthier life style, but also provide continuous data actively tracking metabolic diagnosis, and treatment. Advances in the miniaturization flexible electronics, electrochemical biosensors, microfluidics, artificial intelligence algorithms have led wearable devices that can generate real-time within Internet things. be configured make conformal contact with epidermal, ocular, intracochlear, dental interfaces collect biochemical electrophysiological signals. This article discusses consumer trends commercial emerging devices, fabrication methods. It reviews monitoring vital signs using stimuli-responsive materials drug delivery, closed-loop theranostic systems. covers future challenges augmented, virtual, mixed reality, communication modes, energy management, displays, conformity, safety. The development patient-oriented their incorporation randomized clinical trials will facilitate design safe effective approaches.

Язык: Английский

Процитировано

470

Emerging Electrochromic Materials and Devices for Future Displays DOI Creative Commons
Chang Gu,

Ai-Bo Jia,

Yu‐Mo Zhang

и другие.

Chemical Reviews, Год журнала: 2022, Номер 122(18), С. 14679 - 14721

Опубликована: Авг. 18, 2022

With the rapid development of optoelectronic fields, electrochromic (EC) materials and devices have received remarkable attention shown attractive potential for use in emerging wearable portable electronics, electronic papers/billboards, see-through displays, other new-generation due to advantages low power consumption, easy viewing, flexibility, stretchability, etc. Despite continuous progress related determining how make electrochromics truly meet requirements mature displays (e.g., ideal overall performance) has been a long-term problem. Therefore, commercialization relevant high-quality products is still its infancy. In this review, we will focus on EC including two mainstream display prototypes (segmented pixel displays) their commercial applications. Among these topics, materials/devices, performance, construction approaches, processing techniques are comprehensively disscussed reviewed. We also outline current barriers with possible solutions discuss future field.

Язык: Английский

Процитировано

458

Evolution of Wearable Devices with Real-Time Disease Monitoring for Personalized Healthcare DOI Creative Commons

Kyeonghye Guk,

Gaon Han,

Jaewoo Lim

и другие.

Nanomaterials, Год журнала: 2019, Номер 9(6), С. 813 - 813

Опубликована: Май 29, 2019

Wearable devices are becoming widespread in a wide range of applications, from healthcare to biomedical monitoring systems, which enable continuous measurement critical biomarkers for medical diagnostics, physiological health and evaluation. Especially as the elderly population grows globally, various chronic acute diseases become increasingly important, industry is changing dramatically due need point-of-care (POC) diagnosis real-time long-term conditions. have evolved gradually form accessories, integrated clothing, body attachments inserts. Over past few decades, tremendous development electronics, biocompatible materials nanomaterials has resulted implantable that prognosis through small sensors devices, greatly improve quality efficacy services. This article summarizes wearable been developed date, provides review their clinical applications. We will also discuss technical barriers challenges future prospects on biosensors prevention, personalized medicine monitoring.

Язык: Английский

Процитировано

455

Flexible Hybrid Sensors for Health Monitoring: Materials and Mechanisms to Render Wearability DOI
Yuji Gao, Longteng Yu, Joo Chuan Yeo

и другие.

Advanced Materials, Год журнала: 2019, Номер 32(15)

Опубликована: Июль 24, 2019

Abstract Wearable electronics have revolutionized the way physiological parameters are sensed, detected, and monitored. In recent years, advances in flexible stretchable hybrid created emergent properties that enhance compliance of devices to our skin. With their unobtrusive attributes, skin conformable sensors enable applications toward real‐time disease diagnosis continuous healthcare monitoring. Herein, critical perspectives future digital health monitoring provided, emphasizing its role sensing. particular, strategies within sensor composition render flexibility stretchability while maintaining excellent sensing performance considered. Next, novel approaches functionalization for physical or biochemical stimuli extensively covered. Subsequently, wearable measuring such as strain, pressure, temperature, well biological changes metabolites electrolytes reported. Finally, implications early detection discussed, concluding with a perspective into challenges opportunities emerging designs next few years.

Язык: Английский

Процитировано

421