Advanced Materials,
Год журнала:
2022,
Номер
35(10)
Опубликована: Дек. 28, 2022
Abstract
Real‐time
monitoring
of
human
health
can
be
significantly
improved
by
designing
novel
electronic
skin
(E‐skin)
platforms
that
mimic
the
characteristics
and
sensitivity
skin.
A
high‐quality
E‐skin
platform
simultaneously
monitor
multiple
physiological
metabolic
biomarkers
without
introducing
discomfort
or
irritation
is
an
unmet
medical
need.
Conventional
E‐skins
are
either
monofunctional
made
from
elastomeric
films
do
not
include
key
synergistic
features
natural
skin,
such
as
multi‐sensing,
breathability,
thermal
management
capabilities
in
a
single
patch.
Herein,
biocompatible
biodegradable
patch
based
on
flexible
gelatin
methacryloyl
aerogel
(FGA)
for
non‐invasive
continuous
interest
engineered
demonstrated.
Taking
advantage
cryogenic
temperature
treatment
slow
polymerization,
FGA
fabricated
with
highly
interconnected
porous
structure
displays
good
flexibility,
passive‐cooling
capabilities,
ultra‐lightweight
properties
make
it
comfortable
to
wear
long
periods
time.
It
also
provides
numerous
permeable
capillary
channels
thermal‐moisture
transfer,
ensuring
its
excellent
breathability.
Therefore,
FGA‐based
body
temperature,
hydration,
biopotentials
via
electrophysiological
sensors
detect
glucose,
lactate,
alcohol
levels
electrochemical
sensors.
This
work
offers
previously
unexplored
materials
strategy
next‐generation
superior
practicality.
Advanced Functional Materials,
Год журнала:
2023,
Номер
33(21)
Опубликована: Фев. 26, 2023
Abstract
Conductive
hydrogel‐based
epidermal
sensors
are
regarded
with
broad
prospects
in
bridging
the
gap
between
human
and
machine
for
personalized
healthcare.
However,
it
is
still
challenging
to
simultaneously
achieve
high
sensitivity,
wide
sensing
range,
reliable
cycling
stability
ultrasensitive
human–machine
interfacing,
along
brilliant
antiswelling
capability,
near‐infrared
(NIR)
light‐triggered
dissociation
drug
release
further
smart
on‐demand
photothermal
therapy.
Herein,
facile
preparation
of
a
flexible
multifunctional
sensor
from
elaborately
fabricated,
highly
stretchable,
MXene
hydrogel
presented.
It
exhibits
range
(up
350%
strain),
reproducibility
enabling
human‐machine
interfacing.
displays
excellent
capability
avoid
expanding
wound
due
excessive
swelling
Furthermore,
possesses
good
biocompatibility
robust
performance
therapy
after
healthcare
monitoring.
Meanwhile,
can
be
triggered
softened
partly
dissociated
under
prolonged
NIR
light
irradiation
transformation
temperature‐sensitive
low‐melting‐point
Agar
into
sol
state
partial
loaded
on
demand
synergistically
sterilizing
bacteria
efficiently
promoting
healing.
Hydrogel-enabled
skin
bioelectronics
that
can
continuously
monitor
health
for
extended
periods
is
crucial
early
disease
detection
and
treatment.
However,
it
challenging
to
engineer
ultrathin
gas-permeable
hydrogel
sensors
self-adhere
the
human
long-term
daily
use
(>1
week).
Here,
we
present
a
~10-micrometer-thick
polyurethane
nanomesh-reinforced
sensor
continuous
high-quality
electrophysiological
monitoring
8
days
under
life
conditions.
This
research
involves
two
key
steps:
(i)
material
design
by
gelatin-based
thermal-dependent
phase
change
hydrogels
(ii)
robust
thinness
geometry
achieved
through
nanomesh
reinforcement.
The
resulting
exhibit
thickness
of
~10
micrometers
with
superior
mechanical
robustness,
high
adhesion,
gas
permeability,
anti-drying
performance.
To
highlight
potential
applications
in
treatment
leverage
collective
features,
demonstrate
long-term,
high-precision
conditions
up
days.
Advanced Materials,
Год журнала:
2022,
Номер
35(10)
Опубликована: Дек. 28, 2022
Abstract
Real‐time
monitoring
of
human
health
can
be
significantly
improved
by
designing
novel
electronic
skin
(E‐skin)
platforms
that
mimic
the
characteristics
and
sensitivity
skin.
A
high‐quality
E‐skin
platform
simultaneously
monitor
multiple
physiological
metabolic
biomarkers
without
introducing
discomfort
or
irritation
is
an
unmet
medical
need.
Conventional
E‐skins
are
either
monofunctional
made
from
elastomeric
films
do
not
include
key
synergistic
features
natural
skin,
such
as
multi‐sensing,
breathability,
thermal
management
capabilities
in
a
single
patch.
Herein,
biocompatible
biodegradable
patch
based
on
flexible
gelatin
methacryloyl
aerogel
(FGA)
for
non‐invasive
continuous
interest
engineered
demonstrated.
Taking
advantage
cryogenic
temperature
treatment
slow
polymerization,
FGA
fabricated
with
highly
interconnected
porous
structure
displays
good
flexibility,
passive‐cooling
capabilities,
ultra‐lightweight
properties
make
it
comfortable
to
wear
long
periods
time.
It
also
provides
numerous
permeable
capillary
channels
thermal‐moisture
transfer,
ensuring
its
excellent
breathability.
Therefore,
FGA‐based
body
temperature,
hydration,
biopotentials
via
electrophysiological
sensors
detect
glucose,
lactate,
alcohol
levels
electrochemical
sensors.
This
work
offers
previously
unexplored
materials
strategy
next‐generation
superior
practicality.
