A long road ahead to reliable and complete medicinal plant genomes DOI Creative Commons

L. Cheng,

Zilong Wang, Qian‐Hao Zhu

и другие.

Nature Communications, Год журнала: 2025, Номер 16(1)

Опубликована: Март 4, 2025

Язык: Английский

Hemp: A Sustainable Plant with High Industrial Value in Food Processing DOI Creative Commons
Hiroyuki Yano, Wei Fu

Foods, Год журнала: 2023, Номер 12(3), С. 651 - 651

Опубликована: Фев. 2, 2023

In the era of SDGs, useful plants which provide valuable industrial outputs and at same time pose less impact on environment should be explored. Hemp seems one most relevant gluten-free crop to meet such requirements. Its high nutritional value is comparable soy. Moreover, almost whole body hemp plant has a wide array utility: production food, fiber, construction materials. view environmental sustainability, requires pesticides or water in cultivation compared cotton, representative fiber plant. This short review investigates hemp’s sustainability as well its utility highly material food industry. Recent application research protein processing includes milk, emulsifiers, fortification bread, plant-based meat production, membrane formation. These studies have revealed distinctive properties protein, especially relation disulfide (S-S)/sulfhydryl (-SH)-mediated interactions with from other sources. While area use were limited for while over confusion marijuana, market growing rapidly because it been reevaluated multiple areas Conclusively, property seed promising development new foods.

Язык: Английский

Процитировано

61

Cannabis: a multifaceted plant with endless potentials DOI Creative Commons
Eric Fordjour, Charles F. Manful,

Albert Adu Sey

и другие.

Frontiers in Pharmacology, Год журнала: 2023, Номер 14

Опубликована: Июнь 15, 2023

Cannabis sativa , also known as “hemp” or “weed,” is a versatile plant with various uses in medicine, agriculture, food, and cosmetics. This review attempts to evaluate the available literature on ecology, chemical composition, phytochemistry, pharmacology, traditional uses, industrial toxicology of . So far, 566 compounds have been isolated from including 125 cannabinoids 198 non-cannabinoids. The psychoactive physiologically active part cannabinoid, mostly found flowers, but present smaller amounts leaves, stems, seeds. Of all phytochemicals, terpenes form largest composition plant. Pharmacological evidence reveals that plants contain which exhibit potential antioxidants, antibacterial agents, anticancer anti-inflammatory agents. Furthermore, reported applications food cosmetic industries. Significantly, cultivation has minimal negative impact environment terms cultivation. Most studies focused make-up, pharmacological effects, not much about toxic effects. Overall, enormous for biological well other medicinal uses. However, further research necessary fully understand explore beneficial properties

Язык: Английский

Процитировано

49

A second update to the checklist of the vascular flora alien to Italy DOI
Gabriele Galasso, Fabio Conti, Lorenzo Peruzzi

и другие.

Plant Biosystems - An International Journal Dealing with all Aspects of Plant Biology, Год журнала: 2024, Номер 158(2), С. 297 - 340

Опубликована: Март 3, 2024

Critical and updated alien species inventories are crucial to properly manage contrast biological invasions. After 6 years, a second update the inventory of vascular flora Italy is presented. It provides details on occurrence at administrative regional level and, for first time, floristic data San Marino. The checklist includes 1782 taxa (1673 species, 28 subspecies, 69 hybrids 12 cultivar groups not attributable specific binomial), distributed in 786 genera 159 families; 2 lycophytes, 13 ferns fern allies, 37 gymnosperms 1730 angiosperms. Among these, 154 archaeophytes 1628 neophytes. currently established 899 (649 naturalized 250 invasive), while 796 casual aliens, 1 assessed, 38 have been confirmed recent times, 4 considered extinct or possibly country, 40 doubtfully occurring Italy, unknown distribution 110 reported by mistake be excluded national level. This allows establish an up-to-date number (10,023) constituting whole (either native alien) Italian flora.

Язык: Английский

Процитировано

46

Medicinal plants meet modern biodiversity science DOI Creative Commons
Charles C. Davis, Patrick Choisy

Current Biology, Год журнала: 2024, Номер 34(4), С. R158 - R173

Опубликована: Фев. 1, 2024

Plants have been an essential source of human medicine for millennia. In this review, we argue that a holistic, interdisciplinary approach to the study medicinal plants combines methods and insights from three key disciplines - evolutionary ecology, molecular biology/biochemistry, ethnopharmacology is poised facilitate new breakthroughs in science, including pharmacological discoveries rapid advancements health well-being. Such research leverages data spanning space, time, species associated with plant evolution, genomics, metabolomic trait diversity, all which build heavily on traditional Indigenous knowledge. contrasts sharply most well-funded successful during last half-century, which, despite notable advancements, has greatly oversimplified dynamic relationships between humans, kept hidden larger narratives about these relationships, overlooked potentially important into life-saving medicines. We suggest people should be viewed as partners whose relationship involves complicated poorly explored set (socio-)ecological interactions not only domestication but also commensalisms mutualisms. short, are just chemical factories extraction exploitation. Rather, they may symbiotic shaped modern societies, improved health, extended lifespans.

Язык: Английский

Процитировано

31

G-quadruplex DNA: a novel target for drug design DOI
Fangyuan Teng, Zongzhe Jiang, Man Guo

и другие.

Cellular and Molecular Life Sciences, Год журнала: 2021, Номер 78(19-20), С. 6557 - 6583

Опубликована: Авг. 30, 2021

Язык: Английский

Процитировано

91

Cannabis Glandular Trichomes: A Cellular Metabolite Factory DOI Creative Commons

Cailun A. S. Tanney,

Rachel Backer, Anja Geitmann

и другие.

Frontiers in Plant Science, Год журнала: 2021, Номер 12

Опубликована: Сен. 20, 2021

Cannabis has been legalized for recreational use in several countries and medical is authorized an expanding list of countries; markets are growing internationally, causing increase demand high quality products with well-defined properties. The key compounds plants cannabinoids, which produced by stalked glandular trichomes located on female flowers. These produce resin that contains such as tetrahydrocannabinolic acid cannabidiolic acid, array other secondary metabolites varying degrees commercial interest. While growers tend to focus improving whole flower yields, our understanding the “goldmines” plant – limited despite their being true source revenue a multi-billion-dollar industry. This review aims provide overview current cannabis metabolite order identify gaps knowledge outline future research directions.

Язык: Английский

Процитировано

74

Developing and Testing Molecular Markers in Cannabis sativa (Hemp) for Their Use in Variety and Dioecy Assessments DOI Creative Commons
Marcello Borin, Fabio Palumbo, Alessandro Vannozzi

и другие.

Plants, Год журнала: 2021, Номер 10(10), С. 2174 - 2174

Опубликована: Окт. 14, 2021

Cannabis sativa (2n = 2x 20) is a popular species belonging to the Cannabaceae family. Despite its use for medical, recreational, and industrial purposes as well long history, genetic research on this in infancy due legal implications prohibition campaigns. The recent legalization of many countries along with genomics boosted approaches aimed at marker-assisted selection, germplasm management, discrimination, authentication cultivars. Nonetheless, exploitation molecular markers development commercial varieties through breeding schemes still rare. present study develop an informative panel simple sequence repeat be used genotyping high value C. lines. Starting from 41 nuclear SSR designated by silico analyses, we selected 20 highly polymorphic discriminant loci that were tested 104 individuals 11 distinct hemp varieties. successful accessing homozygosity, uniformity, variation within among Population structure analysis identified eight groups, clustering based sexual behaviors (dioecious monoecious) geographical origins. Overall, provides important tools characterization, authentication, conservation biodiversity, improvement traceability increasingly plant species.

Язык: Английский

Процитировано

68

Parallel evolution of cannabinoid biosynthesis DOI
Paula Berman, Luis Alejandro de Haro, Adam Jóźwiak

и другие.

Nature Plants, Год журнала: 2023, Номер 9(5), С. 817 - 831

Опубликована: Май 1, 2023

Язык: Английский

Процитировано

39

Plant genome resequencing and population genomics: Current status and future prospects DOI Creative Commons
Bo Song, Weidong Ning, Di Wei

и другие.

Molecular Plant, Год журнала: 2023, Номер 16(8), С. 1252 - 1268

Опубликована: Июль 27, 2023

Advances in DNA sequencing technology have sparked a genomics revolution, driving breakthroughs plant genetics and crop breeding. Recently, the focus has shifted from cataloging genetic diversity plants to exploring their functional significance delivering beneficial alleles for improvement. This transformation been facilitated by increasing adoption of whole-genome resequencing. In this review, we summarize current progress population-based genome resequencing studies how these affect A total 187 land 163 countries resequenced, comprising 54 413 accessions. As part efforts 367 traits surveyed 86 genome-wide association conducted. Economically important crops, particularly cereals, vegetables, legumes, dominated efforts, leaving gap 49 orders, including Lycopodiales, Liliales, Acorales, Austrobaileyales, Commelinales. The resequenced germplasm is distributed across diverse geographic locations, providing global perspective on genomics. We highlight genes that selected during domestication, or associated with agronomic traits, form repository candidate future research application. Despite opportunities cross-species comparative genomics, many population genomic datasets are not accessible, impeding secondary analyses. call more open collaborative approach promotes data sharing encourages contribution-based credit policy. number will continue rise decreasing costs, coupled advances analysis computational technologies. expansion, terms both scale quality, holds promise deeper insights into trait breeding design.

Язык: Английский

Процитировано

38

Review of the oral toxicity of cannabidiol (CBD) DOI Creative Commons

Jeremy Gingrich,

Supratim Choudhuri,

Patrick Cournoyer

и другие.

Food and Chemical Toxicology, Год журнала: 2023, Номер 176, С. 113799 - 113799

Опубликована: Апрель 22, 2023

Information in the published literature indicates that consumption of CBD can result developmental and reproductive toxicity hepatotoxicity outcomes animal models. The trend CBD-induced male has been observed phylogenetically disparate organisms, from invertebrates to non-human primates. also shown inhibit various cytochrome P450 enzymes certain efflux transporters, resulting potential for drug-drug interactions cellular accumulation xenobiotics are normally transported out cell. mechanisms CBD-mediated not fully understood, but they may involve disruption critical metabolic pathways liver enzyme functions, receptor-specific binding activity, testosterone steroidogenesis, inhibition reuptake degradation endocannabinoids, triggering oxidative stress. toxicological profile raises safety concerns, especially long term by general population.

Язык: Английский

Процитировано

26