Advanced functional chitosan-based nanocomposite materials for performance-demanding applications DOI Creative Commons
Yabin Guo,

Dongling Qiao,

Siming Zhao

и другие.

Progress in Polymer Science, Год журнала: 2024, Номер 157, С. 101872 - 101872

Опубликована: Авг. 26, 2024

• Chitosan-based nanocomposites for biomedical and other applications reviewed. Nanofillers (e.g. clays, CNTs, graphene, MXene) add new functions to chitosan. Strategies modify chitosan nanofillers functional discussed. Functional properties antimicrobial, adhesive, stimulus-responsive) Chitosan holds great promise demanding such as packing uses. There has been a notable increase in interest combining or its derivatives with polymers achieve synergistic effects. Remarkable progress made through polymer molecular design iterative nanotechnology the development of chitosan-based nanocomposite materials tailored high-performance applications. This review focuses on strategies develop materials, highlighting advantages disadvantages modification critically evaluating various fabrication methods. Following brief introduction their functionalization, this discusses (e.g., mechanical, thermal, water resistance, gas-barrier, stimulus-response, shape memory, biological, electrochemical, corrosion-protection, antifouling, abruption/desorption) systems. It then highlights emerging potential fields packaging, biomedicine, 3D bioprinting, sensing wearable devices, environmental remediation, chemical engineering. Moreover, we explore factors that hinder commercialization nanocomposites. Our not only surveys recent advancements engineering sophisticated customized diverse array applications, but also offers insights into future formulation multifaceted nanocomposites, poised tackle distinct demands hurdles encountered burgeoning

Язык: Английский

Wound management materials and technologies from bench to bedside and beyond DOI
Canran Wang, Ehsan Shirzaei Sani, Chia-Ding Shih

и другие.

Nature Reviews Materials, Год журнала: 2024, Номер 9(8), С. 550 - 566

Опубликована: Июнь 17, 2024

Язык: Английский

Процитировано

86
Articular cartilage repair biomaterials: strategies and applications DOI Creative Commons
Mingkai Wang, Yan Wu, Guangfeng Li

и другие.

Materials Today Bio, Год журнала: 2024, Номер 24, С. 100948 - 100948

Опубликована: Янв. 5, 2024

Articular cartilage injury is a frequent worldwide disease, while effective treatment urgently needed. Due to lack of blood vessels and nerves, the ability self-repair limited. Despite availability various clinical treatments, unfavorable prognoses complications remain prevalent. However, advent tissue engineering regenerative medicine has generated considerable interests in using biomaterials for articular repair. Nevertheless, there remains notable scarcity comprehensive reviews that provide an in-depth exploration strategies applications. Herein, we present overview primary bioactive substances from perspective repair cartilage. The include regeneration, substitution, immunization. We comprehensively delineate influence mechanically supportive scaffolds on cellular behavior, shedding light emerging scaffold technologies, including stimuli-responsive smart scaffolds, 3D-printed bionic scaffolds. Biologically active substances, factors, stem cells, extracellular vesicles (EVs), organoids, are elucidated their roles regulating activity chondrocytes. Furthermore, composite produced industrially put into use, also explicitly presented. This review offers innovative solutions treating ailments emphasizes potential translation.

Язык: Английский

Процитировано

61
Wireless and Closed‐Loop Smart Dressing for Exudate Management and On‐Demand Treatment of Chronic Wounds DOI
Zhenyou Ge,

Wenshang Guo,

Ye Tao

и другие.

Advanced Materials, Год журнала: 2023, Номер 35(47)

Опубликована: Авг. 7, 2023

Chronic wounds have become a significant threat to people's physical and mental health increased the burden of social medical care. Intelligent wound dressing (IWD) with condition monitoring closed-loop on-demand drug therapy can shorten healing process alleviate patient suffering. However, single-function dressings cannot meet current needs chronic treatment. Here, wearable IWD consisting exudate management, sensor monitoring, therapy, flexible circuit modules is reported, which achieve effective synergy between management therapy. The attached site, spontaneously pumped into microfluidic channel for storage. Meanwhile, detect state through temperature humidity sensor, use this as feedback control liquid metal (LM) heater smartphone, thereby realizing release from hydrogel. In mouse model infected wounds, accelerates by reducing inflammatory responses, promoting angiogenesis collagen deposition.

Язык: Английский

Процитировано

57
Advances in health rehabilitation devices based on triboelectric nanogenerators DOI
Yansong Gai, Yonggang Jiang, Zhou Li

и другие.

Nano Energy, Год журнала: 2023, Номер 116, С. 108787 - 108787

Опубликована: Авг. 15, 2023

Язык: Английский

Процитировано

44
The intrinsic impact of dielectric constant on output generation of triboelectric nanogenerators DOI Creative Commons

Rameesh Bulathsinghala,

A. Ravichandran,

Hongquan Zhao

и другие.

Nano Energy, Год журнала: 2024, Номер 123, С. 109383 - 109383

Опубликована: Фев. 11, 2024

Triboelectric Nanogenerators (TENG), which convert mechanical energy into electrical pulses, are envisioned to lead future harvesting and self-powered sensing applications in wearable IoT sectors. While optimisation of most parameters related TENG is well understood, the impact dielectric constant, fundamental their output generation, still a highly debated topic. The intrinsic constant on performance extremely difficult assess experimentally, as it closely associates with other like surface charge density that can alter outputs. Herein, for first time, we present study fully characterise First, theoretical methods used investigate outputs against increasing constant. A novel experimental technique introduced using an array liquid filler materials, providing unique pathway systematically tune without impacting parameters. This study, unveils load-dependent behaviour generation along several previously unreported trends. By tuning demonstrate up 122% (theoretical) 28% (experimental) increments power output, paving way enhanced optimisation.

Язык: Английский

Процитировано

21
High‐Performance Self‐Powered Flexible Thermoelectric Device for Accelerated Wound Healing DOI
Yuwei Zhang, Bangzhi Ge, Jianghe Feng

и другие.

Advanced Functional Materials, Год журнала: 2024, Номер 34(40)

Опубликована: Апрель 16, 2024

Abstract Electric signal accelerates full‐thickness wound healing in the clinic, which is usually generated by a large power generation system and requires delicate control authorized personnel. Here, self‐powered flexible biocompatible thermoelectric device with exceptionally high efficiency developed. It generates 10 mV voltage at temperature gradient of K, outperforming all reported devices. Accordingly, it can directly efficiently convert omnipresent heat skin to electricity microvolt level. The output activates upregulates expression Piezo1‐mediated pathways that are associated tissue regeneration, accelerating cell migration proliferation vitro 4 days faster vivo. Importantly, fast‐heals without involving any additional electric circuit such as an amplifier. These advantages will revolutionize designing wearable bioelectronics for diagnosing, monitoring, treating various pathological conditions employing heat.

Язык: Английский

Процитировано

21
The advancement of intelligent dressings for monitoring chronic wound infections DOI

Xiaofeng Wang,

Bowen Zhong, Zheng Lou

и другие.

Chemical Engineering Journal, Год журнала: 2024, Номер 484, С. 149643 - 149643

Опубликована: Фев. 17, 2024

Язык: Английский

Процитировано

19
Laser‐Induced Nanozyme Biofuel Cell‐Based Self‐Powered Patch for Accelerating Diabetic Wound Healing With Real‐Time Monitoring DOI Open Access

Chengcheng Gu,

Lei Zhang, Ting Hou

и другие.

Advanced Functional Materials, Год журнала: 2025, Номер unknown

Опубликована: Март 7, 2025

Abstract Chronic wounds are a common complication of diabetes, causing significant inconvenience, persistent pain, and economic burden to patients. Real‐time monitoring wound status timely treatment with intelligent dressings is promising way treat infection accelerate healing. However, the traditional make it difficult simultaneously maintain true state meet dynamic needs chronic wounds. Herein, multifunctional self‐powered patch (MSPP) featured antibacterial, hypoglycemic, electrical stimulation designed promote healing real‐time status, in which laser‐induced nanozyme electrodes prepared situ through laser scanning technology construct highly stable nanozyme‐based glucose biofuel cells (GBFCs). Enzymatic cascade reaction GBFCs can use local hyperglycemia produce reactive oxygen species effective antibacterial properties, reduce while generating microcurrent, further diabetes In just 10 days, patch‐treated group achieves 100% shrinkage. Meanwhile, pH sensing module MSPP also monitor fluctuations correct test results, improving accuracy. brief, construction provides solutions for developing closed‐loop biomedical systems that integrate monitoring, diagnosis, treatment.

Язык: Английский

Процитировано

5
Nanozyme-based wearable biosensors for application in healthcare DOI Creative Commons
Yingcong Zhang, Yiran Yang,

Zhixin Yin

и другие.

iScience, Год журнала: 2025, Номер 28(2), С. 111763 - 111763

Опубликована: Янв. 7, 2025

Recent years have witnessed tremendous advances in wearable sensors, which play an essential role personalized healthcare for their ability real-time sensing and detection of human health information. Nanozymes, capable mimicking the functions natural enzymes addressing limitations, possess unique advantages such as structural stability, low cost, ease mass production, making them particularly beneficial constructing recognition units biosensors. In this review, we aim to delineate latest advancements nanozymes development biosensors, focusing on key developments nanozyme immobilization strategies, technologies, biomedical applications. The review also highlights current challenges future perspectives. Ultimately, it aims provide insights research endeavors rapidly evolving area.

Язык: Английский

Процитировано

3
Metal-organic frameworks as thermocatalysts for hydrogen peroxide generation and environmental antibacterial applications DOI Creative Commons

Ajitesh Pal,

Sreerag Suresh, Arshad Khan

и другие.

Science Advances, Год журнала: 2025, Номер 11(2)

Опубликована: Янв. 8, 2025

Reactive oxygen species (ROS) are highly reactive, making them useful for environmental and health applications. Traditionally, photocatalysts piezocatalysts have been used to generate ROS, but their utilization is limited by various physical constraints. This study introduces metal-organic frameworks (MOFs) as modern thermocatalysts efficiently producing hydrogen peroxide (H 2 O ) from small temperature differences. Temperature fluctuations, abundant in daily life, offer tremendous potential practical thermocatalytic As proof of concept, MOF materials coated onto carbon fiber fabric (MOF@CFF) created a antibacterial filter. The compared three different MOFs (CuBDC, MOF-303, ZIF-8) with bismuth telluride (Bi Te 3 ), known material. ZIF-8 demonstrated superior H generation under low-temperature differences, achieving 96% activity through variation cycles. work advances thermoelectric applications MOFs, enabling real-time purification disinfection generation. findings open interdisciplinary avenues leveraging effects catalysis technologies.

Язык: Английский

Процитировано

3