Scientific Reports,
Год журнала:
2024,
Номер
14(1)
Опубликована: Ноя. 6, 2024
Abstract
The
increase
in
marine
diseases,
particularly
economically
important
mollusks,
is
a
growing
concern.
Among
them,
the
Pacific
oyster
(
Crassostrea
gigas
)
production
faces
challenges
from
several
such
as
Oyster
Mortality
Syndrome
(POMS)
or
vibriosis.
microbial
education,
which
consists
of
exposing
host
immune
system
to
beneficial
microorganisms
during
early
life
stages
promising
approach
against
diseases.
This
study
explores
concept
education
using
controlled
and
pathogen-free
bacterial
communities
assesses
its
protective
effects
POMS
Vibrio
aestuarianus
infections,
highlighting
potential
applications
production.
We
demonstrate
that
it
possible
educate
by
adding
larval
stage.
Adding
culture
based
mixes
larvae
protects
only
disease
while
whole
donors
both
efficiency
protection
depends
on
origin
composition
used
for
exposure.
No
preferential
was
observed
when
oysters
were
stimulated
with
their
sympatric
strains.
Furthermore,
added
bacteria
not
maintained
into
microbiota,
but
this
addition
induced
long
term
changes
microbiota
gene
expression.
Our
reveals
successful
introducing
improved
long-term
resistance
critical
diseases
(POMS
infections)
aquaculture.
Nature Communications,
Год журнала:
2025,
Номер
16(1)
Опубликована: Янв. 25, 2025
The
evolutionary
impact
of
epigenetic
variation
depends
on
its
transgenerational
stability
and
source
-
whether
genetically
determined,
environmentally
induced,
or
due
to
spontaneous,
genotype-independent
mutations.
Here,
we
evaluate
current
approaches
for
investigating
an
independent
role
epigenetics
in
evolution,
pinpointing
methodological
challenges.
We
further
identify
opportunities
arising
from
integrating
data
with
population
genetic
analyses
natural
populations.
Efforts
advance
quality,
study
design,
statistical
treatment
are
encouraged
consolidate
our
understanding
the
heritable
variation,
quantify
autonomous
potential
enrich
additional
layer
information.
Philosophical Transactions of the Royal Society B Biological Sciences,
Год журнала:
2024,
Номер
379(1901)
Опубликована: Март 18, 2024
The
Pacific
oyster
Crassostrea
gigas
lives
in
microbe-rich
marine
coastal
systems
subjected
to
rapid
environmental
changes.
It
harbours
a
diversified
and
fluctuating
microbiota
that
cohabits
with
immune
cells
expressing
gene
repertoire.
In
the
early
stages
of
development,
just
after
fertilization,
plays
key
role
educating
system.
Exposure
rich
microbial
environment
at
larval
stage
leads
an
increase
competence
throughout
life
oyster,
conferring
better
protection
against
pathogenic
infections
later
juvenile/adult
stages.
This
beneficial
effect,
which
is
intergenerational,
associated
epigenetic
remodelling.
At
juvenile
stages,
educated
system
participates
control
homeostasis.
particular,
fine-tuned
by
antimicrobial
peptides
acting
through
specific
synergistic
effects.
However,
this
balance
fragile,
as
illustrated
Oyster
Mortality
Syndrome,
disease
causing
mass
mortalities
oysters
worldwide.
disease,
weakening
defences
OsHV-1
µVar
virus
induces
dysbiosis
leading
fatal
sepsis.
review
illustrates
continuous
interaction
between
highly
its
dynamic
life,
importance
cross-talk
for
health.
article
part
theme
issue
‘Sculpting
microbiome:
how
host
factors
determine
respond
colonization’.
Environmental Science & Technology,
Год журнала:
2024,
Номер
58(4), С. 1865 - 1876
Опубликована: Янв. 13, 2024
Marine
organisms
are
threatened
by
the
presence
of
pesticides
in
coastal
waters.
Among
them,
Pacific
oyster
is
one
most
studied
invertebrates
marine
ecotoxicology
where
numerous
studies
highlighted
multiscale
impacts
pesticides.
In
past
few
years,
a
growing
body
literature
has
reported
epigenetic
outcomes
xenobiotics.
Because
DNA
methylation
an
mark
implicated
organism
development
and
meiotically
heritable,
it
raises
question
multigenerational
implications
xenobiotic-induced
alterations.
Therefore,
we
performed
exposure
to
environmentally
relevant
mixture
18
(nominal
sum
concentration:
2.85
μg·L
In
holobiont,
microbiota
is
known
to
play
a
central
role
on
the
health
and
immunity
of
its
host.
Then,
understanding
microbiota,
dynamic
according
environmental
conditions
link
would
help
react
potential
dysbiosis
aquacultured
species.
While
gut
highly
studied,
in
marine
invertebrates
hemolymph
often
set
aside
even
if
it
remains
an
important
actor
homeostasis.
Indeed,
harbors
factors
involved
animal
homeostasis
that
interacts
with
immunity.
Southwest
Pacific,
high
economical
valued
shrimp
Penaeus
stylirostris
reared
two
contrasted
sites,
New
Caledonia
(NC)
French
Polynesia
(FP).
We
characterized
active
inhabiting
shrimps
while
considering
stability
during
seasons
at
one-month
interval
evidenced
microbial
variability
between
rearing
sites.
highlighted
specific
biomarkers
along
common
core
composed
6
ASVs.
Putative
functions
were
mostly
associated
bacterial
competition,
infections
metabolism
NC,
they
cell
FP
suggesting
site
discrimination.
Differential
relative
expression
immune
effectors
measured
populations
from
NC
FP,
exhibited
higher
level
compared
FP.
addition,
differential
was
correlated
based
their
geographical
location.
Our
data
suggest
that,
Pacific
shrimps,
both
could
have
undergone
immunostimulation
as
well
adaptative
divergence
Further,
identification
proxies
such
biomarkers,
be
used
guide
future
actions
monitor
thus
preserve
productions.
bioRxiv (Cold Spring Harbor Laboratory),
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 7, 2025
Abstract
Ostreid
herpesvirus
1
(OsHV-1)
poses
a
significant
threat
to
the
global
oyster
farming
industry,
causing
substantial
economic
losses
due
mortality
outbreaks.
While
OsHV-1
primarily
affects
Pacific
Magallana
gigas
,
it
has
been
linked
events
in
various
host
species.
Despite
advancements
understanding
epidemiology,
knowledge
gaps
persist
regarding
its
evolutionary
mechanisms
and
adaptation
genetic
backgrounds.
This
study
employs
experimental
evolution
extensive
genomic
analysis
unravel
dynamics
of
response
variation.
Our
results
show
that
mutations,
particularly
transitions
transversions,
played
role
shaping
viral
population,
leading
trend
toward
homogenization.
Stronger
positive
selection
signals
were
observed
population
with
higher
susceptibility,
suggesting
genotypes
specific
These
findings
shed
light
on
complex
interactions
hosts.
Understanding
how
this
virus
adapts
diversity
is
crucial
for
developing
strategies
mitigate
impact
industry
provides
valuable
insights
into
broader
