Journal of Neuroscience,
Год журнала:
2016,
Номер
36(31), С. 8038 - 8049
Опубликована: Авг. 3, 2016
Early
work
stressed
the
differing
involvement
of
central
amygdala
(CeA)
and
bed
nucleus
stria
terminalis
(BNST)
in
genesis
fear
versus
anxiety,
respectively.
In
2009,
Walker,
Miles,
Davis
proposed
a
model
amygdala-BNST
interactions
to
explain
these
functional
differences.
This
became
extremely
influential
now
guides
new
wave
studies
on
role
BNST
humans.
Here,
we
consider
evidence
for
against
this
model,
process
highlighting
principles
organization.
analysis
leads
us
conclude
that
BNST9s
influence
is
not
limited
generation
anxiety-like
responses
diffuse
threats,
but
it
also
shapes
impact
discrete
threatening
stimuli.
It
likely
BNST-CeA
are
involved
modulating
such
threats.
addition,
whereas
current
views
emphasize
contributions
anterolateral
region
accumulating
data
indicate
anteromedial
anteroventral
regions
play
critical
role.
The
presence
multiple
subregions
within
small
volume
raises
significant
technical
obstacles
imaging
American Psychologist,
Год журнала:
2016,
Номер
71(8), С. 670 - 679
Опубликована: Ноя. 1, 2016
Rewards
are
both
"liked"
and
"wanted,"
those
2
words
seem
almost
interchangeable.
However,
the
brain
circuitry
that
mediates
psychological
process
of
"wanting"
a
particular
reward
is
dissociable
from
degree
to
which
it
"liked."
Incentive
salience
or
"wanting,"
form
motivation,
generated
by
large
robust
neural
systems
include
mesolimbic
dopamine.
By
comparison,
"liking,"
actual
pleasurable
impact
consumption,
mediated
smaller
fragile
systems,
not
dependent
on
The
incentive-sensitization
theory
posits
essence
drug
addiction
be
excessive
amplification
specifically
especially
triggered
cues,
without
necessarily
an
"liking."
This
because
long-lasting
changes
in
dopamine-related
motivation
susceptible
individuals,
called
"neural
sensitization."
A
quarter-century
after
its
proposal,
evidence
has
continued
grow
support
theory.
Further,
scope
now
expanding
diverse
behavioral
addictions
other
psychopathologies.
(PsycINFO
Database
Record
