Mechanistic understanding of the toxic effects of arsenic and warfare arsenicals on human health and environment

Cell Biology and Toxicology, Год журнала: 2022, Номер 39(1), С. 85 - 110

Опубликована: Апрель 1, 2022

Abstract Worldwide, more than 200 million people are estimated to be exposed unsafe levels of arsenic. Chronic exposure groundwater arsenic is responsible for multiple human disorders, including dermal, cardiovascular, neurological, pulmonary, renal, and metabolic conditions. Consumption rice seafood (where high accumulated) also The toxicity compounds varies greatly may depend on their chemical form, solubility, concentration. Surprisingly, synthetic organoarsenicals extremely toxic molecules which created interest in development as warfare agents (CWAs) during World War I (WWI). Among these CWAs, adamsite, Clark I, II, lewisite critical importance, stockpiles still exist worldwide. In addition, unused WWII weaponized arsenicals discarded water bodies or buried many parts the world continue pose a serious threat environment health. Metabolic inhibition, oxidative stress, genotoxicity, epigenetic alterations micro-RNA-dependent regulation some underlying mechanisms toxicity. Mechanistic understanding effective therapeutic interventions. This review provides comprehensive details assessment recently published data various forms arsenic, exposure, implications environmental Graphical abstract

Язык: Английский

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Arsenic and other geogenic contaminants in global groundwater

Nature Reviews Earth & Environment, Год журнала: 2024, Номер 5(4), С. 312 - 328

Опубликована: Март 12, 2024

Язык: Английский

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Environmental behavior, human health effect, and pollution control of heavy metal(loid)s toward full life cycle processes

Eco-Environment & Health, Год журнала: 2022, Номер 1(4), С. 229 - 243

Опубликована: Ноя. 29, 2022

Heavy metal(loid)s (HMs) have caused serious environmental pollution and health risks. Although the past few years witnessed achievements of studies on behavior HMs, related toxicity mechanisms, control, their relationship remains a mystery. Researchers generally focused one topic independently without comprehensive considerations due to knowledge gap between science human health. Indeed, full life cycle control HMs is crucial should be reconsidered with combination occurrence, transport, fate in environment. Therefore, we started by reviewing behaviors which are affected variety natural factors as well physicochemical properties. Furthermore, mechanisms were discussed according exposure route, mechanism, adverse consequences. In addition, current state-of-the-art available technologies for wastewater solid wastes summarized. Finally, based research trend, proposed that advanced in-operando characterizations will help us better understand fundamental reaction big data analysis approaches aid establishing prediction model risk management.

Язык: Английский

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A review on different arsenic removal techniques used for decontamination of drinking water

Environmental Pollutants and Bioavailability, Год журнала: 2023, Номер 35(1)

Опубликована: Янв. 19, 2023

Arsenic (As) contamination is one of the most serious forms environmental pollution caused by human activities. Numerous concerned authorities around world are now focusing on As decontamination. The technologies for removing have grown in importance since it understood that even very low amounts drinking water can negative effects health. This review provides a thorough explanation various well-established and cutting-edge technologies, including ion exchanges, adsorption, membrane process, electrokinetic processes, electrocoagulation, precipitation, phytoremediation, inexpensive useful methods, emerging remedial techniques, nanoparticles nano based adsorbents be used to remove impurities from water. cost, simplicity easy operational mechanism adsorption technique gained much attention globally, however, also believed nanotechnology will essential supplying clean, suit needs.

Язык: Английский

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Deep learning for water quality

Nature Water, Год журнала: 2024, Номер 2(3), С. 228 - 241

Опубликована: Март 12, 2024

Язык: Английский

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