Advanced Functional Materials,
Год журнала:
2024,
Номер
unknown
Опубликована: Сен. 29, 2024
Abstract
Ionogels
are
considered
as
ideal
candidates
for
constructing
flexible
electronics
due
to
their
superior
electrical
conductivity,
flexibility,
high
thermal
and
electrochemical
stability.
However,
it
remains
a
great
challenge
simultaneously
achieve
sensitivity,
repeated
adhesion,
good
self‐healing,
biocompatibility
through
straightforward
strategy.
Herein,
inspired
by
nucleobase‐tackified
strategy,
multifunctional
adhesive
ionogel
is
developed
one‐step
radical
polymerization
of
acrylated
adenine/uracil
(Aa/Ua)
acrylic
acid
(AA)
monomers
in
sodium
caseinate
(SC)
stabilized
liquid
metal
dispersions.
As
soft
conductive
filler,
the
incorporating
not
only
improves
but
also
enhances
mechanical
strength,
satisfying
stretchable
sensing
application.
The
large
amount
noncovalent
interactions
(hydrogen
bonding,
coordination,
ion‐dipole
interactions)
within
networks
enable
ionogels
possess
excellent
stretchability,
skin‐like
softness,
strong
adhesion.
Based
on
these
desirable
characteristics,
suitable
wearable
strain
sensors
precisely
detect
diverse
human
movements
under
extreme
environments.
Moreover,
seamless
adhesion
with
skin
allows
function
bioelectrode
patch
long‐term
high‐quality
electrophysiological
signal
acquisition.
This
research
provides
promising
strategy
designing
tailored
functionalities
that
satisfy
application
requirements.
Achieving
high-quality
biopotential
signal
recordings
requires
soft
and
stable
interfaces
between
tissues
bioelectronic
devices.
Traditional
bioelectronics,
typically
rigid
dependent
on
medical
tape
or
sutures,
lead
to
mechanical
mismatches
inflammatory
responses.
Existing
conducting
polymer-based
bioelectronics
offer
tissue-like
softness
but
lack
intrinsic
adhesion,
limiting
their
effectiveness
in
creating
stable,
conductive
interfaces.
Here,
we
present
an
intrinsically
adhesive
hydrogel
with
a
modulus
strong
adhesion
various
substrates.
Adhesive
catechol
groups
are
incorporated
into
the
poly(3,4-ethylenedioxythiophene)
(PEDOT)
matrix,
which
reduces
PEDOT
size
improves
dispersity
form
percolating
network
excellent
electrical
conductivity
strain
insensitivity.
This
effectively
bridges
bioelectronics–tissue
interface,
ensuring
pristine
minimal
interference
from
bodily
movements.
capability
is
demonstrated
through
comprehensive
vivo
experiments,
including
electromyography
electrocardiography
both
static
dynamic
human
skin
electrocorticography
moving
rats.
represents
significant
advancement
for
interfaces,
facilitating
more
accurate
less
intrusive
diagnostics.
Advanced Materials,
Год журнала:
2025,
Номер
unknown
Опубликована: Март 13, 2025
Abstract
Flexible
bioelectronic
interfaces
with
adhesive
properties
are
essential
for
advancing
modern
medicine
and
human‐machine
interactions.
However,
achieving
both
stable
adhesion
non‐damaging
detachment
remains
a
significant
challenge.
In
this
study,
lithium
bond‐mediated
molecular
cascade
hydrogel
(LMCH)
is
designed,
which
facilitates
robust
at
the
tissue
level
permits
atraumatic
repositioning
as
required.
By
integrating
of
structure
elastic
characteristics
interface,
LMCH
interface
not
only
achieved
high
strength
(197
J
m
−2
)
on
skin,
but
also
significantly
extended
cracking
cycles
surface
during
peeling
process
from
4
to
380,
marking
an
enhancement
nearly
two
orders
magnitude.
Furthermore,
Young's
modulus
similar
that
human
(25
kPa),
exceptional
stretchability
(1080%),
ionic
conductivity
(7.14
S
−1
),
demonstrates
outstanding
compatibility,
biocompatibility,
detection
capabilities
electrocardiogram
(ECG)
electromyogram
(EMG)
signals.
This
study
presents
new
insights
potential
bioelectronics
implantable
technologies.
Advanced Functional Materials,
Год журнала:
2024,
Номер
unknown
Опубликована: Ноя. 22, 2024
Abstract
Collecting
electrophysiological
(EP)
signals
(e.g.,
electrocardiogram
(ECG),
electromyogram
(EMG))
during
exercises
is
crucial
for
feedback
of
cardiac
health
and
muscle
injuries.
However,
since
several
interferences
exist
in
the
skin
interface
deformation,
perspiration,
motion
artifacts),
commercial
rigid
electrodes/systems
have
difficulty
recording
high‐fidelity
EP
signals.
Here,
a
wireless
Nepenthes
‐inspired
hydrogel
(NIH)
hybrid
system
developed
high‐quality
signal
detection
by
establishing
seamless‐integrated
rapidly
directional
sweat‐wicking
device/skin
interfaces
exercises.
The
adhesive
strength
poly(vinyl
alcohol)/poly(acrylic
acid)
(PVA/PAAC)‐based
double‐network
hydrogels
significantly
increased
more
than
sixfolds.
microstructures
are
further
fabricated
on
to
enhance
transport
speed
droplets
4.5
times.
Notably,
NIH
electrodes
can
maintain
an
intimate
coupling
with
continuous
artificial
sweat
injection
while
showing
lowest
impedance
highest
signal‐to‐noise
ratio
(>19
dB)
EMG
under
complex
conditions
(i.e.,
vibration
perspiration).
Finally,
decorating
silicone
joints
hollow
structures
avoid
stress
concentration.
This
record
ECG
waveforms
heart
rate
curves
relative
deviations
<2.6%
rest.
represents
promising
platform
precise
monitoring
exercising
scenarios.
Advanced Science,
Год журнала:
2025,
Номер
unknown
Опубликована: Март 16, 2025
Abstract
Lactobacillus
reuteri
(
L.
)
therapies
represent
a
potentially
effective
approach
to
eradicating
Helicobacter
pylori
(H.
pylori)
.
However,
the
difficulty
in
bacterial
viability
preservation
and
harsh
gastric
environment
compromises
survival
on‐target
delivery
of
This
study
presents
novel
bacterium‐mediated
elimination
strategy
using
an
edible
@HTP
probiotic
powder
for
targeted
elimination.
The
is
obtained
by
grinding
lyophilized
hydrogel
composed
,
hyaluronic
acid
(HA),
tannic
(TA),
polyvinyl
alcohol
(PVA).
Upon
contact
with
water,
quickly
transforms
into
hydrogel,
enhancing
’s
ensuring
selective
release
at
H.
‐infected
inflammatory
sites.
targets
reduces
colonization
while
secreting
reuterin
eliminate
bacteria.
Additionally,
TA's
antioxidant
properties
help
alleviate
inflammation,
HA
supports
mucosal
repair.
preserves
integrity
gut
microbiota,
facilitating
restoration
healthy
microbiome.
In
particular,
remains
stable
room
temperature
least
six
months,
providing
promising
alternative
traditional
antibiotics
treatment.
combines
eradication,
healing,
microbiome
restoration,
offering
new
treating
infections.
