Frontiers in Microbiology,
Journal Year:
2025,
Volume and Issue:
16
Published: April 23, 2025
The
demand
for
early
disease
detection,
treatment
monitoring,
and
personalized
medicine
is
increasing,
making
it
more
imperative
than
ever
to
create
effective,
accurate,
portable,
intelligent,
multifunctional
diagnostic
equipment.
Bacteria
possess
a
remarkable
perception
of
their
surroundings
have
the
capacity
adapt
by
altering
expression
specific
genes.
interact
with
target
substances
produce
detectable
signals
in
response
presence
or
concentration.
This
unique
property
has
been
harnessed
development
bacterial
biosensors.
Due
groundbreaking
advancements
synthetic
biology,
genetic
engineering
now
enables
creation
bacteria
tailored
exceptional
detecting
traits.
In
addition
meeting
wide
range
application
needs,
this
allows
quick
precise
detection
intricate
settings
offers
strong
technological
basis
diagnosis
monitoring.
article
reviews
applications
recent
biosensors
medical
field
discusses
challenges
obstacles
that
remain
research
application.
Advanced Functional Materials,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 26, 2025
Abstract
Auxetic
metamaterials
refer
to
materials
and
structures
with
extraordinary
deformation,
i.e.,
transverse
expansion
(contraction)
under
uniaxial
tension
(compression).
In
recent
decades,
a
very
wide
range
of
innovative
functional
performance
has
been
discovered
stemming
from
this
behavior.
This
desirable
exhibition
adaptivity,
programmability,
functionality
provides
great
potential
in
soft
intelligent
systems.
However,
thus
far,
the
mainstream
research
on
auxetic
focused
subjective
design,
monotonic
mechanical
properties,
passive
tunability.
review
thorough
overview
classical
properties
applications,
primary
objective
proposing
new
roadmap
auxetics
for
advances
interdisciplinary
field.
The
fundamental
works
are
categorized
different
configurations
mechanisms.
particular,
integration
shape
morphing,
actuation,
sensing,
multiphysical
response,
inverse
design
is
reviewed
detail.
To
accelerate
development
smart
structural
systems,
applications
generalized
into
robotics
(outside
body),
human–machine
interaction
(surrounding
healthcare
devices
(inside
body).
Finally,
several
significant
topics
emphasized
theory,
material
choice,
manufacturing
technique,
applications.
ACS Nano,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 23, 2025
Achieving
high-quality
biopotential
signal
recordings
requires
soft
and
stable
interfaces
between
tissues
bioelectronic
devices.
Traditional
bioelectronics,
typically
rigid
dependent
on
medical
tape
or
sutures,
lead
to
mechanical
mismatches
inflammatory
responses.
Existing
conducting
polymer-based
bioelectronics
offer
tissue-like
softness
but
lack
intrinsic
adhesion,
limiting
their
effectiveness
in
creating
stable,
conductive
interfaces.
Here,
we
present
an
intrinsically
adhesive
hydrogel
with
a
modulus
strong
adhesion
various
substrates.
Adhesive
catechol
groups
are
incorporated
into
the
poly(3,4-ethylenedioxythiophene)
(PEDOT)
matrix,
which
reduces
PEDOT
size
improves
dispersity
form
percolating
network
excellent
electrical
conductivity
strain
insensitivity.
This
effectively
bridges
bioelectronics–tissue
interface,
ensuring
pristine
minimal
interference
from
bodily
movements.
capability
is
demonstrated
through
comprehensive
vivo
experiments,
including
electromyography
electrocardiography
both
static
dynamic
human
skin
electrocorticography
moving
rats.
represents
significant
advancement
for
interfaces,
facilitating
more
accurate
less
intrusive
diagnostics.
Advanced Materials,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 13, 2025
Abstract
Flexible
bioelectronic
interfaces
with
adhesive
properties
are
essential
for
advancing
modern
medicine
and
human‐machine
interactions.
However,
achieving
both
stable
adhesion
non‐damaging
detachment
remains
a
significant
challenge.
In
this
study,
lithium
bond‐mediated
molecular
cascade
hydrogel
(LMCH)
is
designed,
which
facilitates
robust
at
the
tissue
level
permits
atraumatic
repositioning
as
required.
By
integrating
of
structure
elastic
characteristics
interface,
LMCH
interface
not
only
achieved
high
strength
(197
J
m
−2
)
on
skin,
but
also
significantly
extended
cracking
cycles
surface
during
peeling
process
from
4
to
380,
marking
an
enhancement
nearly
two
orders
magnitude.
Furthermore,
Young's
modulus
similar
that
human
(25
kPa),
exceptional
stretchability
(1080%),
ionic
conductivity
(7.14
S
−1
),
demonstrates
outstanding
compatibility,
biocompatibility,
detection
capabilities
electrocardiogram
(ECG)
electromyogram
(EMG)
signals.
This
study
presents
new
insights
potential
bioelectronics
implantable
technologies.
Advanced Functional Materials,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Nov. 22, 2024
Abstract
Collecting
electrophysiological
(EP)
signals
(e.g.,
electrocardiogram
(ECG),
electromyogram
(EMG))
during
exercises
is
crucial
for
feedback
of
cardiac
health
and
muscle
injuries.
However,
since
several
interferences
exist
in
the
skin
interface
deformation,
perspiration,
motion
artifacts),
commercial
rigid
electrodes/systems
have
difficulty
recording
high‐fidelity
EP
signals.
Here,
a
wireless
Nepenthes
‐inspired
hydrogel
(NIH)
hybrid
system
developed
high‐quality
signal
detection
by
establishing
seamless‐integrated
rapidly
directional
sweat‐wicking
device/skin
interfaces
exercises.
The
adhesive
strength
poly(vinyl
alcohol)/poly(acrylic
acid)
(PVA/PAAC)‐based
double‐network
hydrogels
significantly
increased
more
than
sixfolds.
microstructures
are
further
fabricated
on
to
enhance
transport
speed
droplets
4.5
times.
Notably,
NIH
electrodes
can
maintain
an
intimate
coupling
with
continuous
artificial
sweat
injection
while
showing
lowest
impedance
highest
signal‐to‐noise
ratio
(>19
dB)
EMG
under
complex
conditions
(i.e.,
vibration
perspiration).
Finally,
decorating
silicone
joints
hollow
structures
avoid
stress
concentration.
This
record
ECG
waveforms
heart
rate
curves
relative
deviations
<2.6%
rest.
represents
promising
platform
precise
monitoring
exercising
scenarios.
npj Flexible Electronics,
Journal Year:
2024,
Volume and Issue:
8(1)
Published: Aug. 2, 2024
Recently
electronic
tattoo
sensors
have
attracted
immense
interest
for
health
monitoring
mainly
due
to
their
higher
sensing
performance
than
conventional
dry
sensors,
owing
the
ultra-low
thickness
which
results
in
conformability
skin.
However,
is
worse
wet
sensors.
Further,
these
are
not
durable
and
reusable
when
free-standing
because
of
low
being
too
delicate.
Here,
we
report
a
remarkably
high-performance
freestanding,
reusable,
ultrathin
ultra-soft
sensor
made
parylene-hydrogel
double
layer
system
with
high
water
retention
over
extended
periods
that
can
be
used
period
6
months.
The
hydrogel
(HET)
consist
electrically
conductive
self-adhesive
20
µm
Young's
modulus
only
31
kPa
at
37
°C,
allowing
ultra-conformal
contact
skin
microscopic
features.
Our
HET
fabricated
using
scalable
cost-effective
method
on
ordinary
papers
laminated
like
temporary
tattoos
were
electrophysiological
signals
recording
such
as
electrocardiography
(ECG),
electromyography
(EMG),
hydration,
temperature
sensing.
first
time,
show
234%
lower
sensor-skin
interface
impedance
(SSII)
significantly
susceptibility
motion
gold
standard
medical
grade
silver/silver
chloride
gel
electrodes
known
lowest
SSII
motion.
HET-skin
leads
considerably
larger
signal
amplitude
signal-to-noise
ratio
(SNR)
recorded
comparison
those
obtained
electrodes.
SNR
some
types
EMG
up
19
dB
amplitude,
artifacts.
Also,
transferred
from
paper
vice
versa
many
times
quality
remained
during
repeated
use
