Modulating Positive Self-Referential Processing by 40 Hz tACS in Individuals with Subthreshold Depression: A double-blind, sham-controlled study

Journal of Psychiatric Research, Год журнала: 2025, Номер unknown

Опубликована: Апрель 1, 2025

Язык: Английский

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Gamma Transcranial Alternating Current Stimulation Enhances Working Memory Ability in Healthy People: An EEG Microstate Study

Brain Sciences, Год журнала: 2025, Номер 15(4), С. 381 - 381

Опубликована: Апрель 7, 2025

Working memory (WM) is a core cognitive function closely linked to various processes including language, decision making, and reasoning. Transcranial alternating current stimulation (tACS), non-invasive brain technique, has been shown modulate abilities treat psychiatric disorders. Although gamma tACS (γ-tACS) demonstrated positive effects on WM, its underlying neural mechanisms remain unclear. In this study, we employed electroencephalogram (EEG) microstate analysis investigate the spatiotemporal dynamics of γ-tACS WM performance. Healthy participants (N = 104) participated in two-back three-back tasks before after two types (sine triangular) γ-tACS, with sham as control. Our results revealed that improved performance both tasks, triangular showing greater accuracy improvement task than group. Furthermore, significantly modulated EEG dynamics, specifically downregulating Class C upregulating Classes D B. These changes were positively correlated reduced reaction times task. findings establish an effective approach for evaluating γ-tACS-induced global activity advance understanding how influences WM.

Язык: Английский

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Gamma oscillatory transcranial direct current stimulation of motor cortex enhances corticospinal excitability and brain connectivity in healthy individuals

Cerebral Cortex, Год журнала: 2025, Номер 35(4)

Опубликована: Апрель 1, 2025

Abstract Cortical excitability, the tendency of neurons to respond various stimuli, is impaired in most neuropsychiatric conditions. Non-invasive brain stimulation can exert therapeutic effects by modulating cortical excitability. Transcranial direct current (tDCS) and transcranial alternating (tACS) have shown promise disorders, including improving cognitive abilities motor function following stroke. Oscillatory (otDCS), as a novel paradigm, combines tDCS tACS simultaneously regulate neuronal membrane potentials oscillatory rhythms. This combination may produce more significant on neurons. To investigate this, participants received stimuli for 20 min different days: (i) 2 mA 40 Hz otDCS, (ii) tACS, (iii) tDCS, (iv) sham stimulation. Motor evoked (MEPs) magnetic combined with electroencephalography (TMS-EEG) were assessed both before after The increase MEPs amplitudes was pronounced under otDCS conditions compared tDCS. Furthermore, analysis TMS-EEG data revealed that changes time-varying network patterns manifesting enhanced brain-wide information connectivity. Our results indicate gamma has potential regulating excitability activating networks.

Язык: Английский

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Harnessing theta waves: tACS as a breakthrough in alleviating post-stroke chronic pain

Frontiers in Neuroscience, Год журнала: 2025, Номер 19

Опубликована: Апрель 30, 2025

Neural oscillations play a critical role in the regulation of brain functions, with theta waves (4-8 Hz) sensorimotor cortex significantly influencing pain perception and modulation. These can modulate signal transmission, emotional cognition, neuroplasticity. Post-stroke chronic is common complex symptom that imposes significant physiological psychological burdens on patients. Transcranial alternating current stimulation (tACS), non-invasive technique, synchronize specific frequency neural activities, reorganize networks, neuroplasticity by adjusting oscillations. In recent years, tACS has been widely applied research treatment various neurological psychiatric disorders. This study aims to systematically summarize progress θ tACS. By reviewing relevant experimental clinical studies, we explore mechanisms modulation analyze effects Additionally, examine central peripheral post-stroke pain, emphasizing processing. conclusion, shows potential for modulating alleviating pain. provides new insights into related offers directions developing novel therapies. Future studies technological optimizations are necessary ensure effectiveness feasibility practice.

Язык: Английский

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Using non-invasive brain stimulation to modulate performance in visuomotor rotation adaptation: a scoping review

Cortex, Год журнала: 2025, Номер 187, С. 144 - 158

Опубликована: Май 1, 2025

Язык: Английский

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