Frontiers in Microbiomes,
Год журнала:
2024,
Номер
3
Опубликована: Дек. 4, 2024
This
review
focuses
on
the
role
of
microorganisms
in
promoting
health
and
immune
function
within
school
environments.
Microbes,
including
bacteria,
viruses,
fungi,
other
microorganisms,
constitute
human
microbiome
play
a
crucial
various
bodily
functions
system
development.
The
complex
interactions
between
schools,
where
children
spend
significant
amount
time,
are
not
fully
understood.
While
schools
have
traditionally
emphasized
hygiene
practices
to
prevent
spread
infectious
diseases,
recent
research
has
highlighted
potential
consequences
reduced
microbial
exposure
during
early
life.
“hygiene
hypothesis”
suggests
that
limited
microbes
infancy
may
increase
risk
allergies,
asthma,
autoimmune
diseases
adulthood.
paper
explores
diversity
found
benefits
different
implications
It
also
examines
current
intervention
strategies
their
influence
overall
schools.
Understanding
environments
for
public
policies
educational
practices,
aiming
create
healthier
more
conducive
learning
younger
generation.
By
comprehensively
exploring
this
topic,
contributes
broader
understanding
significance
settings
its
relevance
future
research.
Gastrointestinal Disorders,
Год журнала:
2025,
Номер
7(1), С. 7 - 7
Опубликована: Янв. 15, 2025
The
human
microbiome,
a
complex
ecosystem
of
microorganisms
residing
in
and
on
the
body,
plays
pivotal
role
regulation
wide
range
physiological
processes,
including
digestion,
immune
responses,
metabolic
functions.
In
recent
years,
rapidly
growing
field
microbiome-driven
therapeutics
has
garnered
significant
attention
owing
to
its
potential
revolutionize
healthcare.
This
review
explores
evolving
landscape
microbiome-based
therapies,
with
particular
focus
gut
microbiome
implications
for
both
health
precision
medicine.
We
highlight
advances
understanding
how
microbial
communities
influence
disease
pathogenesis
treatment
outcomes,
spanning
conditions
such
as
inflammatory
bowel
(IBD),
disorders,
neurological
diseases,
even
cancer.
article
also
discusses
emerging
therapeutic
strategies,
probiotics,
prebiotics,
fecal
microbiota
transplantation
(FMT),
microbial-based
drugs,
well
challenges
associated
their
clinical
implementation.
Additionally,
we
examined
integration
profiling
metagenomic
data
is
advancing
medicine,
paving
way
personalized
effective
treatments.
serves
comprehensive
resource
that
synthesizes
current
knowledge,
identifies
key
gaps
research,
offers
insights
into
future
direction
therapeutics,
thus
providing
valuable
framework
clinicians,
researchers,
policymakers
seeking
harness
microbiomes
advance
healthcare
solutions.
Allergy,
Год журнала:
2022,
Номер
77(12), С. 3498 - 3512
Опубликована: Июнь 24, 2022
Planetary
health
provides
a
perspective
of
ecological
interdependence
that
connects
the
and
vitality
individuals,
communities,
Earth's
natural
systems.
It
includes
social,
political,
economic
ecosystems
influence
both
individuals
whole
societies.
In
an
era
interconnected
grand
challenges
threatening
all
systems
at
scales,
planetary
framework
for
cross-sectoral
collaboration
unified
approaches
to
solutions.
The
field
allergy
is
forefront
these
efforts.
Allergic
conditions
are
sentinel
measure
environmental
impact
on
human
in
early
life-illuminating
how
changes
affect
immune
development
predispose
wider
range
inflammatory
noncommunicable
diseases
(NCDs).
This
shows
adverse
macroscale
ecology
Anthropocene
penetrates
molecular
level
personal
microscale
ecology,
including
microbial
foundations
ecosystems.
basis
more
integrated
efforts
address
widespread
degradation
effects
maladaptive
urbanization,
food
systems,
lifestyle
behaviors,
socioeconomic
disadvantage.
Nature-based
solutions
improve
nature-relatedness
crucial
restoring
symbiosis,
balance,
mutualism
every
sense,
recognizing
choices
collective
structural
actions
needed
tandem.
Ultimately,
meaningful
will
depend
placing
greater
emphasis
psychological
cultural
dimensions
such
as
mindfulness,
values,
moral
wisdom
ensure
sustainable
resilient
future.
npj Biofilms and Microbiomes,
Год журнала:
2023,
Номер
9(1)
Опубликована: Авг. 28, 2023
Abstract
Social
disparities
continue
to
limit
universal
access
health
care,
directly
impacting
both
lifespan
and
quality
of
life.
Concomitantly,
the
gut
microbiome
has
been
associated
with
downstream
outcomes
including
global
rise
in
antibiotic
resistance.
However,
limited
evidence
exists
examining
socioeconomic
status
(SES)
associations
composition.
To
address
this,
we
collected
information
on
community-level
SES,
microbiota,
other
individual
cofactors
colonization
by
multidrug-resistant
organisms
(MDROs)
an
adult
cohort
from
Wisconsin,
USA.
We
found
association
between
SES
microbial
composition
that
is
mediated
food
insecurity.
Additionally,
observed
a
higher
prevalence
MDROs
isolated
individuals
low
diversity
microbiomes
neighborhood
SES.
Our
integrated
population-based
study
considers
how
interplay
several
social
economic
factors
combine
influence
while
providing
framework
for
developing
future
interventions
help
mitigate
gap.
Challenges,
Год журнала:
2023,
Номер
14(1), С. 16 - 16
Опубликована: Март 5, 2023
The
vast
and
growing
challenges
for
human
health
all
life
on
Earth
require
urgent
deep
structural
changes
to
the
way
in
which
we
live.
Broken
relationships
with
nature
are
at
core
of
both
modern
crisis
erosion
planetary
health.
A
declining
connection
has
been
implicated
exploitative
attitudes
that
underpin
degradation
physical
social
environments
almost
aspects
personal
physical,
mental,
spiritual
It
is
increasingly
clear
entwined
biodiversity
loss,
climate
change,
cannot
be
addressed
without
addressing
selfishness,
greed,
apathy,
value
systems
created
these
global
problems.
Calls
a
cultural
transformation
recognize
“inner”
development
important
necessary
meaningful
“outward”
transitions
shared
purpose
wiser,
more
sustainable
societies.
Many
emotional
assets
appear
facilitated
by
nature,
also
strongly
associated
community
cohesion,
prosocial
attitudes,
pro-environmental
actions.
Restoring
may
therefore
provide
critical
common
pathway
promote
wellbeing
individuals
communities
as
well
environmental
responsibility.
In
this
paper,
summarize
reflect
discussions
Nova
Network
respect
nature-based
solutions
pathways
mutualistic
mindset.
These
spanned
biological
psychological
interactions
nature—including
microbes
influence
emotional,
behavioral
We
consider
ways
stronger
“inner
assets”
support
“outward
actions”
Indigenous
Peoples
have
a
rich
and
long-standing
connection
with
the
environments
that
they
descend
from-a
has
informed
deep
multifaceted
understanding
of
relationship
between
human
well-being
environment.
Through
cultural
narratives
practices,
much
this
knowledge
endured
despite
ongoing
effects
colonization
had
on
many
peoples
across
world.
These
based
observation,
experimentation,
practical
application
over
generations,
potential
to
make
compelling
contributions
our
environmental
microbiome
its
health.
Furthermore,
inclusion
perspectives
regarding
opens
pathways
those
who
rarely
engage
field
learnings.
Within
scientific
community,
not
always
been
acknowledged
as
valid
are
often
seen
myth
or
lacking
rigor.
Thus,
paper
aims
explore
an
perspective
unseen
influence
health
by
framing
importance
natural
environment,
leadership,
future
research
directions
can
contribute
domain.
Although
in
article
reflects
experiences,
worldviews,
two
New
Zealand
Māori
authors,
it
is
hoped
concepts
discussed
relate
peoples,
non-Indigenous
advocates,
globally.
Current Biology,
Год журнала:
2023,
Номер
33(10), С. 1939 - 1950.e4
Опубликована: Апрель 27, 2023
The
human
microbiome
seeding
starts
at
birth,
when
pioneer
microbes
are
acquired
mainly
from
the
mother.
Mode
of
delivery,
antibiotic
prophylaxis,
and
feeding
method
have
been
studied
as
modulators
mother-to-infant
transmission,
but
other
key
influencing
factors
like
modern
westernized
lifestyles
with
high
hygienization,
high-calorie
diets,
urban
settings,
compared
non-westernized
not
investigated
yet.
In
this
study,
we
explored
mother-infant
sharing
characterized
uncharacterized
members
via
strain-resolved
metagenomics
in
a
cohort
Ethiopian
mothers
infants,
them
four
cohorts
different
lifestyles.
newborns'
microbiomes
composition
overlapped
during
first
months
life
more
than
later
life,
likely
reflecting
similar
initial
breast-milk-based
diets.
infants
shared
smaller
fraction
their
did
most
populations,
despite
showing
higher
diversity,
species
represented
substantial
those
cohort.
Moreover,
identified
belonging
to
Selenomonadaceae
Prevotellaceae
families
specifically
present
only
cohort,
showed
that
locally
produced
fermented
food,
injera,
can
contribute
diversity
observed
infants'
gut
bacteria
part
through
food
consumption.
Taken
together,
these
findings
highlight
fact
lifestyle
impact
differences
diet,
drug
consumption,
environmental
also
its
effect
on
strain-sharing
patterns.
Environment Systems & Decisions,
Год журнала:
2024,
Номер
44(2), С. 215 - 238
Опубликована: Фев. 24, 2024
Abstract
The
goal
of
engineering
the
microbiome
built
environment
is
to
create
places
and
spaces
that
are
better
for
human
health.
Like
other
emerging
technologies,
may
bring
considerable
benefits
but
there
has
been
a
lack
exploration
on
its
societal
implication
how
engineer
in
an
ethical
way.
To
date,
this
topic
area
also
not
pulled
together
into
singular
study
any
systematic
review
or
analysis.
This
fills
gap
by
providing
first
implications
microbiomes
application
knowledge
environment.
organize
guide
our
analysis,
we
invoked
four
major
principles
(individual
good/non-maleficence,
collective
good/beneficence,
autonomy,
justice)
as
framework
characterizing
categorizing
15
distinct
themes
emerged
from
literature.
We
argue
these
different
can
be
used
explain
predict
social
if
addressed
adequately
help
improve
public
health
field
further
develops
at
global
scales.
