Asia-Pacific Journal of Ophthalmology,
Год журнала:
2025,
Номер
unknown, С. 100196 - 100196
Опубликована: Апрель 1, 2025
This
study
aims
to
examine
the
trends
in
burden
of
visual
impairment
across
Asia
from
1990
2021
and
project
through
2040.
population-based
used
data
latest
Global
Burden
Disease
study.
Prevalence
years
lived
with
disability
(YLDs)
were
main
outcomes.
The
analyzed
by
calculating
average
annual
percentage
change
(AAPC)
using
joinpoint
regression
analysis.
projection
was
performed
Bayesian
age-period-cohort
modeling.
prevalence
increased
2021,
AAPCs
0.77
(95%
confidence
interval
[CI],
0.44
1.11),
while
YLD
rates
decreased
-0.21
CI,
-0.38
-0.03).
Near
vision
loss
contributor
Asia.
Notably,
working-age
population
(20
54
years)
significantly
(AAPC
=
2.11
[95%
1.70
2.53]),
which
accord
YLDs
1.07
0.83
1.32]),
whereas
for
children
adolescents
(<20
elderly
(≥55
it
has
decreased.
According
projection,
predicted
increase
all
Asian
sub-regions,
especially
East
South
been
substantially
increasing
2021.
trend
is
anticipated
persist
soon,
Asia,
underlining
urgent
need
concentrated
attention
robust
policy
support
these
regions.
Adolescent
diabetes
is
one
of
the
major
public
health
problems
worldwide.
This
study
aims
to
estimate
burden
type
1
mellitus
(T1DM)
and
2
(T2DM)
in
adolescents
from
1990
2021,
predict
prevalence
through
2030.
We
extracted
epidemiologic
data
Global
Burden
Disease
(GBD)
on
T1DM
T2DM
among
aged
10–24
years
204
countries
territories
calculated
age-standardized
rate
(ASPR)
DALY
(ASDR)
based
world
standard
population
for
cross-country
comparisons.
Average
annual
percentage
changes
(AAPC)
were
by
linkage
point
regression.
Correlation
analyses
used
identify
relationship
between
sociodemographic
index
(SDI).
The
Bayesian
age-period-cohort
(BAPC)
model
was
2022
In
3.4
million
living
with
T1DM,
an
ASPR
180.96
(95%
CI
180.77–181.15),
14.6
T2DM,
1190.73
(1190.13–1191.34).
As
national
territory
SDI
levels
rise,
increases
(r
=
0.44,
p
<
0.01),
decreases
−
0.18,
0.01).
Compared
males,
females
had
a
greater
(185.49
[185.21–185.76]
vs.
176.66
[176.39–176.92]),
whereas
males
than
did
(1241.45
[1240.58–1242.31]
1138.24
[1137.40–1139.09]).
found
negative
correlation
ASDR
both
0.51,
0.01)
0.62,
adolescents.
For
patients,
32.84%
DALYs
attributed
high
BMI,
which
increased
40.78%
during
period.
By
2030,
3.7
people
are
projected
have
T2DM.
Among
adolescents,
increasing
varies
region,
sex,
SDI.
Therefore,
targeted
interventions
regional
features
needed
prevent
control
adolescent
diabetes.
Moreover,
more
efforts
climate
change
obesity
reduce
burden.
Frontiers in Medicine,
Год журнала:
2025,
Номер
11
Опубликована: Янв. 15, 2025
Chronic
kidney
disease
(CKD)
is
a
significant
global
health
issue,
often
linked
to
diabetes,
hypertension,
and
glomerulonephritis.
However,
aggregated
statistics
can
obscure
heterogeneity
across
subtypes,
age,
gender,
regions.
This
study
aimed
analyze
CKD
trends
from
1990
2021,
focusing
on
socio-demographic
index
(SDI),
regional
variations.
Data
were
extracted
the
Global
Burden
of
Disease
(GBD)
2021
database,
covering
prevalence,
incidence,
mortality,
disability-adjusted
life
years
(DALYs).
These
presented
as
counts
per
100,000
population
age-standardized
rates,
with
uncertainty
intervals
(UIs)
highlight
variability.
Joinpoint
regression
was
used
assess
over
30-year
period.
In
prevalence
359
million,
11.13
million
new
cases,
1.53
deaths,
44.45
DALYs-up
92,
156,
176,
114%
since
1990.
While
slightly
declined,
DALYs
increased
significantly.
burden
varied
by
region
notable
gender
disparities.
The
highlights
dramatic
rise
in
growth
aging,
emphasizing
need
for
targeted
treatment
effective
healthcare
policies.
High
systolic
blood
pressure
(HSBP)
can
cause
adverse
cardiovascular
events
and
is
therefore
associated
with
a
heavy
global
disease
burden.
However,
this
burden
poorly
understood
in
youth
young
adults.
We
aimed
to
explore
population
better
understand
the
evolving
trends
HSBP-related
burden,
which
crucial
for
effectively
controlling
mitigating
harmful
effects.
This
systematic
analysis
used
data
from
2021
Global
Burden
of
Disease
Study,
spanning
1990–2021.
Participants
were
aged
15–39
years
204
countries/territories.
analysed
by
region,
sex,
age,
temporal
trends.
The
primary
outcomes
disability-adjusted
life
(DALYs),
mortality
rates,
estimated
annual
percentage
change.
Globally,
number
deaths
among
adults
has
increased
36.11%
(95%
uncertainty
interval
[95%
UI],
20.96–52.37%),
whereas
DALYs
37.68%
UI,
22.69–53.65%);
however,
DALY
rates
have
remained
relatively
stable.
In
2021,
4.29
3.29–5.28)
263.37
201.40–324.46)
per
100,000
population,
respectively.
overall
was
higher
males
than
females,
increasing
decreasing
Regionally,
significant
improvements
observed
most
high-sociodemographic
index
(SDI)
regions,
including
high-income
Asia
Pacific
(deaths:
change,
−
72.65%;
DALYs:
69.30%)
Western
Europe
72.89%;
67.48%).
contrast,
middle-SDI
regions
had
highest
low-middle-SDI
rates.
Furthermore,
low-SDI
experienced
largest
increase
DALYs.
age;
addition,
proportion
or
due
ischaemic
heart
stroke
reaching
>
75%
those
25
age.
indicates
that
current
preventative
efforts
are
insufficient.
Therefore,
targeted
measures
needed
counter
diseases
reduce
disparities
across
sexes.
BMJ,
Год журнала:
2024,
Номер
unknown, С. q1294 - q1294
Опубликована: Июнь 13, 2024
deteriorating
career
pathways,
restricted
funding,
and
health
service
pressures
are
breaking
it
further.The
complex
challenges
global,
with
regional
national
subtleties.Scan
the
landscape
of
commercialised
life
sciences,
wasteful
research
development,
exploitative
scientific
publishing-taking
in
a
colossal
waste
public
money-and
you
quickly
realise
that
this
one
system
failure
sits
at
centre
Venn
diagram.Academic
medicine
is
not
an
irrelevant
silo.
Journal of Materials Chemistry B,
Год журнала:
2024,
Номер
12(36), С. 8897 - 8901
Опубликована: Янв. 1, 2024
A
Ni
nanoparticle-decorated
TiO
2
nanoribbon
array
on
a
Ti
plate
serves
as
highly
efficient
electrode
for
non-enzymatic
glucose
biosensing
in
alkaline
environments.
EBioMedicine,
Год журнала:
2024,
Номер
107, С. 105270 - 105270
Опубликована: Авг. 12, 2024
Short-term
exposure
to
particulate
matter
air
pollution
has
been
associated
with
the
exacerbations
of
COPD,
but
its
association
COPD
mortality
was
not
fully
elucidated.
We
aimed
assess
between
short-term
and
risk
in
China
using
individual-level
data.
Neuroepidemiology,
Год журнала:
2025,
Номер
unknown, С. 1 - 24
Опубликована: Янв. 21, 2025
Introduction:
In
most
countries
and
territories,
current
data
on
the
burden
of
Alzheimer's
disease
(AD)
other
dementias
are
lacking.
We
aimed
to
assess
trends,
burden,
inequalities
AD
at
global,
regional,
national
level
from
1990
2021.
Methods:
The
during
1990-2021
were
extracted
Global
Burden
Disease
Risk
Factors
Study
2021
(GBD
2021).
Average
annual
percentage
changes
(AAPCs)
age-standardized
prevalence,
mortality,
disability
adjusted
life
years
(DALYs)
estimated
as
an
indicator
evaluate
healthcare
system.
Result:
global
prevalence
increased
672
(95%
uncertainty
interval:
589
764)
per
100,000
population
in
694
(603
794)
2021,
with
AAPCs
0.09%
confidence
0.06%
0.11%).
However,
mortality
did
not
change
(AAPCs:
0.00%
(−0.01%
0.02%))
DALYs
slightly
446
(206
958)
451
(213
950)
0.01%
(0.00%
0.03%).
While
highest
remained
aged
65-69
a
high-middle
socio-demographic
index
(SDI)
such
East
Asia
(e.g.,
China),
found
low-middle
SDI
South
India).
High
fasting
plasma
glucose
ranked
risk
factor
for
1990-2021.
Conclusion:
may
partly
be
attributed
whereas
DALY
ratio
India)
is
significantly
growing.
Controlling
high
needed
reduction
dementias.
Frontiers in Nutrition,
Год журнала:
2025,
Номер
12
Опубликована: Янв. 28, 2025
Non-alcoholic
fatty
liver
disease
(NAFLD)
is
a
significant
health
burden
in
youths
and
young
adults,
the
trend
toward
younger
onset
of
NAFLD
alarming.
Utilizing
data
from
Global
Burden
Disease
(GBD)
2021
study,
this
study
assessed
trends
adults
aged
15–39
1990
to
extracted
on
incidence,
prevalence,
death,
disability-adjusted
life-years
(DALYs)
rates
NAFLD.
We
evaluated
global
temporal
with
estimated
annual
percentage
change
(EAPC)
age-standardized
rate
(ASR).
The
Bayesian
age-period-cohort
(BAPC)
model
was
used
predict
future
2035.
found
that
has
risen
steadily
2021,
projects
increase
2035,
which
places
enormous
pressure
society.
To
alleviate
burden,
implementing
measures
targeting
risk
factors
such
as
glycemic
control
smoking
cessation
necessary.
Research Square (Research Square),
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 28, 2025
Abstract
Background
Brain
and
central
nervous
system
cancer
remains
a
major
healthy
concern
among
the
elder
worldwide.
This
study
is
performed
to
assess
global
burden
of
CNS
adults
aged
≥
65
years
across
204
countries
territories
from
1990
2021
predict
future
trends
in
next
25
years.
Methods
We
analyzed
incidence,
mortality
disability
adjusted
life
(DALYs)
based
on
data
Global
Burden
Disease
Study
2021.
In
addition,
we
obtained
age-standardized
incidence
rate
(ASIR),
age‐standardized
death
(ASDR),
DALYs
during
1990–2021.
Then
assessed
impact
geographical
variations
Socio‐demographic
Index
(SDI)
disease
cancer.
Furthermore,
calculated
EAPC
AAPC
reveal
temporal
Results
Globally,
incident
cases
increased
40344
130100
The
ASIR
rose
3.7
4.3
per
100,000
(EAPC:0.44,
95%
CI:
0.4–0.49).
Low-middle
SDI
regions
showed
largest
increase
(EAPC:1.04,
0.99–1.09),
while
High
had
lowest
(EAPC:0.43,
0.36–0.5).
ASDR
3
3.1
2021,
decreased
119.9
107.9
between
Geographically,
rates
most
territories.
Conclusion
has
risen
sharply
with
divisions
disparities
observed
different
regions.
Specific
medical
interventions
policies
consolidate
early
detection
better
healthcare
service
impoverished
are
essential
for
reducing
