Trends and projections of the burden of visual impairment in Asia: findings from the Global Burden of Disease Study 2021 DOI Creative Commons
Shengsong Xu, Jianqi Chen, Xiao Wang

et al.

Asia-Pacific Journal of Ophthalmology, Journal Year: 2025, Volume and Issue: unknown, P. 100196 - 100196

Published: April 1, 2025

This study aims to examine the trends in burden of visual impairment across Asia from 1990 2021 and project through 2040. population-based used data latest Global Burden Disease study. Prevalence years lived with disability (YLDs) were main outcomes. The analyzed by calculating average annual percentage change (AAPC) using joinpoint regression analysis. projection was performed Bayesian age-period-cohort modeling. prevalence increased 2021, AAPCs 0.77 (95% confidence interval [CI], 0.44 1.11), while YLD rates decreased -0.21 CI, -0.38 -0.03). Near vision loss contributor Asia. Notably, working-age population (20 54 years) significantly (AAPC = 2.11 [95% 1.70 2.53]), which accord YLDs 1.07 0.83 1.32]), whereas for children adolescents (<20 elderly (≥55 it has decreased. According projection, predicted increase all Asian sub-regions, especially East South been substantially increasing 2021. trend is anticipated persist soon, Asia, underlining urgent need concentrated attention robust policy support these regions.

Language: Английский

Global, regional, and national burdens of type 1 and type 2 diabetes mellitus in adolescents from 1990 to 2021, with forecasts to 2030: a systematic analysis of the global burden of disease study 2021 DOI Creative Commons
Xing Chen, Luying Zhang, Wen Chen

et al.

BMC Medicine, Journal Year: 2025, Volume and Issue: 23(1)

Published: Jan. 29, 2025

Adolescent diabetes is one of the major public health problems worldwide. This study aims to estimate burden type 1 mellitus (T1DM) and 2 (T2DM) in adolescents from 1990 2021, predict prevalence through 2030. We extracted epidemiologic data Global Burden Disease (GBD) on T1DM T2DM among aged 10–24 years 204 countries territories calculated age-standardized rate (ASPR) DALY (ASDR) based world standard population for cross-country comparisons. Average annual percentage changes (AAPC) were by linkage point regression. Correlation analyses used identify relationship between sociodemographic index (SDI). The Bayesian age-period-cohort (BAPC) model was 2022 In 3.4 million living with T1DM, an ASPR 180.96 (95% CI 180.77–181.15), 14.6 T2DM, 1190.73 (1190.13–1191.34). As national territory SDI levels rise, increases (r = 0.44, p < 0.01), decreases − 0.18, 0.01). Compared males, females had a greater (185.49 [185.21–185.76] vs. 176.66 [176.39–176.92]), whereas males than did (1241.45 [1240.58–1242.31] 1138.24 [1137.40–1139.09]). found negative correlation ASDR both 0.51, 0.01) 0.62, adolescents. For patients, 32.84% DALYs attributed high BMI, which increased 40.78% during period. By 2030, 3.7 people are projected have T2DM. Among adolescents, increasing varies region, sex, SDI. Therefore, targeted interventions regional features needed prevent control adolescent diabetes. Moreover, more efforts climate change obesity reduce burden.

Language: Английский

Citations

3
Global, regional, and national burden inequality of chronic kidney disease, 1990–2021: a systematic analysis for the global burden of disease study 2021 DOI Creative Commons
Jeff J. Guo, Zhen Liu, Pengjun Wang

et al.

Frontiers in Medicine, Journal Year: 2025, Volume and Issue: 11

Published: Jan. 15, 2025

Chronic kidney disease (CKD) is a significant global health issue, often linked to diabetes, hypertension, and glomerulonephritis. However, aggregated statistics can obscure heterogeneity across subtypes, age, gender, regions. This study aimed analyze CKD trends from 1990 2021, focusing on socio-demographic index (SDI), regional variations. Data were extracted the Global Burden of Disease (GBD) 2021 database, covering prevalence, incidence, mortality, disability-adjusted life years (DALYs). These presented as counts per 100,000 population age-standardized rates, with uncertainty intervals (UIs) highlight variability. Joinpoint regression was used assess over 30-year period. In prevalence 359 million, 11.13 million new cases, 1.53 deaths, 44.45 DALYs-up 92, 156, 176, 114% since 1990. While slightly declined, DALYs increased significantly. burden varied by region notable gender disparities. The highlights dramatic rise in growth aging, emphasizing need for targeted treatment effective healthcare policies.

Language: Английский

Citations

2
Global, regional, and national disease burden attributable to high systolic blood pressure in youth and young adults: 2021 Global Burden of Disease Study analysis DOI Creative Commons
Chuan He, Saien Lu, Haijie Yu

et al.

BMC Medicine, Journal Year: 2025, Volume and Issue: 23(1)

Published: Feb. 6, 2025

High systolic blood pressure (HSBP) can cause adverse cardiovascular events and is therefore associated with a heavy global disease burden. However, this burden poorly understood in youth young adults. We aimed to explore population better understand the evolving trends HSBP-related burden, which crucial for effectively controlling mitigating harmful effects. This systematic analysis used data from 2021 Global Burden of Disease Study, spanning 1990–2021. Participants were aged 15–39 years 204 countries/territories. analysed by region, sex, age, temporal trends. The primary outcomes disability-adjusted life (DALYs), mortality rates, estimated annual percentage change. Globally, number deaths among adults has increased 36.11% (95% uncertainty interval [95% UI], 20.96–52.37%), whereas DALYs 37.68% UI, 22.69–53.65%); however, DALY rates have remained relatively stable. In 2021, 4.29 3.29–5.28) 263.37 201.40–324.46) per 100,000 population, respectively. overall was higher males than females, increasing decreasing Regionally, significant improvements observed most high-sociodemographic index (SDI) regions, including high-income Asia Pacific (deaths: change, − 72.65%; DALYs: 69.30%) Western Europe 72.89%; 67.48%). contrast, middle-SDI regions had highest low-middle-SDI rates. Furthermore, low-SDI experienced largest increase DALYs. age; addition, proportion or due ischaemic heart stroke reaching > 75% those 25 age. indicates that current preventative efforts are insufficient. Therefore, targeted measures needed counter diseases reduce disparities across sexes.

Language: Английский

Citations

2
The BMJ Commission on the Future of Academic Medicine DOI Open Access
Kamran Abbasi

BMJ, Journal Year: 2024, Volume and Issue: unknown, P. q1294 - q1294

Published: June 13, 2024

deteriorating career pathways, restricted funding, and health service pressures are breaking it further.The complex challenges global, with regional national subtleties.Scan the landscape of commercialised life sciences, wasteful research development, exploitative scientific publishing-taking in a colossal waste public money-and you quickly realise that this one system failure sits at centre Venn diagram.Academic medicine is not an irrelevant silo.

Language: Английский

Citations

7
Ni@TiO2 nanoribbon array electrode for high-efficiency non-enzymatic glucose biosensing DOI

Peilin Wu,

Jianying Yang,

Yunze Tai

et al.

Journal of Materials Chemistry B, Journal Year: 2024, Volume and Issue: 12(36), P. 8897 - 8901

Published: Jan. 1, 2024

A Ni nanoparticle-decorated TiO 2 nanoribbon array on a Ti plate serves as highly efficient electrode for non-enzymatic glucose biosensing in alkaline environments.

Language: Английский

Citations

5
Ambient particulate matter and chronic obstructive pulmonary disease mortality: a nationwide, individual-level, case-crossover study in China DOI Creative Commons
Shuo Jiang,

Xunliang Tong,

Kexin Yu

et al.

EBioMedicine, Journal Year: 2024, Volume and Issue: 107, P. 105270 - 105270

Published: Aug. 12, 2024

Short-term exposure to particulate matter air pollution has been associated with the exacerbations of COPD, but its association COPD mortality was not fully elucidated. We aimed assess between short-term and risk in China using individual-level data.

Language: Английский

Citations

4
Global burden of Alzheimer's disease and other dementias during 1990-2021: a Global Burden of Disease and Risk Factors Study 2021-based study DOI Creative Commons
Renxi Wang

Neuroepidemiology, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 24

Published: Jan. 21, 2025

Introduction: In most countries and territories, current data on the burden of Alzheimer's disease (AD) other dementias are lacking. We aimed to assess trends, burden, inequalities AD at global, regional, national level from 1990 2021. Methods: The during 1990-2021 were extracted Global Burden Disease Risk Factors Study 2021 (GBD 2021). Average annual percentage changes (AAPCs) age-standardized prevalence, mortality, disability adjusted life years (DALYs) estimated as an indicator evaluate healthcare system. Result: global prevalence increased 672 (95% uncertainty interval: 589 764) per 100,000 population in 694 (603 794) 2021, with AAPCs 0.09% confidence 0.06% 0.11%). However, mortality did not change (AAPCs: 0.00% (−0.01% 0.02%)) DALYs slightly 446 (206 958) 451 (213 950) 0.01% (0.00% 0.03%). While highest remained aged 65-69 a high-middle socio-demographic index (SDI) such East Asia (e.g., China), found low-middle SDI South India). High fasting plasma glucose ranked risk factor for 1990-2021. Conclusion: may partly be attributed whereas DALY ratio India) is significantly growing. Controlling high needed reduction dementias.

Language: Английский

Citations

0
The Value of Medical Nutrition Therapy and Diabetes Self-Management Education and Support in Diabetes Care and Education: A Call to Action to Increase Referrals and Recognize Insurance Coverage Variation DOI

Amy Hess-Fischl

Current Diabetes Reports, Journal Year: 2025, Volume and Issue: 25(1)

Published: Jan. 23, 2025

Language: Английский

Citations

0
Global, regional, and national burden of NAFLD in youths and young adults aged 15–39 years, 1990–2021, its attributable risk factors, and projections to 2035: a systematic analysis of the Global Burden of Disease Study 2021 DOI Creative Commons
Jiong Wang,

Jiqing Du,

Minxiu Wang

et al.

Frontiers in Nutrition, Journal Year: 2025, Volume and Issue: 12

Published: Jan. 28, 2025

Non-alcoholic fatty liver disease (NAFLD) is a significant health burden in youths and young adults, the trend toward younger onset of NAFLD alarming. Utilizing data from Global Burden Disease (GBD) 2021 study, this study assessed trends adults aged 15–39 1990 to extracted on incidence, prevalence, death, disability-adjusted life-years (DALYs) rates NAFLD. We evaluated global temporal with estimated annual percentage change (EAPC) age-standardized rate (ASR). The Bayesian age-period-cohort (BAPC) model was used predict future 2035. found that has risen steadily 2021, projects increase 2035, which places enormous pressure society. To alleviate burden, implementing measures targeting risk factors such as glycemic control smoking cessation necessary.

Language: Английский

Citations

0
Global burden of brain and other central nervous system cancer in older adults aged over 65: a population-based study DOI Creative Commons
Shujun Xu, Guoming Hu

Research Square (Research Square), Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 28, 2025

Abstract Background Brain and central nervous system cancer remains a major healthy concern among the elder worldwide. This study is performed to assess global burden of CNS adults aged ≥ 65 years across 204 countries territories from 1990 2021 predict future trends in next 25 years. Methods We analyzed incidence, mortality disability adjusted life (DALYs) based on data Global Burden Disease Study 2021. In addition, we obtained age-standardized incidence rate (ASIR), age‐standardized death (ASDR), DALYs during 1990–2021. Then assessed impact geographical variations Socio‐demographic Index (SDI) disease cancer. Furthermore, calculated EAPC AAPC reveal temporal Results Globally, incident cases increased 40344 130100 The ASIR rose 3.7 4.3 per 100,000 (EAPC:0.44, 95% CI: 0.4–0.49). Low-middle SDI regions showed largest increase (EAPC:1.04, 0.99–1.09), while High had lowest (EAPC:0.43, 0.36–0.5). ASDR 3 3.1 2021, decreased 119.9 107.9 between Geographically, rates most territories. Conclusion has risen sharply with divisions disparities observed different regions. Specific medical interventions policies consolidate early detection better healthcare service impoverished are essential for reducing

Language: Английский

Citations

0