The Journal of Internal Korean Medicine,
Год журнала:
2024,
Номер
45(6), С. 1402 - 1408
Опубликована: Дек. 30, 2024
Objective:
This
case
report
aims
to
illustrate
the
effect
of
three
different
Korean
medicines
on
hyperhidrosis
scalp
following
a
COVID-19
infection.Methods:
The
patient,
who
developed
post-COVID-19,
was
treated
with
medicine.
Symptom
improvement
evaluated
using
Hyperhidrosis
Disease
Severity
Scale
(HDSS)
and
Quality
Life
Index
(HidroQoL),
which
includes
patient
feedback
daily
life
activities
psychosocial
factors.Results:
HDSS
HidroQoL
scores
both
decreased,
indicating
symptom
after
herbal
medicine
treatment.Conclusion:
suggests
that
could
provide
symptomatic
relief
for
associated
long
COVID-19.
To
achieve
more
definitive
validation,
additional
studies
objective
measures
are
necessary.
Journal of Advances in Medicine and Medical Research,
Год журнала:
2024,
Номер
36(6), С. 160 - 176
Опубликована: Июнь 2, 2024
The
association
between
COVID-19
and
heart
failure
(HF)
presents
multifaceted
challenges
implications
for
clinical
management.
This
comprehensive
review
explores
the
epidemiological,
clinical,
mechanistic
associations
HF,
emphasizing
bidirectional
impact
of
these
conditions
on
patient
outcomes.
can
precipitate
or
exacerbate
HF
through
myocardial
injury,
inflammation,
thrombosis,
immune
dysregulation,
while
pre-existing
increases
severity
complications
COVID-19.
Diagnostic
arise
from
overlapping
symptoms
need
to
differentiate
COVID-19-related
lung
pathology
manifestations.
Understanding
underlying
pathophysiological
mechanisms,
including
ACE2
cytokine
release
syndrome,
hypercoagulability,
is
crucial
optimizing
management
strategies.
Early
identification,
multidisciplinary
collaboration,
personalized
treatment,
education
are
essential
managing
HF.
Insights
this
inform
practice,
highlighting
importance
tailored
interventions
ongoing
research
mitigate
complex
interactions
outcomes
public
health
initiatives.
Heliyon,
Год журнала:
2024,
Номер
10(22), С. e40453 - e40453
Опубликована: Ноя. 1, 2024
Relatively
few
studies
have
explored
the
impact
of
home
telerehabilitation-based
(HTB)
programs
on
patients
with
post-COVID-19
syndrome.
Thus,
this
study
aimed
to
investigate
effect
HTB
cardiopulmonary
function,
body
composition,
muscle
strength,
and
quality
life
(QoL)
Journal of Sulfur Chemistry,
Год журнала:
2024,
Номер
46(1), С. 35 - 54
Опубликована: Ноя. 14, 2024
Unlike
most
attempts
to
find
compounds
with
activity
against
SARS-CoV-2
aimed
at
reusing
approved
drugs,
our
goal
was
antiviral
among
the
1,2-dithioloquinoline
derivatives
we
synthesized.
These
exhibit
pleiotropic
effects,
having
a
novel
structure
compared
known
pharmaceuticals.
In
this
work,
diversified
of
by
introducing
various
substituents
(chlorine
atom,
ether,
amide,
sulfonamide
groups,
pharmacophore
heterocycles)
into
different
positions
tricyclic
framework.
Using
docking
further
quantum
chemical
post-processing
calculations
created
virtual
library
404
structures,
more
than
ten
aryl(4,4-dimethyl-4,5-dihydro-1H-[1,2]dithiolo[3,4-c]quinoline-1-ylidene)amine
series
were
discovered,
synthesized
and
experimentally
studied.
The
bioactive
screening
newly
revealed
that
six
them
demonstrate
suppression
replication
in
Vero
E6
cell
culture
micromolar
range
EC50
values
(from
0.27
98.48
μM).
best
compound,
which
fragments
dithioloquinoline
streptocide
are
combined,
demonstrated
highest
ability
protect
cells
from
=
μM,
as
well
low
cytotoxicity
selectivity
index
SI
>
370,
exceeding
all
reference
used
study
(remdesivir,
GC376,
ML188).
The Journal of Internal Korean Medicine,
Год журнала:
2024,
Номер
45(6), С. 1402 - 1408
Опубликована: Дек. 30, 2024
Objective:
This
case
report
aims
to
illustrate
the
effect
of
three
different
Korean
medicines
on
hyperhidrosis
scalp
following
a
COVID-19
infection.Methods:
The
patient,
who
developed
post-COVID-19,
was
treated
with
medicine.
Symptom
improvement
evaluated
using
Hyperhidrosis
Disease
Severity
Scale
(HDSS)
and
Quality
Life
Index
(HidroQoL),
which
includes
patient
feedback
daily
life
activities
psychosocial
factors.Results:
HDSS
HidroQoL
scores
both
decreased,
indicating
symptom
after
herbal
medicine
treatment.Conclusion:
suggests
that
could
provide
symptomatic
relief
for
associated
long
COVID-19.
To
achieve
more
definitive
validation,
additional
studies
objective
measures
are
necessary.
