A study protocol for exploring and implementing a surgical pharmaceutical service model in drug treatment management for patients with osteoporosis fracture in China DOI Creative Commons

Jieluan Lu,

Yixin Luo,

Cai De

и другие.

Frontiers in Medicine, Год журнала: 2025, Номер 12

Опубликована: Март 12, 2025

Background Osteoporotic fractures are serious consequences of osteoporosis, which is a condition that can be prevented through effective therapeutic strategies, including the use anti-osteoporotic medications. However, significant treatment gap exists in elderly patients with osteoporotic fractures. A multicenter study conducted China reported only 20% hip received appropriate pharmacotherapy post-fracture. This lack resulted an increased risk refracture associated osteoporosis. Pharmacist-led interventions have proven essential medication management for osteoporosis and related fractures, potentially bridging gap. Accordingly, protocol was developed to assess impact pharmacist-led on increasing continuation rates drugs reducing fracture, compared no (grant number: YCTJ-2023-15). Methods analysis single-center, prospective, randomized controlled trial. The targeted participants this were aged above 50 years who had been diagnosed China. Eligible into intervention control groups 1:1 ratio using dynamic stratified block randomization method. group standard care, care combined care. comprehensive interventions, pharmaceutical ward rounds reconciliation, evaluation, recommendations physicians, patient education, counseling. 2-year follow-up evaluate outcomes between telephone interviews, clinics, e-hospital pharmacy practice. primary outcome ongoing drugs. defined as remain medications at each visit total number enrolled participants. Secondary include initiation rates, adherence, re-fractures, increase fall risk, frequency bone mineral density (BMD) assessments, incidence inappropriate use, adverse drug reactions (ADRs), satisfaction fracture treatment. Refracture evaluated follow-up, while BMD measured baseline, 1 year, 2 dual-energy X-ray absorptiometry (DXA). ADRs monitored self-reports reconciliation. Patient assessed Treatment Satisfaction Questionnaire Medication version II (TSQM-II). Ethical approval obtained from Committee Ethics First Affiliated Hospital Shantou University Medical College (approval B-2023-194). statistical performed Statistics Package Social Science (SPSS), 23.0. Discussion We hypothesize analyzing pharmacists-led provide valuable insights how pharmacists improve aims address existing knowledge regarding effectiveness improving

Язык: Английский

Antiresorptive injections in older adult patients with prior osteoporotic fractures: a real-world observational study DOI
Chun‐Feng Huang, Hsing‐Juh Lin, Jason C. Hsu

и другие.

Archives of Osteoporosis, Год журнала: 2025, Номер 20(1)

Опубликована: Фев. 16, 2025

Язык: Английский

Процитировано

0
A study protocol for exploring and implementing a surgical pharmaceutical service model in drug treatment management for patients with osteoporosis fracture in China DOI Creative Commons

Jieluan Lu,

Yixin Luo,

Cai De

и другие.

Frontiers in Medicine, Год журнала: 2025, Номер 12

Опубликована: Март 12, 2025

Background Osteoporotic fractures are serious consequences of osteoporosis, which is a condition that can be prevented through effective therapeutic strategies, including the use anti-osteoporotic medications. However, significant treatment gap exists in elderly patients with osteoporotic fractures. A multicenter study conducted China reported only 20% hip received appropriate pharmacotherapy post-fracture. This lack resulted an increased risk refracture associated osteoporosis. Pharmacist-led interventions have proven essential medication management for osteoporosis and related fractures, potentially bridging gap. Accordingly, protocol was developed to assess impact pharmacist-led on increasing continuation rates drugs reducing fracture, compared no (grant number: YCTJ-2023-15). Methods analysis single-center, prospective, randomized controlled trial. The targeted participants this were aged above 50 years who had been diagnosed China. Eligible into intervention control groups 1:1 ratio using dynamic stratified block randomization method. group standard care, care combined care. comprehensive interventions, pharmaceutical ward rounds reconciliation, evaluation, recommendations physicians, patient education, counseling. 2-year follow-up evaluate outcomes between telephone interviews, clinics, e-hospital pharmacy practice. primary outcome ongoing drugs. defined as remain medications at each visit total number enrolled participants. Secondary include initiation rates, adherence, re-fractures, increase fall risk, frequency bone mineral density (BMD) assessments, incidence inappropriate use, adverse drug reactions (ADRs), satisfaction fracture treatment. Refracture evaluated follow-up, while BMD measured baseline, 1 year, 2 dual-energy X-ray absorptiometry (DXA). ADRs monitored self-reports reconciliation. Patient assessed Treatment Satisfaction Questionnaire Medication version II (TSQM-II). Ethical approval obtained from Committee Ethics First Affiliated Hospital Shantou University Medical College (approval B-2023-194). statistical performed Statistics Package Social Science (SPSS), 23.0. Discussion We hypothesize analyzing pharmacists-led provide valuable insights how pharmacists improve aims address existing knowledge regarding effectiveness improving

Язык: Английский

Процитировано

0