A study protocol for exploring and implementing a surgical pharmaceutical service model in drug treatment management for patients with osteoporosis fracture in China DOI Creative Commons

Jieluan Lu,

Yixin Luo,

Cai De

et al.

Frontiers in Medicine, Journal Year: 2025, Volume and Issue: 12

Published: March 12, 2025

Background Osteoporotic fractures are serious consequences of osteoporosis, which is a condition that can be prevented through effective therapeutic strategies, including the use anti-osteoporotic medications. However, significant treatment gap exists in elderly patients with osteoporotic fractures. A multicenter study conducted China reported only 20% hip received appropriate pharmacotherapy post-fracture. This lack resulted an increased risk refracture associated osteoporosis. Pharmacist-led interventions have proven essential medication management for osteoporosis and related fractures, potentially bridging gap. Accordingly, protocol was developed to assess impact pharmacist-led on increasing continuation rates drugs reducing fracture, compared no (grant number: YCTJ-2023-15). Methods analysis single-center, prospective, randomized controlled trial. The targeted participants this were aged above 50 years who had been diagnosed China. Eligible into intervention control groups 1:1 ratio using dynamic stratified block randomization method. group standard care, care combined care. comprehensive interventions, pharmaceutical ward rounds reconciliation, evaluation, recommendations physicians, patient education, counseling. 2-year follow-up evaluate outcomes between telephone interviews, clinics, e-hospital pharmacy practice. primary outcome ongoing drugs. defined as remain medications at each visit total number enrolled participants. Secondary include initiation rates, adherence, re-fractures, increase fall risk, frequency bone mineral density (BMD) assessments, incidence inappropriate use, adverse drug reactions (ADRs), satisfaction fracture treatment. Refracture evaluated follow-up, while BMD measured baseline, 1 year, 2 dual-energy X-ray absorptiometry (DXA). ADRs monitored self-reports reconciliation. Patient assessed Treatment Satisfaction Questionnaire Medication version II (TSQM-II). Ethical approval obtained from Committee Ethics First Affiliated Hospital Shantou University Medical College (approval B-2023-194). statistical performed Statistics Package Social Science (SPSS), 23.0. Discussion We hypothesize analyzing pharmacists-led provide valuable insights how pharmacists improve aims address existing knowledge regarding effectiveness improving

Language: Английский

Antiresorptive injections in older adult patients with prior osteoporotic fractures: a real-world observational study DOI
Chun‐Feng Huang, Hsing‐Juh Lin, Jason C. Hsu

et al.

Archives of Osteoporosis, Journal Year: 2025, Volume and Issue: 20(1)

Published: Feb. 16, 2025

Language: Английский

Citations

0
A study protocol for exploring and implementing a surgical pharmaceutical service model in drug treatment management for patients with osteoporosis fracture in China DOI Creative Commons

Jieluan Lu,

Yixin Luo,

Cai De

et al.

Frontiers in Medicine, Journal Year: 2025, Volume and Issue: 12

Published: March 12, 2025

Background Osteoporotic fractures are serious consequences of osteoporosis, which is a condition that can be prevented through effective therapeutic strategies, including the use anti-osteoporotic medications. However, significant treatment gap exists in elderly patients with osteoporotic fractures. A multicenter study conducted China reported only 20% hip received appropriate pharmacotherapy post-fracture. This lack resulted an increased risk refracture associated osteoporosis. Pharmacist-led interventions have proven essential medication management for osteoporosis and related fractures, potentially bridging gap. Accordingly, protocol was developed to assess impact pharmacist-led on increasing continuation rates drugs reducing fracture, compared no (grant number: YCTJ-2023-15). Methods analysis single-center, prospective, randomized controlled trial. The targeted participants this were aged above 50 years who had been diagnosed China. Eligible into intervention control groups 1:1 ratio using dynamic stratified block randomization method. group standard care, care combined care. comprehensive interventions, pharmaceutical ward rounds reconciliation, evaluation, recommendations physicians, patient education, counseling. 2-year follow-up evaluate outcomes between telephone interviews, clinics, e-hospital pharmacy practice. primary outcome ongoing drugs. defined as remain medications at each visit total number enrolled participants. Secondary include initiation rates, adherence, re-fractures, increase fall risk, frequency bone mineral density (BMD) assessments, incidence inappropriate use, adverse drug reactions (ADRs), satisfaction fracture treatment. Refracture evaluated follow-up, while BMD measured baseline, 1 year, 2 dual-energy X-ray absorptiometry (DXA). ADRs monitored self-reports reconciliation. Patient assessed Treatment Satisfaction Questionnaire Medication version II (TSQM-II). Ethical approval obtained from Committee Ethics First Affiliated Hospital Shantou University Medical College (approval B-2023-194). statistical performed Statistics Package Social Science (SPSS), 23.0. Discussion We hypothesize analyzing pharmacists-led provide valuable insights how pharmacists improve aims address existing knowledge regarding effectiveness improving

Language: Английский

Citations

0