Nutritional Composition and Bioactive Compounds in Tomatoes and Their Impact on Human Health and Disease: A Review

Foods, Год журнала: 2020, Номер 10(1), С. 45 - 45

Опубликована: Дек. 26, 2020

Tomatoes are consumed worldwide as fresh vegetables because of their high contents essential nutrients and antioxidant-rich phytochemicals. contain minerals, vitamins, proteins, amino acids (leucine, threonine, valine, histidine, lysine, arginine), monounsaturated fatty (linoleic linolenic acids), carotenoids (lycopene β-carotenoids) phytosterols (β-sitosterol, campesterol stigmasterol). Lycopene is the main dietary carotenoid in tomato tomato-based food products lycopene consumption by humans has been reported to protect against cancer, cardiovascular diseases, cognitive function osteoporosis. Among phenolic compounds present tomato, quercetin, kaempferol, naringenin, caffeic acid lutein most common. Many these have antioxidant activities effective protecting human body various oxidative stress-related diseases. Dietary tomatoes increase body's level antioxidants, trapping reactive oxygen species reducing damage important biomolecules such membrane lipids, enzymatic proteins DNA, thereby ameliorating stress. We reviewed nutritional phytochemical compositions tomatoes. In addition, impacts constituents on health, particularly some degenerative also discussed.

Язык: Английский

---

Oxidative Stress in Ageing and Chronic Degenerative Pathologies: Molecular Mechanisms Involved in Counteracting Oxidative Stress and Chronic Inflammation

International Journal of Molecular Sciences, Год журнала: 2022, Номер 23(13), С. 7273 - 7273

Опубликована: Июнь 30, 2022

Ageing and chronic degenerative pathologies demonstrate the shared characteristics of high bioavailability reactive oxygen species (ROS) oxidative stress, chronic/persistent inflammation, glycation, mitochondrial abnormalities. Excessive ROS production results in nucleic acid protein destruction, thereby altering cellular structure functional outcome. To stabilise increased modulate human body produces antioxidants, “free radical scavengers”, that inhibit or delay cell damage. Reinforcing antioxidant defence system and/or counteracting deleterious repercussions immoderate nitrogen (RONS) is critical may curb progression ageing syndromes. Various therapeutic methods for stress reduction have been developed. However, scientific investigations are required to assess their efficacy. In this review, we summarise interconnected mechanism inflammation contributes pathologies, including neurodegenerative diseases, such as Alzheimer’s disease (AD) Parkinson’s (PD), cardiovascular diseases CVD, diabetes mellitus (DM), kidney (CKD). We also highlight potential counteractive measures combat diseases.

Язык: Английский

---

Synthesis, applications, toxicity and toxicity mechanisms of silver nanoparticles: A review

Ecotoxicology and Environmental Safety, Год журнала: 2023, Номер 253, С. 114636 - 114636

Опубликована: Фев. 15, 2023

Silver nanoparticles (AgNPs) have become one of the most popular objects study for past few decades. The ability to design AgNPs through different synthetic methods according application area and desired features is their advantage in many applications. Green synthesis silver has potential methods. Because strong antibacterial activity, been used a wide range applications, such as food packaging medical products devices. With increasing AgNPs, it becoming necessary better understanding toxicity mechanism toxicity. In review, we first describe AgNPs. field then briefly described. mechanisms are discussed.

Язык: Английский

---

Overview of the Mechanisms of Oxidative Stress: Impact in Inflammation of the Airway Diseases

Antioxidants, Год журнала: 2022, Номер 11(11), С. 2237 - 2237

Опубликована: Ноя. 13, 2022

Inflammation of the human lung is mediated in response to different stimuli (e.g., physical, radioactive, infective, pro-allergenic or toxic) such as cigarette smoke and environmental pollutants. They often promote an increase inflammatory activities airways that manifest themselves chronic diseases allergic airway diseases, asthma, bronchitis/chronic obstructive pulmonary disease (COPD) even cancer). Increased levels oxidative stress (OS) reduce antioxidant defenses, affect autophagy/mitophagy processes, regulatory mechanisms cell survival, promoting inflammation lung. In fact, OS potentiate lung, favoring progression diseases. increases production reactive oxygen species (ROS), including superoxide anions (O2-), hydroxyl radicals (OH) hydrogen peroxide (H2O2), by transformation through enzymatic non-enzymatic reactions. this manner, reduces endogenous defenses both nucleated non-nucleated cells. The ROS can derive from exogenous insults (cigarette pollution) sources injury and/or activated structural review, we describe most relevant knowledge concerning functional interrelation between

Язык: Английский

---

Short-chain per- and polyfluoralkyl substances (PFAS) effects on oxidative stress biomarkers in human liver, kidney, muscle, and microglia cell lines

Environmental Research, Год журнала: 2023, Номер 223, С. 115424 - 115424

Опубликована: Фев. 3, 2023

Язык: Английский

---

Bioactive peptides derived from fermented foods: Preparation and biological activities

Journal of Functional Foods, Год журнала: 2023, Номер 101, С. 105422 - 105422

Опубликована: Фев. 1, 2023

Bioactive peptides (BAPs) with potential health benefits are gaining popularity as people become more health-conscious. Fermented foods produced through the vigorous metabolic activities of numerous microorganisms, which convert macromolecules in food matrix into bioactive components, including BAPs. Access to endogenous BAPs fermented reduces costs while simplifying isolation steps and provides a high-quality direct source foods-derived have been shown antihypertensive, antioxidant, antibacterial activities; however, there is lack information on production foods, large number resources not effectively explored. Therefore, this review introduces current research status, preparation methods, biological functions, digestive stability followed by discussion shortcomings future directions provide foundation for applications pharmaceutical fields.

Язык: Английский

---

Microalgal bioactive metabolites as promising implements in nutraceuticals and pharmaceuticals: inspiring therapy for health benefits

Phytochemistry Reviews, Год журнала: 2023, Номер 22(4), С. 903 - 933

Опубликована: Янв. 14, 2023

Язык: Английский

---

Optimization of ultrasound-aided extraction of bioactive ingredients from Vitis vinifera seeds using RSM and ANFIS modeling with machine learning algorithm

Scientific Reports, Год журнала: 2024, Номер 14(1)

Опубликована: Янв. 12, 2024

Plant materials are a rich source of polyphenolic compounds with interesting health-beneficial effects. The present study aimed to determine the optimized condition for maximum extraction polyphenols from grape seeds through RSM (response surface methodology), ANFIS (adaptive neuro-fuzzy inference system), and machine learning (ML) algorithm models. Effect five independent variables their ranges, particle size (X

Язык: Английский

---

Sexual Dimorphism in Migraine. Focus on Mitochondria

Current Pain and Headache Reports, Год журнала: 2025, Номер 29(1)

Опубликована: Янв. 6, 2025

Язык: Английский

---

The medicinal and aromatic plants as ingredients in functional beverage production

Journal of Functional Foods, Год журнала: 2022, Номер 96, С. 105210 - 105210

Опубликована: Авг. 9, 2022

The functional beverages (FBs) are an important segment of food products due to health benefits they provide and their appealing sensory characteristics, suitability affordability. FBs market offers many opportunities for new product development (nutraceuticals, colorants, plant-based medicines products) with desirable effective composition nutrients bioactive molecules (BAMs) aimed deliver improve human well-being. Recently, the use medicinal aromatic plants (MAPs) in production has become increasingly popular specific content (amino fatty acids) BAMs (volatile non-volatile) attributed biological effects benefits. stored leaves, flowers, fruits, seeds, barks roots, mostly include phenolics (phenolic acids, flavonoids, tanins, anthocyanins, lignans stilbenes), essential oils (EOs), terpenoids, alkaloids, phytosterols saponins. features MAPs mainly related volatile compounds EOs, but presence non-volatile compounds, such as phenolics, also contributes properties. Phytochemical profiling plant species containing complex mixtures BAMs, provides numerous categories FBs, opens challenges isolation using conventional advanced extraction techniques, well determination potential effects. This review summarizes most common from selected effects, techniques suitable extracts quality prediction trends, several directions towards future research on strategies.

Язык: Английский

---