Archives of Toxicology, Год журнала: 2025, Номер unknown
Опубликована: Фев. 17, 2025
Язык: Английский
International Journal of Molecular Sciences, Год журнала: 2023, Номер 24(20), С. 15397 - 15397
Опубликована: Окт. 20, 2023
In recent years, interest in nanotechnology has increased exponentially due to enhanced progress and technological innovation. tissue engineering, the development of metallic nanoparticles been amplified, especially their antibacterial properties. Another important characteristic metal NPs is that they enable high control over features developed scaffolds (optimizing mechanical strength offering controlled release bioactive agents). Currently, main concern related method synthesis oxide environmental impact. The physical chemical uses toxic agents could generate hazards or exert carcinogenicity/environmental toxicity. Therefore, a greener, cleaner, more reliable approach needed. Green synthetic come as solution counter aforementioned limitations. Nowadays, green preferred because it leads prevention/minimization waste, reduction derivatives/pollution, use non-toxic (safer) solvents. This not only biomass sources reducing for salts. biomolecules also cover synthesized act situ capping agents. Further, involvement formation process reduces toxicity, prevents nanoparticle agglomeration, improves antimicrobial activity nanomaterial, leading possible synergistic effect. study aims provide comprehensive review nanoparticles, from routes, selected solvents, parameters latest application biomedical field.
Язык: Английский
Процитировано
84
Biocatalysis and Agricultural Biotechnology, Год журнала: 2024, Номер 57, С. 103121 - 103121
Опубликована: Март 19, 2024
Язык: Английский
Процитировано
56
The Science of The Total Environment, Год журнала: 2023, Номер 908, С. 168318 - 168318
Опубликована: Ноя. 11, 2023
Язык: Английский
Процитировано
48
Discover Nano, Год журнала: 2023, Номер 18(1)
Опубликована: Дек. 19, 2023
The nanosystems for delivering drugs which have evolved with time, are being designed greater drug efficiency and lesser side-effects, also complemented by the advancement of numerous innovative materials. In comparison to organic nanoparticles, inorganic nanoparticles stable, a wide range physicochemical, mechanical, magnetic, optical characteristics, capability get modified using some ligands enrich their attraction towards molecules at target site, makes them appealing bio-imaging delivery applications. One strong benefits nanoparticles-drug conjugate is possibility affected cells locally, thus reducing side-effects like cytotoxicity, facilitating higher efficacy therapeutic drug. This review features direct indirect effects such gold, silver, graphene-based, hydroxyapatite, iron oxide, ZnO, CeO2 in developing effective carrier systems. article has remarked peculiarities these nanoparticle-based systems pulmonary, ocular, wound healing, antibacterial deliveries as well across Blood-Brain-Barrier (BBB) acting agents cancer theranostics. Additionally, sheds light on plausible modifications that can be carried out from researcher's perspective, could open new pathway.
Язык: Английский
Процитировано
44
JCIS Open, Год журнала: 2024, Номер 16, С. 100125 - 100125
Опубликована: Окт. 11, 2024
Язык: Английский
Процитировано
39
Nanomaterials, Год журнала: 2024, Номер 14(18), С. 1527 - 1527
Опубликована: Сен. 20, 2024
Recently, silver nanoparticles (NPs) have attracted significant attention for being highly desirable nanomaterials in scientific studies as a result of their extraordinary characteristics. They are widely known effective antibacterial agents that capable targeting wide range pathogens. Their distinct optical characteristics, such localized surface plasmon resonance, enlarge utilization, particularly the fields biosensing and imaging. Also, capacity to control charge modify them using biocompatible substances offers improved durability specific interactions with biological systems. Due exceptional stability minimal chemical reactivity, NPs suitable diverse array applications. These produced through chemical, biological, physical processes, each which has advantages disadvantages. Chemical techniques often encounter issues complicated purification, reactive substances, excessive energy usage. However, eco-friendly approaches exist, even though they require longer processing times. A key factor affecting stability, size distribution, purity is synthesis process selected. This review focuses on how essential it choose appropriate method order optimize characteristics use NPs.
Язык: Английский
Процитировано
30
Heliyon, Год журнала: 2024, Номер 10(11), С. e29766 - e29766
Опубликована: Май 1, 2024
Nanoparticles have recently become considered as a crucial player in contemporary medicine, with therapeutic uses ranging from contrast agents imaging to carriers for the transport of drugs and genes into specific target. ability more precise molecular interactions human body order target cells tissues minimal adverse effects maximal outcomes. With least number side greatest possible benefit, nanoparticles can particular through body. The majority global public health problems are now treated green synthesized silver (AgNPs), which substantially affect fundamental structure DNA proteins thus display their antimicrobial action. AgNPs inhibit proliferation tumor induce oxidative stress. By inhibiting vascular endothelial growth factor (HIF)-1, pro-inflammatory mediators generated by reduced, mucin hypersecretion is lessened, gene activity subsequently regulated prevent infections. biogenic synthesis (AgNPs) using various plants applications antibacterial, antifungal, antioxidant, anticancer, anti-inflammatory, antidiabetic activities been extensively discussed this article. Also, because only natural substances utilized manufacturing process, particles that created naturally coated, stabilized, play vital role these biomedical actions. characterization AgNPs, possibility preparing AgNPSs different shapes biological method impact on functions toxicities, size, shape other properties toxicity profiles, limitations, future prospects green-mediated also reported study. major goal study provide readers comprehensive, informed, up-to-date summary production methods under-investigational antidiabetic, antifungal anti-inflammatory properties. This review provides instructions suggestions additional studies based AgNPs. evaluation pushes researchers look resources like plant parts create useful nanobiotechnology.
Язык: Английский
Процитировано
24
Nano-Structures & Nano-Objects, Год журнала: 2024, Номер 38, С. 101175 - 101175
Опубликована: Май 1, 2024
Язык: Английский
Процитировано
18
RSC Advances, Год журнала: 2025, Номер 15(5), С. 3858 - 3903
Опубликована: Янв. 1, 2025
A sustainable and viable alternative for conventional chemical physical approaches is the green production of silver nanoparticles (SNPs) using plant extracts.
Язык: Английский
Процитировано
6
Small, Год журнала: 2025, Номер unknown
Опубликована: Янв. 5, 2025
Abstract Bacterial infections are a significant obstacle to the healing of acute and chronic wounds, such as diabetic ulcers burn injuries. Traditional antibiotics primary treatment for bacterial infections, but they present issues antibiotic resistance, limited efficacy, potential side effects. This challenge leads exploration nanozymes alternative therapeutic agents. Nanozymes nanomaterials with enzyme‐like activities. Owing their low production costs, high stability, scalability, multifunctionality, have emerged prominent focus in antimicrobial research. Among various types nanozymes, metal‐based offer several benefits, including broad‐spectrum activity robust catalytic properties. Specifically, copper‐based (CuNZs) shown considerable promoting wound healing. They exhibit strong effects, reduce inflammation, enhance tissue regeneration, making them highly advantageous use care. review describes dual functions CuNZs combating infection facilitating repair. Recent advancements design synthesis CuNZs, evaluating promotion, biosafety both vitro vivo on basis core components, critically important.
Язык: Английский
Процитировано
2