Phytochemical Importance of Medicinal Plants as Potential Sources Against Neurodegenerative Diseases

Опубликована: Янв. 1, 2024

Язык: Английский

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Research Progress on the Mechanism of Massage in Regulating Immune Function

Journal of Contemporary Medical Practice, Год журнала: 2024, Номер 6(8), С. 221 - 227

Опубликована: Авг. 21, 2024

Massage, as a non-invasive and natural therapy, acts on specific parts of the human body through manual techniques to regulate organ function, unblock meridians, promote qi circulation blood circulation, demonstrating positive regulatory effect immune function. This article comprehensively analyzes effects massage activity cells, regulation molecule secretion, improvement system. Research has revealed that may exert its various mechanisms such neuroendocrine regulation, cellular signaling pathways, oxidative stress antioxidant balance, non coding RNA microbial community regulation. Intended provide scientific basis for further research clinical application therapy.

Язык: Английский

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Integrated analysis of lncRNA-miRNA-mRNA ceRNA network in neurodegenerative diseases

Neuroscience Informatics, Год журнала: 2024, Номер unknown, С. 100176 - 100176

Опубликована: Сен. 1, 2024

Язык: Английский

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Different intensities of physical activity for amyotrophic lateral sclerosis and Parkinson disease: A Mendelian randomization study and meta-analysis

Medicine, Год журнала: 2024, Номер 103(44), С. e40141 - e40141

Опубликована: Ноя. 1, 2024

Background: The causal relationships between amyotrophic lateral sclerosis (ALS), Parkinson disease and different intensities of physical activity (PA) are still inconclusive. To evaluate the impact PA on ALS (PD), this study integrates evidence from Mendelian randomization (MR) using a meta-analysis approach. Methods: MR analyses genetically predicted levels (compose self-reported moderate-to-vigorous [MVPA], vigorous [VPA], strenuous sports or other exercises [SSOE]) regarding PD published up to July 27, 2024, were obtained PubMed, Scopus, Web Science, Embase. De novo studies analyzed utilizing publicly accessible datasets genome-wide association then meta-analyses performed pool results. Results: Meta-analyses results 12 de 2 indicated that genetic MVPA (odds ratio [OR]: 1.22, 95% confidence interval [CI]: 1.08–1.38), VPA (OR: 1.32, CI: 1.08–1.60), SSOE 1.35, 1.07–1.70) related raised risk ALS, but not causally with PD. Conclusion: Our findings showed no MVPA, VPA, SSOE, PD, while associated increased risk, highlighting need for targeted recommendations management.

Язык: Английский

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ВИРУСО-ЭПИГЕНЕТИЧЕСКАЯ ГИПОТЕЗА ЭТИОПАТОГЕНЕЗА БОЛЕЗНИ ПАРКИНСОНА

Успехи геронтологии, Год журнала: 2024, Номер 37(5), С. 499 - 507

Опубликована: Дек. 23, 2024

Язык: Русский

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