Phytochemical Importance of Medicinal Plants as Potential Sources Against Neurodegenerative Diseases

Published: Jan. 1, 2024

Language: Английский

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Research Progress on the Mechanism of Massage in Regulating Immune Function

Journal of Contemporary Medical Practice, Journal Year: 2024, Volume and Issue: 6(8), P. 221 - 227

Published: Aug. 21, 2024

Massage, as a non-invasive and natural therapy, acts on specific parts of the human body through manual techniques to regulate organ function, unblock meridians, promote qi circulation blood circulation, demonstrating positive regulatory effect immune function. This article comprehensively analyzes effects massage activity cells, regulation molecule secretion, improvement system. Research has revealed that may exert its various mechanisms such neuroendocrine regulation, cellular signaling pathways, oxidative stress antioxidant balance, non coding RNA microbial community regulation. Intended provide scientific basis for further research clinical application therapy.

Language: Английский

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Integrated analysis of lncRNA-miRNA-mRNA ceRNA network in neurodegenerative diseases

Neuroscience Informatics, Journal Year: 2024, Volume and Issue: unknown, P. 100176 - 100176

Published: Sept. 1, 2024

Language: Английский

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Different intensities of physical activity for amyotrophic lateral sclerosis and Parkinson disease: A Mendelian randomization study and meta-analysis

Medicine, Journal Year: 2024, Volume and Issue: 103(44), P. e40141 - e40141

Published: Nov. 1, 2024

Background: The causal relationships between amyotrophic lateral sclerosis (ALS), Parkinson disease and different intensities of physical activity (PA) are still inconclusive. To evaluate the impact PA on ALS (PD), this study integrates evidence from Mendelian randomization (MR) using a meta-analysis approach. Methods: MR analyses genetically predicted levels (compose self-reported moderate-to-vigorous [MVPA], vigorous [VPA], strenuous sports or other exercises [SSOE]) regarding PD published up to July 27, 2024, were obtained PubMed, Scopus, Web Science, Embase. De novo studies analyzed utilizing publicly accessible datasets genome-wide association then meta-analyses performed pool results. Results: Meta-analyses results 12 de 2 indicated that genetic MVPA (odds ratio [OR]: 1.22, 95% confidence interval [CI]: 1.08–1.38), VPA (OR: 1.32, CI: 1.08–1.60), SSOE 1.35, 1.07–1.70) related raised risk ALS, but not causally with PD. Conclusion: Our findings showed no MVPA, VPA, SSOE, PD, while associated increased risk, highlighting need for targeted recommendations management.

Language: Английский

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ВИРУСО-ЭПИГЕНЕТИЧЕСКАЯ ГИПОТЕЗА ЭТИОПАТОГЕНЕЗА БОЛЕЗНИ ПАРКИНСОНА

Успехи геронтологии, Journal Year: 2024, Volume and Issue: 37(5), P. 499 - 507

Published: Dec. 23, 2024

Language: Русский

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