Journal of Hazardous Materials, Год журнала: 2024, Номер 480, С. 136120 - 136120
Опубликована: Окт. 9, 2024
Язык: Английский
The Lancet Planetary Health, Год журнала: 2023, Номер 7(10), С. e831 - e840
Опубликована: Сен. 12, 2023
Lead exposure is a worldwide health risk despite substantial declines in blood lead levels following the leaded gasoline phase-out. For first time, to our knowledge, we aimed estimate global burden and cost of intelligence quotient (IQ) loss cardiovascular disease mortality from exposure.In this modelling study, used country level estimates Global Burden Diseases, Injuries, Risk Factors Study (GBD) 2019. We estimated IQ (presented as points with 95% CIs) population children younger than 5 years using level-IQ function an international pooled analysis. loss, which was calculated only for proportion expected enter labour force, present value lifetime income US dollars percentage gross domestic product range). deaths (with due among people aged 25 or older impact model that captures effect on mediated through mechanisms other hypertension. Finally, values statistical life welfare premature GDP). All were by World Bank classification region (for low-income middle-income countries [LMICs] only) 2019.We lost 765 million (95% CI 443-1098) 545 000 (2 305 000-8 271 000) adults died 2019 exposure. 729 (95·3% total loss) 004 (90·2% total) occurred LMICs. LMICs nearly 80% higher previous estimate. Cardiovascular six times GBD The US$6·0 trillion (range 2·6-9·0) 2019, equivalent 6·9% (3·1-10·4) product. 77% 70-78) mortality, 23% (22-30) future losses loss.Our findings suggest has economic costs at par PM2·5 air pollution. However, much work remains improve quality measurement data, especially LMICs.The Korea Green Growth Trust Fund Bank's Pollution Management Environmental Health Program.
Язык: Английский
Процитировано
85
Circulation Research, Год журнала: 2024, Номер 134(9), С. 1160 - 1178
Опубликована: Апрель 25, 2024
Heavy metals are harmful environmental pollutants that have attracted widespread attention due to their health hazards human cardiovascular disease. metals, including lead, cadmium, mercury, arsenic, and chromium, found in various sources such as air, water, soil, food, industrial products. Recent research strongly suggests a connection between disease exposure toxic heavy metals. Epidemiological, basic, clinical studies revealed can promote the production of reactive oxygen species, which then exacerbate species generation induce inflammation, resulting endothelial dysfunction, lipid metabolism distribution, disruption ion homeostasis, epigenetic changes. Over time, metal eventually results an increased risk hypertension, arrhythmia, atherosclerosis. Strengthening public prevention application chelation or antioxidants, vitamins beta-carotene, along with minerals, selenium zinc, diminish burden attributable exposure.
Язык: Английский
Процитировано
67
Environmental Pollution, Год журнала: 2024, Номер 345, С. 123462 - 123462
Опубликована: Янв. 29, 2024
Exposure to toxic metals is a global public health threat. Among other adverse effects, exposure the heavy metal cadmium has been associated with greater risk of cardiovascular disease (CVD). Nonetheless, shape association between and CVD not clear. This systematic review summarizes data on using dose-response approach. We carried out literature search in PubMed, Web Science, Embase from inception December 30, 2023. Inclusion criteria were: studies adult populations, assessment exposure, overall main subgroups as endpoints, observational study design (cohort, cross-sectional, or case-control). retrieved 26 eligible published during 2005–2023, measuring mainly urine whole blood. In meta-analysis one-stage method within random-effects model, we observed positive CVD. When blood biomarker, was linear, yielding rate ratio (RR) 2.58 (95 % confidence interval-CI 1.78–3.74) at 1 μg/L. urinary linear until 0.5 μg/g creatinine (RR = 2.79, 95 CI 1.26–6.16), after which plateaued. found similar patterns mortality risks heart failure, coronary disease, stroke, whereas for ischemic stroke there only. Overall, our results suggest that whether measured blood, increased risk, further highlighting importance reducing environmental pollution this metal.
Язык: Английский
Процитировано
35
Circulation, Год журнала: 2024, Номер 149(16), С. 1298 - 1314
Опубликована: Апрель 15, 2024
Urban environments contribute substantially to the rising burden of cardiometabolic diseases worldwide. Cities are complex adaptive systems that continually exchange resources, shaping exposures relevant human health such as air pollution, noise, and chemical exposures. In addition, urban infrastructure provisioning influence multiple domains risk, including behaviors, psychological stress, nutrition through various pathways (eg, physical inactivity, heat food systems, availability green space, contaminant exposures). Beyond health, city design may also affect climate change energy material consumption share many same drivers with diseases. Integrated spatial planning focusing on developing sustainable compact cities could simultaneously create heart-healthy environmentally healthy designs. This article reviews current evidence associations between exposome (totality a person experiences, environmental, occupational, lifestyle, social, factors) within science framework, examines principles connectivity, density, diversity land use, destination accessibility, distance transit). We highlight critical knowledge gaps regarding built-environment feature thresholds for optimizing outcomes. Last, we discuss emerging models metrics align development dual goals mitigating while reducing cross-sector collaboration, governance, community engagement. review demonstrates represent crucial settings implementing policies interventions tackle global epidemics cardiovascular disease change.
Язык: Английский
Процитировано
21
Circulation Research, Год журнала: 2024, Номер 134(9), С. 1048 - 1060
Опубликована: Апрель 25, 2024
Environmental stressors associated with human activities (eg, air and noise pollution, light disturbance at night) climate change heat, wildfires, extreme weather events) are increasingly recognized as contributing to cardiovascular morbidity mortality. These harmful exposures have been shown elicit changes in stress responses, circadian rhythms, immune cell activation, oxidative stress, well traditional risk factors hypertension, diabetes, obesity) that promote diseases. In this overview, we summarize evidence from animal studies of the impacts environmental on health. addition, discuss strategies reduce impact current future disease burden, including urban planning, personal monitoring, mitigation measures.
Язык: Английский
Процитировано
19
JACC Advances, Год журнала: 2024, Номер 3(2), С. 100815 - 100815
Опубликована: Янв. 4, 2024
With a growing body of evidence that now links environmental pollution to adverse cardiovascular disease (CVD) outcomes, has emerged as an important risk factor for CVD. There is thus urgent need better understand the role in CVD, key pathophysiological mechanisms, and raise awareness among health care providers, scientific community, general population, regulatory authorities about CV impact strategies reduce it. This article part 2 2-part state-of-the-art review on topic CVD-herein we discuss major pollutants their effects highlighting CVD risk.
Язык: Английский
Процитировано
16
Lipids in Health and Disease, Год журнала: 2025, Номер 24(1)
Опубликована: Фев. 13, 2025
Язык: Английский
Процитировано
3
Sustainability, Год журнала: 2023, Номер 15(16), С. 12413 - 12413
Опубликована: Авг. 15, 2023
The intensification of agricultural production in response to the global population increase and growing demand for food has raised significant concerns regarding environmental impacts over past few decades. Currently, modern agriculture aims improve quantity quality crop yield, minimizing negative effects treatments on environment. Recently, microalgae have found extensive application as a valuable biological resource across multiple industries, including sector, biofuel production, pharmaceutical industry. In agriculture, been seen promising sustainable alternative agrochemicals, offering range benefits soil fertility, optimize nutrient management, reduce reliance synthetic fertilizers. general, demonstrated efficient cycling abilities, assimilating converting essential nutrients, such nitrogen, phosphorus, potassium, into forms readily available plants. Additionally, they produce bioactive substances, phytohormones, which direct impact physiological processes plants promote their growth. Microalgae can also establish beneficial interactions with other microorganisms, supporting growth bacteria fungi, thus promoting healthy microbiome. On hand, photosynthetic harness sunlight convert carbon dioxide (CO2) organic matter through photosynthesis. This ability allows them sequester contribute by reducing greenhouse gas emissions. present work provides an overview potential biofertilizers, highlighting unique characteristics, benefits, main limitations effective implementation agriculturally practices.
Язык: Английский
Процитировано
39
The Lancet, Год журнала: 2024, Номер 404(10462), С. 1561 - 1614
Опубликована: Окт. 1, 2024
Язык: Английский
Процитировано
15
Pathology - Research and Practice, Год журнала: 2024, Номер 256, С. 155260 - 155260
Опубликована: Март 11, 2024
Язык: Английский
Процитировано
9