Hippocampal-occipital connectivity reflects autobiographical memory deficits in aphantasia DOI Creative Commons
Merlin Monzel, Pitshaporn Leelaarporn,

Teresa Lutz

и другие.

eLife, Год журнала: 2024, Номер 13

Опубликована: Сен. 26, 2024

Aphantasia refers to reduced or absent visual imagery. While most of us can readily recall decade-old personal experiences (autobiographical memories, AM) with vivid mental images, there is a dearth information about whether the loss imagery in aphantasics affects their AM retrieval. The hippocampus thought be crucial hub brain-wide network underlying AM. One important question this network, especially connectivity hippocampus, altered aphantasia. In current study, we tested 14 congenital and 16 demographically matched controls an fMRI task investigate how key brain regions (i.e. visual-perceptual cortices) interact each other during re-experiencing. All participants were interviewed regarding autobiographical memory examine episodic semantic specific events. Aphantasics reported more difficulties recalling AM, less confident described internal emotional details than controls. Neurally, displayed decreased hippocampal increased cortex activation retrieval compared addition, showed strong negative functional between resting-state these two structures predicted better visualization skills. Our results indicate that plays role detail-rich type cognitive function supported by connection cortex.

Язык: Английский

Specialization of the human hippocampal long axis revisited DOI Creative Commons
Peter A. Angeli, Lauren M. DiNicola, Noam Saadon‐Grosman

и другие.

Proceedings of the National Academy of Sciences, Год журнала: 2025, Номер 122(3)

Опубликована: Янв. 14, 2025

The hippocampus possesses anatomical differences along its long axis. Here, we explored the functional specialization of human hippocampal axis using network-anchored precision MRI in two independent datasets (N = 11 and N 9) paired with behavioral analysis 266 238). Functional connectivity analyses demonstrated that anterior was preferentially correlated a cerebral network associated remembering, while posterior selectively contained region distinct salience. Seed regions placed within recapitulated networks. characterization task data identified replicated double dissociation. sensitive to remembering imagining future, specifically tracking process scene construction, displayed transient responses targets an oddball detection transitions between blocks. These findings suggest unexpected differential reflecting properties partner

Язык: Английский

Процитировано

6
Hippocampal-occipital connectivity reflects autobiographical memory deficits in aphantasia DOI Creative Commons
Merlin Monzel, Pitshaporn Leelaarporn,

Teresa Lutz

и другие.

eLife, Год журнала: 2024, Номер 13

Опубликована: Фев. 27, 2024

Aphantasia refers to reduced or absent visual imagery. While most of us can readily recall decade-old personal experiences (autobiographical memories, AM) with vivid mental images, there is a dearth information about whether the loss imagery in aphantasics affects their AM retrieval. The hippocampus thought be crucial hub brain-wide network underlying AM. One important question this network, especially connectivity hippocampus, altered aphantasia. In current study, we tested 14 congenital and 16 demographically matched controls an fMRI task investigate how key brain regions (i.e. visual-perceptual cortices) interact each other during re-experiencing. All participants were interviewed regarding autobiographical memory examine episodic semantic specific events. Aphantasics reported more difficulties recalling AM, less confident described internal emotional details than controls. Neurally, displayed decreased hippocampal increased cortex activation retrieval compared addition, showed strong negative functional between resting-state these two structures predicted better visualization skills. Our results indicate that plays role detail-rich type cognitive function supported by connection cortex.

Язык: Английский

Процитировано

8
From single scenes to extended scenarios: the role of the ventromedial prefrontal cortex in the construction of imagery-rich events DOI Creative Commons
Julia Taube, Pitshaporn Leelaarporn,

Maren Bilzer

и другие.

bioRxiv (Cold Spring Harbor Laboratory), Год журнала: 2025, Номер unknown

Опубликована: Май 5, 2025

Abstract Mental events are fundamental to daily cognition, including the recollection of past experiences, anticipation future scenarios, and engagement in imaginative, fictitious thought. Typically, these temporally extended mental unfold within coherent spatial contexts, rich naturalistic scenes objects. However, there remains a significant gap understanding how represented brain. This study aimed investigate neural patterns involved construction events. Using ultra-high field functional magnetic resonance imaging, we examined brain regions previously implicated this cognitive process, ventromedial prefrontal cortex (vmPFC), hippocampus, posterior neocortex. We employed novel experimental paradigm which participants engaged three forms imagery: single objects (e.g., “a black espresso”), busy café”), scenarios “meeting friend for coffee”). identified shared network - comprising vmPFC, neocortex – across all imagery. observed hierarchical organization their contributions: supported objects, scenes, while hippocampus primarily contributed scenarios. The vmPFC exhibited stepwise increase activation, peaking during scenario construction. These findings suggest that emerges from close interaction perceptual details provided by neocortex, coherence integration those elements into coherent, event “movies” mind.

Язык: Английский

Процитировано

0
Hippocampal-occipital connectivity reflects autobiographical memory deficits in aphantasia DOI Creative Commons
Merlin Monzel, Pitshaporn Leelaarporn,

Teresa Lutz

и другие.

bioRxiv (Cold Spring Harbor Laboratory), Год журнала: 2023, Номер unknown

Опубликована: Авг. 13, 2023

Abstract Aphantasia refers to reduced or absent visual imagery. While most of us can readily recall decade-old personal experiences (autobiographical memories, AM) with vivid mental images, there is a dearth information about whether the loss imagery in aphantasics affects their AM retrieval. The hippocampus thought be crucial hub brain-wide network underlying AM. One important question this network, especially connectivity hippocampus, altered aphantasia. In current study, we tested 14 congenital and 16 demographically matched controls an fMRI task investigate how key brain regions (i.e., visual-perceptual cortices) interact each other during re-experiencing. All participants were interviewed regarding autobiographical memory examine episodic semantic specific events. Aphantasics reported more difficulties recalling AM, less confident described internal emotional details than controls. Neurally, displayed decreased hippocampal increased cortex activation retrieval compared addition, showed strong negative functional between resting-state these two structures predicted better visualization skills. Our results indicate that plays role detail-rich type cognitive function supported by connection cortex.

Язык: Английский

Процитировано

4
Hippocampal-occipital connectivity reflects autobiographical memory deficits in aphantasia DOI Creative Commons
Merlin Monzel, Pitshaporn Leelaarporn,

Teresa Lutz

и другие.

eLife, Год журнала: 2024, Номер 13

Опубликована: Сен. 26, 2024

Aphantasia refers to reduced or absent visual imagery. While most of us can readily recall decade-old personal experiences (autobiographical memories, AM) with vivid mental images, there is a dearth information about whether the loss imagery in aphantasics affects their AM retrieval. The hippocampus thought be crucial hub brain-wide network underlying AM. One important question this network, especially connectivity hippocampus, altered aphantasia. In current study, we tested 14 congenital and 16 demographically matched controls an fMRI task investigate how key brain regions (i.e. visual-perceptual cortices) interact each other during re-experiencing. All participants were interviewed regarding autobiographical memory examine episodic semantic specific events. Aphantasics reported more difficulties recalling AM, less confident described internal emotional details than controls. Neurally, displayed decreased hippocampal increased cortex activation retrieval compared addition, showed strong negative functional between resting-state these two structures predicted better visualization skills. Our results indicate that plays role detail-rich type cognitive function supported by connection cortex.

Язык: Английский

Процитировано

1