Hippocampal-occipital connectivity reflects autobiographical memory deficits in aphantasia DOI Creative Commons
Merlin Monzel, Pitshaporn Leelaarporn,

Teresa Lutz

et al.

eLife, Journal Year: 2024, Volume and Issue: 13

Published: Sept. 26, 2024

Aphantasia refers to reduced or absent visual imagery. While most of us can readily recall decade-old personal experiences (autobiographical memories, AM) with vivid mental images, there is a dearth information about whether the loss imagery in aphantasics affects their AM retrieval. The hippocampus thought be crucial hub brain-wide network underlying AM. One important question this network, especially connectivity hippocampus, altered aphantasia. In current study, we tested 14 congenital and 16 demographically matched controls an fMRI task investigate how key brain regions (i.e. visual-perceptual cortices) interact each other during re-experiencing. All participants were interviewed regarding autobiographical memory examine episodic semantic specific events. Aphantasics reported more difficulties recalling AM, less confident described internal emotional details than controls. Neurally, displayed decreased hippocampal increased cortex activation retrieval compared addition, showed strong negative functional between resting-state these two structures predicted better visualization skills. Our results indicate that plays role detail-rich type cognitive function supported by connection cortex.

Language: Английский

Specialization of the human hippocampal long axis revisited DOI Creative Commons
Peter A. Angeli, Lauren M. DiNicola, Noam Saadon‐Grosman

et al.

Proceedings of the National Academy of Sciences, Journal Year: 2025, Volume and Issue: 122(3)

Published: Jan. 14, 2025

The hippocampus possesses anatomical differences along its long axis. Here, we explored the functional specialization of human hippocampal axis using network-anchored precision MRI in two independent datasets (N = 11 and N 9) paired with behavioral analysis 266 238). Functional connectivity analyses demonstrated that anterior was preferentially correlated a cerebral network associated remembering, while posterior selectively contained region distinct salience. Seed regions placed within recapitulated networks. characterization task data identified replicated double dissociation. sensitive to remembering imagining future, specifically tracking process scene construction, displayed transient responses targets an oddball detection transitions between blocks. These findings suggest unexpected differential reflecting properties partner

Language: Английский

Citations

4
Hippocampal-occipital connectivity reflects autobiographical memory deficits in aphantasia DOI Creative Commons
Merlin Monzel, Pitshaporn Leelaarporn,

Teresa Lutz

et al.

eLife, Journal Year: 2024, Volume and Issue: 13

Published: Feb. 27, 2024

Aphantasia refers to reduced or absent visual imagery. While most of us can readily recall decade-old personal experiences (autobiographical memories, AM) with vivid mental images, there is a dearth information about whether the loss imagery in aphantasics affects their AM retrieval. The hippocampus thought be crucial hub brain-wide network underlying AM. One important question this network, especially connectivity hippocampus, altered aphantasia. In current study, we tested 14 congenital and 16 demographically matched controls an fMRI task investigate how key brain regions (i.e. visual-perceptual cortices) interact each other during re-experiencing. All participants were interviewed regarding autobiographical memory examine episodic semantic specific events. Aphantasics reported more difficulties recalling AM, less confident described internal emotional details than controls. Neurally, displayed decreased hippocampal increased cortex activation retrieval compared addition, showed strong negative functional between resting-state these two structures predicted better visualization skills. Our results indicate that plays role detail-rich type cognitive function supported by connection cortex.

Language: Английский

Citations

8
Hippocampal-occipital connectivity reflects autobiographical memory deficits in aphantasia DOI Creative Commons
Merlin Monzel, Pitshaporn Leelaarporn,

Teresa Lutz

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2023, Volume and Issue: unknown

Published: Aug. 13, 2023

Abstract Aphantasia refers to reduced or absent visual imagery. While most of us can readily recall decade-old personal experiences (autobiographical memories, AM) with vivid mental images, there is a dearth information about whether the loss imagery in aphantasics affects their AM retrieval. The hippocampus thought be crucial hub brain-wide network underlying AM. One important question this network, especially connectivity hippocampus, altered aphantasia. In current study, we tested 14 congenital and 16 demographically matched controls an fMRI task investigate how key brain regions (i.e., visual-perceptual cortices) interact each other during re-experiencing. All participants were interviewed regarding autobiographical memory examine episodic semantic specific events. Aphantasics reported more difficulties recalling AM, less confident described internal emotional details than controls. Neurally, displayed decreased hippocampal increased cortex activation retrieval compared addition, showed strong negative functional between resting-state these two structures predicted better visualization skills. Our results indicate that plays role detail-rich type cognitive function supported by connection cortex.

Language: Английский

Citations

4
Hippocampal-occipital connectivity reflects autobiographical memory deficits in aphantasia DOI Creative Commons
Merlin Monzel, Pitshaporn Leelaarporn,

Teresa Lutz

et al.

eLife, Journal Year: 2024, Volume and Issue: 13

Published: Sept. 26, 2024

Aphantasia refers to reduced or absent visual imagery. While most of us can readily recall decade-old personal experiences (autobiographical memories, AM) with vivid mental images, there is a dearth information about whether the loss imagery in aphantasics affects their AM retrieval. The hippocampus thought be crucial hub brain-wide network underlying AM. One important question this network, especially connectivity hippocampus, altered aphantasia. In current study, we tested 14 congenital and 16 demographically matched controls an fMRI task investigate how key brain regions (i.e. visual-perceptual cortices) interact each other during re-experiencing. All participants were interviewed regarding autobiographical memory examine episodic semantic specific events. Aphantasics reported more difficulties recalling AM, less confident described internal emotional details than controls. Neurally, displayed decreased hippocampal increased cortex activation retrieval compared addition, showed strong negative functional between resting-state these two structures predicted better visualization skills. Our results indicate that plays role detail-rich type cognitive function supported by connection cortex.

Language: Английский

Citations

1