Cited by The association of positive emotions with absenteeism and presenteeism in Japanese workers

Further elucidation of GMPPB as a risk gene for depression through integrative multi-omics analyses DOI

Yanhong Du,

Yao Gao,

Xinzhe Du

и другие.

Journal of Affective Disorders, Год журнала: 2025, Номер unknown

Опубликована: Май 1, 2025

Язык: Английский

Процитировано

Karen Lin, Karin Hasegawa,

Vindhya Rani Rapelli

и другие.

Research Square (Research Square), Год журнала: 2025, Номер unknown

Опубликована: Май 8, 2025

The link between obesity and depression is bidirectional antidepressant efficacy reduced in obese individuals. To probe this mechanism, anthropometric measures (body mass index [BMI] waist circumference [WC]) from 85 participants (n = 56 females, n 29 males) with Major Depressive Disorder (MDD) were acquired. Participants then received simultaneous positron emission tomography (PET)/magnetic resonance imaging (MRI) before after treatment a double-blind randomized trial of escitalopram. Linear mixed models used to examine the association continuous categorical pretreatment amygdala hippocampus volumes metabolism, controlling for covariates. Similar assessed percent change brain volume metabolism treatment, type. Pretreatment, was significantly positively associated (p 0.0160 0.0154, WC BMI, respectively) 0.0221 BMI) volume, but not metabolism. With each additional inch (or lb/in 2 -0.38% -0.26%) treatment-induced volume. In fact, past 37.29 (border increased risk males, substantially females) or 30.63 (obese range), shifts positive (increasing) negative (decreasing). Further, every 1 there 1.03% (amygdala) 0.99% (hippocampus) increase treatment. This multimodal study first suggests that obesity-related factors may alter structure hippocampus, potentially reducing effectiveness MDD.

Язык: Английский

Процитировано

Nutrition and Neuroinflammation: Are Middle-Aged Women in the Red Zone? DOI

Veronique Bernier,

Angéline Chatelan,

Camille Point

и другие.

Nutrients, Год журнала: 2025, Номер 17(10), С. 1607 - 1607

Опубликована: Май 8, 2025

Women exhibit unique vulnerabilities in health, especially regarding mental health and neurodegenerative diseases. Biological, hormonal, metabolic differences contribute to sex-specific risks that remain underrepresented clinical studies. Diseases such as major depressive disorder (MDD) Alzheimer’s disease (AD) are more prevalent women may be influenced by hormonal transitions, particularly during menopause. Chronic low-grade inflammation is emerging a shared mechanism underlying both conditions, this inflammatory state can worsened dietary habits. During menopause, mood sleep disturbances influence behavior, leading enhanced snacking consumption of high-glycemic comfort foods. Such foods, low nutritional value, promote weight gain elevated markers. Their combined (or not) with preexisting Western diet pattern—already linked inflammation—could reinforce systemic involving the gut–brain axis. Moreover, symptoms “per se” could act on well. Peripheral cross blood–brain barrier, sustaining disorders promoting changes. Finally, MDD AD associated conditions obesity diabetes, which occur frequently women. The review highlights how menopause-related changes mood, sleep, heighten susceptibility

Язык: Английский

Процитировано

Fasting blood glucose mediated the association between a body shape index and depression: a cross sectional study from NHANES 2017–2023 DOI

Y.‐H. Chen, Christine Wei, Z. Wang

и другие.

Frontiers in Nutrition, Год журнала: 2025, Номер 12

Опубликована: Май 9, 2025

Objective The objective was to evaluate ABSI’s association with depression and explore FBG as a possible mediating factor. Methods Data from 8,748 NHANES participants (2017–2023) were analyzed. Logistic regression analyses assessed ABSI-depression associations, while mediation models tested FBG’s intermediary role. We conducted stratified interaction test assess the impact of gender, age, race, PIR, education, alcohol use, current smoking status, BMI, hypertension history hypercholesterolemia on study outcomes. Results fully adjusted logistic demonstrated significant positive between ABSI (OR = 1.20, 95%CI: 1.00, 1.44, p 0.0497). Stratified showed that this only among some college education or above (P for < 0.05). No interactions found across other subgroups. Mediation revealed partially mediated relationship (15.8%, 0.0001). Conclusion associated depression, potentially through FBG.

Язык: Английский

Процитировано

The association of positive emotions with absenteeism and presenteeism in Japanese workers DOI

Chong Chen, Ryo Okubo, Kosuke Hagiwara

и другие.

Journal of Affective Disorders, Год журнала: 2023, Номер 344, С. 319 - 324

Опубликована: Окт. 14, 2023

Язык: Английский

Процитировано