The Relationship Between Reduced Hand Dexterity and Brain Structure Abnormality in Older Adults DOI Creative Commons
Anna Manelis, Hang Hu, Skye Satz

и другие.

Geriatrics, Год журнала: 2024, Номер 9(6), С. 165 - 165

Опубликована: Дек. 17, 2024

Background: Hand dexterity is affected by normal aging and neuroinflammatory processes in the brain. Understanding relationship between hand brain structure neurotypical older adults may be informative about prodromal pathological processes, thus providing an opportunity for earlier diagnosis intervention to improve functional outcomes. Methods: this study investigates associations measures (≥65 years) using Nine-Hole Peg Test (9HPT) magnetic resonance imaging (MRI). Results: Elastic net regularized regression revealed that reduced dominant non-dominant hands was associated with enlarged volume of left choroid plexus, region implicated altered myelination myelin content frontal operculum, motor imagery, action production, higher-order functions. Distinct neural mechanisms underlying included differences caudate thalamic volumes as well cortical patterns frontal, temporal, parietal, occipital regions supporting sensorimotor visual processing integration, attentional control, eye movements. Although elastic identified more predictive features vs. hand, feature stability higher latter, indicating generalizability model. Conclusions: Our findings suggest 9HPT might a cost-effective screening tool early detection neurodegenerative processes. Longitudinal studies are needed validate our larger sample explore potential clinical marker.

Язык: Английский

Age bias in changes in finger dexterity based on brain activation and spinal motor nerve excitability induced by motor imagery practice DOI
Yuki Fukumoto,

Hiroki Bizen,

Marina Todo

и другие.

Neuroscience, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

Язык: Английский

Процитировано

0
Construction and evaluation of a finger motor feedback system to improve finger dexterity DOI Creative Commons
Shingo Takahashi,

Noriko Sakurai,

Yuki Kuroiwa

и другие.

Frontiers in Neuroergonomics, Год журнала: 2025, Номер 6

Опубликована: Фев. 26, 2025

Recently, a link has been established between cognitive function and hand dexterity in older adults. Declines have shown to impair performance finger tapping movements. Research suggest that training can improve dexterity, executive function, over time. This underscores the need for effective methods dexterity. In this study, we introduced new system provides real-time feedback on movements during tasks. We examined system's impact of 32 healthy young participants by using magnetic sensor device (UB-2). During task, performed opening closing either in-phase or anti-phase both left right hands 15 s. They were instructed tap as quickly possible. The number taps, left-right balance, other relevant data measured UB-2 device. terms tapping, significant difference was found 64.4 without 68.1 with simultaneous dominant hand. alternating open-close movement, 50.3 53.4 feedback. results showed significantly improved frequency taps hands. suggests

Язык: Английский

Процитировано

0
Multi-task exercise increases delta power in non-rapid eye movement sleep among older female adults: a randomized crossover trial DOI Creative Commons
Jaehee Lee, Koki Nagata, Jaehoon Seol

и другие.

NeuroImage, Год журнала: 2025, Номер unknown, С. 121105 - 121105

Опубликована: Фев. 1, 2025

Язык: Английский

Процитировано

0
Don't plan, just do it: Cognitive and sensorimotor contributions to manual dexterity DOI Creative Commons
Laura Bonzano, Monica Biggio, Sabrina Brigadoi

и другие.

NeuroImage, Год журнала: 2023, Номер 280, С. 120348 - 120348

Опубликована: Авг. 24, 2023

Manual dexterity is referred to as the skill perform fine motor movements and it has been assumed be associated cognitive domain, well sensorimotor one. In this work, we investigated with functional near-infrared spectroscopy cortical activations elicited by execution of 9-HPT, i.e., a standard test evaluating manual in which nine pegs were taken, placed into then removed from holes on board quickly possible. For comparison, proposed new active control task mainly involving must using same single hole (1-HPT). Behaviorally, found two distinct groups based difference between time 9-HPT 1-HPT (ΔHPT). Cortical areas belonging network controlling reaching grasping both groups; however, participants showing large ΔHPT presented significantly higher activation prefrontal (right BA10 BA11) during performance respect small ΔHPT, who showed deactivation BA10. Unexpectedly, observed significant linear relationship right activity. This suggested that performing more slowly than recruited implicitly exploiting skills planning, perhaps search strategy solve activating attentional processes, but resulted not efficient instead increased accomplish task.

Язык: Английский

Процитировано

5
Bidirectional associations of high-level cognitive domains with hand motor function and gait speed in high-functioning older adults: A 7-year study DOI
Kimi Estela Kobayashi‐Cuya, Ryota Sakurai, Naoko Sakuma

и другие.

Archives of Gerontology and Geriatrics, Год журнала: 2023, Номер 117, С. 105232 - 105232

Опубликована: Окт. 27, 2023

Язык: Английский

Процитировано

5
Construction and evaluation of a neurofeedback system using finger tapping and near-infrared spectroscopy DOI Creative Commons
Shingo Takahashi,

Daishi Takahashi,

Yuki Kuroiwa

и другие.

Frontiers in Neuroimaging, Год журнала: 2024, Номер 3

Опубликована: Апрель 25, 2024

Introduction Neurofeedback using near-infrared spectroscopy (NIRS) has been used in patients with stroke and other patients, but few studies have included older people or cognitive impairment. Methods We constructed a NIRS-based neurofeedback system finger tapping to investigate whether can be implemented adults while brain activity improves healthy participants. Our simple was portable wearable optical topography (WOT-HS) device. Brain evaluated 10 31 young individuals by measuring oxygenated hemoglobin concentration during implementation. Results During neurofeedback, the of increased prefrontal regions both Discussion The results this study demonstrate usefulness NIRS devices for its potential mitigate decline.

Язык: Английский

Процитировано

1
Explaining the influence of practice on the grooved pegboard times of older adults: role of force steadiness DOI

Sajjad Daneshgar,

Taylor Tvrdy,

Roger M. Enoka

и другие.

Experimental Brain Research, Год журнала: 2024, Номер 242(8), С. 1971 - 1982

Опубликована: Июнь 25, 2024

Язык: Английский

Процитировано

1
Hemodynamics of short-duration light-intensity physical exercise in the prefrontal cortex of children: a functional near-infrared spectroscopy study DOI Creative Commons
Takashi Naito, Koichiro Oka, Kaori Ishii

и другие.

Scientific Reports, Год журнала: 2024, Номер 14(1)

Опубликована: Июль 6, 2024

Abstract Identifying the types of exercise that enhance cerebral blood flow is crucial for developing programs cognitive function. Nevertheless, few studies have explored amount light-intensity, short-duration exercises individuals can easily perform on flow, particularly in children. We examined effects these hemodynamics prefrontal cortex (PFC) using functional near-infrared spectroscopy. Participants comprised 41 children (aged 12.1 ± 1.5 years, 37% female) who engaged seven light-intensity exercises, with each movement performed two patterns lasting 10 or 20 s. Changes oxygenated hemoglobin (oxy-Hb) levels at rest and during were compared analysis covariance, sex age as covariates. Significant increases oxy-Hb observed multiple regions PFC all forms (including dynamic twist stretching [66.6%, 8/12 regions, η 2 = 0.07–0.27], hand finger movements [75.0%, 9/12 0.07–0.16], balance (100.0%, 6/6 0.13–0.25]), except static monotonic movements. This study implies short-duration, provided they entail a certain degree and/or physical demands, activate increase flow.

Язык: Английский

Процитировано

1
Differences in working memory function are associated with motor imagery-induced changes in spinal motor nerve excitability and subsequent motor skill changes DOI
Yuki Fukumoto, Keisuke Fujii,

Marina Todo

и другие.

Cognitive Processing, Год журнала: 2024, Номер unknown

Опубликована: Сен. 27, 2024

Язык: Английский

Процитировано

1
The relationship between brain structure and reduced hand dexterity in older adults DOI Creative Commons
Anna Manelis, Hang Hu, Skye Satz

и другие.

medRxiv (Cold Spring Harbor Laboratory), Год журнала: 2024, Номер unknown

Опубликована: Ноя. 12, 2024

ABSTRACT Hand dexterity is affected by normal aging and neuroinflammatory processes in the brain. Understanding relationship between hand brain structure neurotypical older adults may inform about prodromal pathological processes, thus providing an opportunity for earlier diagnosis intervention to improve functional outcomes. This study investigates associations measures (≥65 years) using Nine Hole Peg Test (9HPT) magnetic resonance imaging (MRI). Elastic net regularized regression revealed that reduced dominant non-dominant hands was associated with enlarged volume of left choroid plexus, region implicated altered myelination myelin content frontal operculum, motor imagery, action production, higher-order functions. Distinct neural mechanisms underlying included differences caudate thalamic volumes as well cortical patterns frontal, temporal, parietal, occipital regions supporting sensorimotor visual processing integration, attentional control, eye movements. Although elastic identified more predictive features vs. hand, feature stability higher latter, indicating generalizability model. Our findings suggest 9HPT serve a cost-effective screening tool early detection neurodegenerative processes. Longitudinal studies are needed validate our larger sample explore potential clinical marker.

Язык: Английский

Процитировано

0