Return to Work Up to 5 Years After the End of Treatment Among Patients With Head and Neck Cancer

JAMA Otolaryngology–Head & Neck Surgery, Год журнала: 2025, Номер unknown

Опубликована: Фев. 6, 2025

Importance Adverse effects of cancer and its treatment may hamper return to work (RTW) among patients with head neck (HNC). Objectives To investigate RTW HNC from end 5 years after associations sociodemographic, clinical, work-related, personal, lifestyle, physical, psychological factors cancer-related symptoms. Design, Setting Participants This prospective, longitudinal, multicenter cohort study used data the Netherlands Quality Life Biomedical cohort. focused on younger than 65 (with a subanalysis 60 years) time diagnosis (March 2014 June 2018) (January 2019 July 2023). Data analysis occurred April 2023 August 2024. Exposure Standard clinical care. Main Outcomes Measures Work status was measured at 3 6 months, 1, 2, 3, 4, using an adjusted version Productivity Cost Questionnaire. Cox regression analyses were performed (baseline, months) associated RTW. Results A total 184 (mean [SD] age, 55.4 [7.0] years; 146 men [79%]) included 77 (42%) had oropharyngeal cancer. increased 26% (42 160 individuals) months 65% (89 137 1 year, which it reduced 52% (51 98 years. At treatment, additional 28 participants (29%) retired. Minor surgery (vs major surgery) faster onwards (hazard ratio [HR], 2.73; 95% CI, 1.17-6.37). Older age (HR, 0.97; 0.94-0.999) more fatigue 0.99; 0.98-0.995) slower onwards. also 0.96; 0.93-0.998). Among 127 years, 72% (47 treatment. Advanced tumor stage 0.59; 0.39-0.90) 0.98-0.999) in this group. Conclusion relevance found that majority returned within year certain sociodemographic symptoms These results inform provide insight into potential targets, such as fatigue, improve

Язык: Английский

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Supportive care needs among head and neck cancer patients in the recovery phase from 6 months to 2 years after treatment: which factors matter?

Journal of Cancer Survivorship, Год журнала: 2025, Номер unknown

Опубликована: Фев. 10, 2025

Abstract Purpose To investigate which demographic, personal, clinical, physical, psychological, social, lifestyle, and cancer-related quality of life (QoL) factors are associated with (changes in) supportive care needs (SCNs) from 6 months to 2 years after treatment in head neck cancer (HNC) patients. Methods Data the prospective NETherlands QUality BIomedical Cohort (NET-QUBIC) study among HNC patients treated curative intent was used. SCNs were measured using Supportive Care Needs Survey 34-item Short-Form (SCNS-SF34) (6 months, 1 treatment) 11-item HNC-specific module (SCNS-HNC) (2 years). Multivariable linear mixed model analyses regression used changes over time level at follow-up (SCNS-SF34 SCNS-HNC). Results 483 physical daily living (PDL), psychological (PSY), health system, information, patient support (HSIPS) domains decreased significantly time. At follow-up, highest reported regarding lack energy/tiredness (10.8%). Changes absolute personal clinical post-treatment months) QoL factors. Conclusions Personal, SCNs. These results can be develop predictive models personalize for Implications Cancer Survivors decrease time, but a subgroup still presents treatment.

Язык: Английский

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Evaluation of a psychoneurological symptom cluster in patients with breast or digestive cancer: a longitudinal observational study

BMC Cancer, Год журнала: 2024, Номер 24(1)

Опубликована: Янв. 9, 2024

Abstract Background A psychoneurological symptom cluster composed of cancer-related fatigue, emotional distress, sleep difficulties, and pain is very common among patients with cancer. Cognitive difficulties are also frequently associated this cluster. Network analyses allow for an in-depth understanding the relationships between symptoms in a This paper details study protocol longitudinal assessment two distinct cohorts: breast cancer digestive survivors, using network analyses. Methods Over years, involved cluster, along other (e.g., symptoms, financial difficulties) variables (i.e., self-compassion, coping strategies) will be assessed survivors ( N = 240) 240). Online questionnaires completed at baseline, then 6, 12 24 months later. used to assess configuration each measurement time cohort. Comparison networks times or cohorts done comparison tests. Discussion enable better endured by The results employed develop more cost-effective interventions which, ultimately, significantly improve quality life Trial registration ClinicalTrials.gov (NCT05867966). Registered on 27th April 2023. url: https://classic.clinicaltrials.gov/ct2/show/NCT05867966 .

Язык: Английский

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Caregiver Burden, Psychological Distress and Quality of Life among Informal Caregivers of Patients with Head and Neck Cancer: A Longitudinal Study

International Journal of Environmental Research and Public Health, Год журнала: 2022, Номер 19(23), С. 16304 - 16304

Опубликована: Дек. 5, 2022

(1) Background: The aim of this study was to investigate caregiver burden among informal caregivers head and neck cancer patients, in relation distress quality life (QoL), the relationship between patients. (2) Methods: Data 234 dyads from multicenter prospective cohort Netherlands Quality Biomedical Cohort studies used. Caregiver burden, psychological distress, global QoL, physical social functioning were measured baseline until 24 months after treatment. (4) Conclusions: This shows high caring for HNC impact interaction patient. We suggest that healthcare professionals include counseling support.

Язык: Английский

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Interventions for head and neck cancer survivors: Systematic review

Head & Neck, Год журнала: 2022, Номер 44(11), С. 2579 - 2599

Опубликована: Июль 18, 2022

Abstract Background Interventions for head/neck cancer (HNC) survivors may not address their cancer‐related and general health needs. Methods Preferred Reporting Items Systematic Reviews Meta‐Analysis (PRISMA) guided this systematic review of studies from 2000 to 2021 interventions targeting treated with curative‐intent, using MEDLINE, Embase, Emcare, PsycINFO. were categorized into domains the Quality Cancer Survivorship Care Framework characterize scope quality interventions. Results We identified 28 inclusion: 13 randomized 15 non‐randomized. Most targeted surveillance/management physical effects ( n = 24) including that also psychosocial effects. Four addressed prevention/surveillance recurrence/new cancers, one promotion/disease prevention, chronic medical conditions. 27) had medium‐high risk bias. Conclusions There are few high‐quality addressing HNC survivorship. Future rigorously designed should broader areas care, disease management prevention.

Язык: Английский

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Psychological Problems among Head and Neck Cancer Patients in Relation to Utilization of Healthcare and Informal Care and Costs in the First Two Years after Diagnosis

Current Oncology, Год журнала: 2022, Номер 29(5), С. 3200 - 3214

Опубликована: Апрель 30, 2022

Background: To investigate associations between psychological problems and the use of healthcare informal care total costs among head neck cancer (HNC) patients. Method: Data were used NETherlands QUality Life Biomedical Cohort study. Anxiety depression disorder (diagnostic interview), distress, symptoms anxiety (HADS), fear recurrence (FCR) worry scale (CWS) measured at baseline 12-month follow-up. Care (questionnaire) baseline, 3-, 6-, 12-, 24-month Associations use/costs investigated using logistic multiple regression analyses. Results: 558 patients used. Distress, or depression, FCR, and/or significantly associated with higher primary care, supportive (odds ratios (ORs) 1.55 4.76). Symptoms anxiety, follow-up (ORs 1.74 6.42). FCR costs. Discussion: HNC make more have This is not result worse clinical outcomes.

Язык: Английский

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The course of swallowing problems in the first 2 years after diagnosis of head and neck cancer

Supportive Care in Cancer, Год журнала: 2022, Номер 30(11), С. 9527 - 9538

Опубликована: Авг. 30, 2022

Abstract Introduction Head and neck cancer (HNC) its treatment often negatively impact swallowing function. The aim was to investigate the course of patient-reported problems from diagnosis 3, 6, 12, 24 months after treatment, in relation demographic, clinical, lifestyle factors. Methods Data were used Netherlands Quality Life Biomedical Cohort Study head research (NET-QUBIC). primary outcome measures subscales Swallowing Questionnaire (SWAL-QOL). Linear mixed-effects models (LMM) conducted changes over time associations with patient, parameters as assessed at baseline. Results available 603 patients. There a significant change on all subscales. Before 53% patients reported problems. This number increased 70% M3 decreased 59% M6, 50% M12, 48% M24. (i.e., longer eating duration) more pronounced case female, current smoking, weight loss prior stage III or IV tumor, prevalent 3 6 treatment. Especially an oropharynx oral cavity receiving (C)RT following surgery CRT only showed duration which did not return baseline levels. Conclusion Half HNC report before Eating associated sex, loss, tumor site stage, modality,

Язык: Английский

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The Change in Social Eating over Time in People with Head and Neck Cancer Treated with Primary (Chemo)Radiotherapy: The Role of Swallowing, Oral Function, and Nutritional Status

Cancers, Год журнала: 2023, Номер 15(5), С. 1603 - 1603

Опубликована: Март 4, 2023

This study aimed at investigating the change in social eating problems from diagnosis to 24 months after primary (chemo)radiotherapy and its associations with swallowing, oral function, nutritional status, addition clinical, personal, physical, psychological, social, lifestyle dimensions. Adult patients NETherlands QUality of life BIomedical Cohort (NET-QUBIC) treated curative intent for newly-diagnosed HNC who provided baseline data were included. Social measured 3-, 6-, 12-, 24-month follow-up, hypothesized associated variables 6 months. Associations analyzed through linear mixed models. Included 361 (male: 281 (77.8%), age: mean = 63.3, SD 8.6). increased 3-month follow-up decreased up (F 33.134, p < 0.001). The baseline-to-24 month was swallowing-related quality 9.906, 0.001) symptoms 4.173, 0.002), status 4.692, 0.001), tumor site 2.724, age 3.627, 0.006), depressive 5.914, 6-24-month a 6-month 6.089, 5.727, 0.004), muscle strength 5.218, hearing 5.155, 0.006). Results suggest monitoring until 12-month basing interventions on patients' features.

Язык: Английский

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Clinical outcomes of teeth adjacent to the site of mandibulotomy or mandibulectomy in patients with head and neck cancer: results from a multidisciplinary mono-institutional head and neck tumor board

BMC Oral Health, Год журнала: 2023, Номер 23(1)

Опубликована: Июнь 3, 2023

Abstract Introduction The aim of this case series was to evaluate the necrosis teeth adjacent site mandibulotomy or mandibulectomy in a cohort patients suffering from head and neck cancers. Methods Fourteen who underwent segmental paramedian for oral, oropharynx major salivary gland cancer total 23 were included series. Twelve adjuvant radiotherapy. Cold sensitivity pulp testing and/or electric performed on at margin after surgery. A “positive” response considered healthy state, “negative” diseased state tooth. Results 10 had 12 with negative response. 4 treated by two positive three responses cold tests. Fifteen out (65.2%) showed testing. Conclusions Tooth seems be common event mandibulotomy. Clinical Relevance To avoid post-surgery complications, performing root canal therapy before surgery surgical could an appropriate strategy.

Язык: Английский

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The course of health-related quality of life in the first 2 years after a diagnosis of head and neck cancer: the role of personal, clinical, psychological, physical, social, lifestyle, disease-related, and biological factors

Supportive Care in Cancer, Год журнала: 2023, Номер 31(8)

Опубликована: Июль 11, 2023

The aim of this prospective cohort study was to estimate the relationship between course HRQOL in first 2 years after diagnosis and treatment head neck cancer (HNC) personal, clinical, psychological, physical, social, lifestyle, HNC-related, biological factors.

Язык: Английский

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