Research Square (Research Square),
Год журнала:
2022,
Номер
unknown
Опубликована: Май 18, 2022
Abstract
Objective
Polypharmacy
increases
the
prevalence
of
potentially
inappropriate
drugs
(PIMs)
among
older
persons,
lowering
their
quality
life.
This
study
aimed
to
compare
PIMs
in
Chinese
outpatients
according
Beers
criteria
and
analyze
risk
factors.
Second,
we
describe
differences
between
two
criteria,
focusing
on
prescription
outpatients.
Methods
In
Chengdu,
Southwest
China,
a
retrospective
was
undertaken
using
electronic
medical
data
from
9
institutions.
Outpatients
above
age
60
who
were
treated
Geriatrics
Center
these
institutions
included.
The
used
evaluate
PIM
status
outpatients,
logistic
regression
identify
potential
factors
for
PIMs.
Results
There
44,458
prescriptions
2016
2018.
30.05%
(according
criteria)
35.38%
criteria).
Estazolam,
hydrochlorothiazide
alprazolam
top
three
while
clopidogrel,
estazolam
insulin.
associated
with
age,
number
diseases
drugs.
shown
be
more
common
patients
aged
70
above,
than
2
kinds
4
Conclusion
this
study.
detection
rate
higher
that
criteria.
Drugs & Aging,
Год журнала:
2022,
Номер
39(3), С. 209 - 221
Опубликована: Фев. 21, 2022
Benefits
and
risks
of
preventive
medication
change
over
time
for
ageing
patients
deprescribing
may
be
needed.
Deprescribing
cardiovascular
antidiabetic
drugs
can
challenging
is
not
widely
implemented
in
daily
practice.The
aim
this
study
was
to
identify
barriers
enablers
cardiometabolic
as
seen
by
healthcare
providers
(HCPs)
different
disciplines,
explore
their
views
on
specific
roles
the
process
deprescribing.Three
focus
groups
with
five
general
practitioners,
eight
pharmacists,
three
nurse
two
geriatricians,
elder
care
physicians
were
conducted
cities
The
Netherlands.
Interviews
recorded
transcribed
verbatim.
Directed
content
analysis
performed
basis
Theoretical
Domains
Framework.
Two
researchers
independently
coded
data.Most
HCPs
agreed
that
relevant
but
include
lack
evidence
expertise,
negative
beliefs
fears,
poor
communication
collaboration
between
HCPs,
resources.
Having
a
guideline
considered
an
enabler
medication.
Some
feared
consequences
discontinuing
or
medication,
while
others
motivated
deprescribe
when
experienced
no
problems
all
disciplines
stated
adequate
patient
involving
relatives
decision
making
enables
deprescribing.
Barriers
included
use
initiated
specialists,
exchange
information,
amount
it
takes
uncertain
about
each
other's
responsibilities.
A
multidisciplinary
approach
including
pharmacist
practitioner
best
way
support
address
related
resources.HCPs
recognized
importance
medical
only
made
close
cooperation
patient.
To
successfully
accomplish
they
strongly
recommended
approach.
Abstract
Background
Considered
the
most
prevalent
noncommunicable
disease
in
childhood,
dental
caries
is
both
an
individual
and
a
collective
burden.
While
international
guidelines
highlight
prevention
as
major
strategy
for
management
children,
health
professionals
still
struggle
to
implement
into
their
clinical
practice.
Further
research
needed
understand
gap
between
theoretical
significance
of
its
lack
implementation
setting.
This
systematic
review
aims
identify
classify
factors
perceived
by
be
barriers
or
facilitators
children.
Method
A
literature
search
was
conducted
three
electronic
databases
(Medline,
Web
Science
Cairn).
Two
researchers
independently
screened
titles,
abstracts
texts.
To
selected,
studies
had
focus
on
children
include
study
participants.
Qualitative
quantitative
were
selected.
The
influencing
sorted
3
main
categories
(clinician-related
factors,
patient-related
organizational-related
factors)
then
classified
according
14
domains
framework
(TDF).
Results
total
1771
references
found
combining
manual
database
searches.
Among
them,
26
met
inclusion
criteria,
which
half
qualitative
studies.
Dentists
(
n
=
12),
pediatricians
11),
nurses
9),
physicians
5)
frequently
interviewed
our
analysis.
Barriers
categorized
12
TDF
domains.
reported
Environmental
Context
Resources
,
Knowledge
Professional
Role
Identity.
Conclusion
that
wide
range
influence
Our
analysis
showed
pediatric
oral
promotion
affect
all
stages
care
system.
By
highlighting
incompatibility
system’s
organization
prevention,
this
help
policy-makers
design
new
interventions
improve
children’s
access
prevention.
Trial
registration
PROSPERO
CRD42022304545.
International Journal of Environmental Research and Public Health,
Год журнала:
2023,
Номер
20(2), С. 1635 - 1635
Опубликована: Янв. 16, 2023
In
Saudi
Arabia,
the
older
adult
population
is
growing
and
projected
to
increase
three-fold
by
2030.
Potentially
inappropriate
medications
(PIMs)
are
harmful
adults'
have
a
direct
impact
on
clinical,
health
economic
outcomes.
Pharmacists
vital
role
in
medication
tailoring
for
adults
as
multidisciplinary
team
members.
However,
there
also
paucity
of
research
regarding
pharmacists'
participation
detecting
avoiding
PIMs
use
among
Arabia.
A
cross-sectional,
self-administered
survey
was
conducted
assess
knowledge,
practices,
attitude
pharmacists
from
seven
hospitals
ten
community
pharmacies
Jeddah,
The
comprised
three
sections;
(i)
identifying
participants'
general
characteristics,
(ii)
assessing
their
knowledge
(iii)
examining
pharmacist's
towards
procedures
followed
dispensing
adults.
Inferential
descriptive
statistics
were
used
analyse
data.
total
157
hospital
participated
this
study.
Most
them
dispensed
weekly
(85.4%),
43.3%
had
relevant
work
experience
six
years.
Though
44.6%
participants
aware
that
should
avoid,
only
10.8%
claimed
adequate
about
PIMs.
From
given
clinical
case
scenarios,
minority
(21.7%)
chose
correct
answers,
with
mean
score
2.38
±
2.91
(95%
CI
2.35-3.15).
Participants
who
significantly
higher
than
those
did
not,
4.59
2.81
25
2.35-2.61).
(14.7%)
screening
tools
such
STOPP,
Beers
criteria,
or
Medication
Appropriateness
Index
(MAI)
detect
No
statistically
significant
differences
detected
when
comparing
levels
1
5
years
practice
6
15
more
(p
=
0.431).
Pharmacists'
practices
toward
Arabia
be
improved.
application
detection
STOPP/START
criteria
currently
has
no
place
day-to-day
roles
Therefore,
concerned
stakeholders
develop
educational
programs
improve
promote
effective
PIM
STOPP
practice.
Journal of the American Geriatrics Society,
Год журнала:
2024,
Номер
72(9), С. 2800 - 2806
Опубликована: Май 6, 2024
Medication
utilization
has
been
increasing
in
the
U.S.
year-over-year
for
several
decades.
As
older
adults
take
more
medications,
there
is
a
higher
risk
of
them
being
exposed
to
drug-drug
or
drug-disease
interactions.
The
American
Geriatrics
Society
2019
updated
their
Beers
Criteria
Potentially
Inappropriate
(PIM)
Use
Older
Adults.
objective
this
study
was
assess
prevalence
medications
included
Criteria.
Frontiers in Pharmacology,
Год журнала:
2022,
Номер
13
Опубликована: Сен. 30, 2022
Objective:
Polypharmacy
increases
the
prevalence
of
potentially
inappropriate
drugs
medications
among
older
persons,
lowering
their
quality
life.
PIMs
use
can
lead
to
higher
mortality
in
patients.
This
study
aimed
compare
Chinese
outpatients
according
Beers
criteria
and
analyze
risk
factors.
Second,
we
describe
differences
between
two
criteria,
focusing
on
prescription
outpatients.
Methods:
In
Chengdu,
Southwest
China,
a
cross-sectional
was
undertaken
using
electronic
medical
data
from
9
general
hospitals
s.
Outpatients
above
age
60
who
were
treated
Geriatrics
Center
these
institutions
included.
The
2019
2017
used
evaluate
PIM
status
outpatients,
binary
logistic
regression
identify
potential
factors
for
PIMs.
Results:
There
44,458
prescriptions
2016
2018.
30.05%
(according
criteria)
35.38%
criteria),
with
statistical
difference.
Estazolam,
hydrochlorothiazide
alprazolam
top
three
while
clopidogrel,
estazolam
insulin.
associated
age,
number
diseases
drugs.
shown
be
more
common
patients
aged
70
above,
than
2
kinds
4
Conclusion:
this
study.
detection
rate
that
criteria.
Research in Social and Administrative Pharmacy,
Год журнала:
2023,
Номер
19(10), С. 1372 - 1379
Опубликована: Июнь 17, 2023
Certain
medications
should
be
used
with
caution
in
older
persons,
which
challenges
rational
prescribing.
Potentially
inappropriate
(PIMs)
are
defined
as
medicines
whose
potential
risk
of
harm
typically
outweighs
the
clinical
benefits
geriatric
population.
Earlier
studies
have
found
regional
differences
PIM
use,
but
factors
underlying
this
phenomenon
unclear.To
compare
prescription
prevalence
among
Finnish
hospital
districts
and
determine
population
characteristics
related
to
social
health
care
associated
variation.This
nationwide
register
study
was
based
on
Prescription
Centre
data
all
people
aged
≥75
years
2017-2019.
Hospital
district
(n
=
20)
were
drawn
from
Institute
for
Health
Welfare's,
Medical
Association's,
Medicines
Agency's
publicly
open
data.
PIMs
according
Meds75+
database.
A
linear
mixed-effect
model
analyze
associations
prevalence.Prevalence
varied
between
16.4%
24.8%
across
regions.
The
highest
observed
southern
regions,
while
lowest
west
coast.
higher
share
living
alone,
excessive
polypharmacy,
or
assessed
using
Resident
Assessment
Instrument,
shortage
general
practitioners
municipal
centers,
low
home
personnel.
Waiting
time
morbidities
not
use.
Of
total
variance
prevalence,
86%
explained
by
group-level
districts.
variables
75%
hospital-district-level
variation.PIM
significantly
Findings
suggest
that
may
continuity
rather
than
accessibility
morbidities.
Aging Medicine,
Год журнала:
2021,
Номер
4(3), С. 180 - 192
Опубликована: Июль 20, 2021
Abstract
Objectives
We
aimed
to
understand
the
barriers
experienced
by
physicians
when
prescribing
for
older
adults
with
multimorbidity
in
specialist
outpatient
clinics
Singapore.
Methods
A
modified
Delphi
study
was
conducted
via
email
20
panel
experts
field
of
geriatric
medicine.
Barriers
identified
from
an
earlier
scoping
review
were
presented
as
statements
panel.
Results
Eleven
barrier
reached
consensus
high
importance
according
Of
these
statements,
seven
(64%)
belong
domain
Environmental
context
and
resources
Theoretical
Domains
Framework
(TDF),
while
remaining
domains
skills,
knowledge,
intentions,
professional/social
role
identity
.
The
are
further
linked
intervention
functions
Behaviour
Change
Wheel
(BCW).
Conclusion
Linking
TDF
revealed
strategic
directions
development
address
optimize
prescribing.
