Anticholinergic drug exposure is associated with prevalence, worsening and incidence of dysphagia among hospitalized older adults
The journal of nutrition health & aging,
Год журнала:
2025,
Номер
29(5), С. 100507 - 100507
Опубликована: Фев. 13, 2025
Язык: Английский
The prevalence and evolution of binary multimorbidity pattern in middle-aged and elderly population in China, from an insight of health metrics
Data Science and Informetrics,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 1, 2025
Язык: Английский
An analysis of protective health behavior and polypharmacy among older patients: a nationwide cohort study
BMC Geriatrics,
Год журнала:
2024,
Номер
24(1)
Опубликована: Июль 30, 2024
Abstract
Background
This
study
analyzed
the
relationship
between
protective
health
behaviors
and
polypharmacy
in
individuals
aged
65
years
older.
Methods
We
used
data
from
a
nationwide
survey
(KNHANES)
2012
to
2016
conjunction
with
insurance
claims
databases.
A
total
of
3297
adults
or
older
were
included
study.
Polypharmacy
was
defined
as
more
than
30
prescription
days
6
months
five
different
drugs.
Health-related
(BMI,
smoking,
drinking,
regular
walking,
living
alone)
extracted
for
before
measuring
polypharmacy.
multivariable
logistic
regression
on
each
behavior,
well
composite
score
behavior.
Subgroup
analysis
also
conducted
by
age
sex.
Results
Among
behaviors,
BMI
<
25
(OR,
0.76;
95%
CI,
0.66–0.88)
never
smoking
0.78;
0.62–0.98)
associated
lower
risk
significantly
both
sex
subgroups
(male:
OR,
0.71;
0.56–0.88;
female:
0.81;
0.67–0.99)
65–79
subgroup
0.74;
0.63–0.86).
The
association
only
significant
0.55–0.91).
Participants
had
participants
zero
one
which
statistically
0.52;
0.29–0.94).
Conclusions
finds
that
such
obesity
are
higher
Furthermore,
we
confirm
high
is
Our
findings
indicate
need
geriatric-centered
management
prevent
Язык: Английский
Association between polypharmacy and 2-year outcomes among Chinese older inpatients: a multi-center cohort study
BMC Geriatrics,
Год журнала:
2024,
Номер
24(1)
Опубликована: Сен. 9, 2024
Язык: Английский
Risk factors correlated to potentially inappropriate medications in the elderly
Research Square (Research Square),
Год журнала:
2024,
Номер
unknown
Опубликована: Апрель 3, 2024
Abstract
Backgroud
The
prevalence
of
multimorbidity
(
≥2
chronic
disorders
in
the
same
individual),
polypharmacy
≥5
medications
individual)
and
potentially
inappropriate
(PIMs)
elderly
patients
was
very
high.
Methods
This
is
a
cross-sectional
analysis
276
aged
≥65
years
old.
PIMs
analyzed
based
on
Beers
criteria
(2019
edition)
Chinese
criteria,
were
divided
into
non-PIMs,
1PIMs
group
both
critieria.
Logistic
regression
wasconducted
to
investigate
factors
related
PIMs.
Results
as
high
96.74%
(n=267).
91.30%
(n=252)
had
polypharmacy.
Determined
by
40.22%
(n=111)
41.30%
(n=114)
1
PIMs,
26.09%
(n=72)
13.77%
(n=38)
2
or
more
Based
with
prescribed
compared
non-PIMs
(median
[inter-quartile
range,
IQR]:
10[7–12]
vs.7[5-9]),
significant
(11[9.25-13]
vs
8[7-11]);
Similar
results
found
criteria.
Further
logistic
showed
that
strongest
predictor
increased
number
determined
(P<0.001).
Gender,
diseases
age
not
risk
factor
correlated
our
study.
Conclusion
common,
Язык: Английский
Structured medication reviews for adults with multimorbidity and polypharmacy in primary care: a systematic review protocol
BMJ Open,
Год журнала:
2024,
Номер
14(5), С. e082825 - e082825
Опубликована: Май 1, 2024
Introduction
Polypharmacy
is
common
among
individuals
with
multimorbidity,
often
leading
to
inappropriate
medication
use
and
associated
an
increased
risk
of
frailty,
hospitalisation
mortality.
Structured
reviews
(SMRs)
have
emerged
as
a
promising
method
for
optimising
use.
However,
research
examining
their
efficacy
limited.
This
review
aims
evaluate
the
impact
SMRs
on
improving
outcomes
adults
multimorbidity
polypharmacy
in
primary
care
settings.
Additionally,
this
seeks
identify
prevailing
patterns
trends
mode
delivery
SMRs.
Methods
analysis
A
systematic
will
be
conducted
using
Ovid
MEDLINE,
EMBASE,
Web
Science
CINAHL
(1997–present).
Primary
include
medication-related
measures
such
dose,
frequency
dosage
form.
Secondary
under
investigation
physical,
mental,
functional
health
service
outcomes,
reported.
Two
independent
reviewers
conduct
screening
data
extraction,
resolving
disagreements
through
discussion.
Once
eligible
studies
are
identified,
extracted
summarised
tabular
format.
The
bias
articles
assessed
either
Cochrane
Risk
Bias
2
tool
or
Newcastle-Ottawa
scale,
depending
design
retrieved.
Subgroup
performed
demographic
variables
modes
where
supports.
If
appropriate,
meta-analysis
determine
reported
outcomes.
not
possible
due
heterogeneity,
narrative
synthesis
approach
adopted.
Ethics
dissemination
proposed
exempt
from
ethical
approval
it
collate
summarise
peer-reviewed,
published
evidence.
protocol
subsequent
disseminated
peer-reviewed
journals,
conferences
patient-led
lay
summaries.
PROSPERO
registration
number
CRD42023454965.
Язык: Английский
PREVALÊNCIA DA POLIFARMÁCIA ASSOCIADA A FUNCIONALIDADE EM PESSOAS IDOSAS HOSPITALIZADAS
Revista Enfermagem Atual In Derme,
Год журнала:
2024,
Номер
98(3), С. e024347 - e024347
Опубликована: Июль 1, 2024
As
Doenças
Crônicas
não
Transmissíveis
são
uma
crescente
na
população
idosa.
Essas,
dentre
outras
causas,
desencadeiam
um
aumento
no
consumo
de
medicamentos,
levando
a
polifarmácia.
Objetivo:
Analisar
prevalência
da
polifarmácia
associada
funcionalidade
em
pessoas
idosas
hospitalizadas.
Metodologia:
Estudo
transversal,
quantitativo,
realizado
com
indivíduos
hospitalizados
60
anos
ou
mais
(n=673).
Foi
realizada
coleta
dados
à
beira
leito,
utilizando
o
instrumento
validado
Índice
Vulnerabilidade
Clínico-Funcional.
Empregou-se
como
variável
dependente
uso
concomitante
cinco
medicamentos
(polifarmácia)
e
as
variáveis
independentes
foram
questões
relacionadas
características
funcionais
–
autopercepção
saúde,
esquecimento
relatado
por
familiar,
piorado
nos
últimos
meses,
dificuldade
para
caminhar,
quedas
último
ano
incontinência
esfincteriana.
Realizou-se
teste
qui-quadrado
regressão
logística.
Resultados:
A
foi
28%
esteve
deixar
tomar
banho
sozinho
(OR=1,70;IC95%=1,16-2,50;p=0,007),
esfincteriana
(OR=2,08;IC95%=1,41-3,07;p<0,001)
meses
(OR=1,97;
IC95%=1,33-2,93;
p=0,001).
Conclusão:
Verificou-se
alta
nas
hospitalizadas,
sendo
que
esta
condição
atrelada
ao
ato
sozinho,
indício
comprometimento
cognitivo.
Association between reproductive lifespan and multimorbidity among Chinese postmenopausal women
Menopause The Journal of The North American Menopause Society,
Год журнала:
2024,
Номер
31(11), С. 945 - 951
Опубликована: Июль 30, 2024
Although
menopause
is
considered
a
risk
factor
for
multimorbidity,
few
studies
have
explored
the
association
between
reproductive
lifespan
and
multimorbidity.
This
study
aimed
to
explore
multimorbidity
in
postmenopausal
Chinese
women.
Язык: Английский
Changes in patterns of multimorbidity and associated with medical costs among Chinese middle-aged and older adults from 2013 to 2023: an analysis of repeated cross-sectional surveys in Xiangyang, China
Changyu Ju,
Hongjia Liu,
Yongxiang Gong
и другие.
Frontiers in Public Health,
Год журнала:
2024,
Номер
12
Опубликована: Авг. 7, 2024
Background
Multimorbidity
has
become
a
major
public
health
problem
among
Chinese
middle-aged
and
older
adults,
the
most
costly
to
care
system.
However,
previous
population-based
studies
of
multimorbidity
have
focused
on
limited
number
chronic
diseases,
diagnosis
was
based
participants’
self-report,
which
may
oversimplify
problem.
At
same
time,
there
were
few
reports
relationship
between
patterns
costs.
This
study
analyzed
changes
people
in
China
over
past
decade,
their
association
with
medical
costs,
representative
hospital
electronic
record
data.
Methods
Two
cross-sectional
surveys
data
used
obtain
adults
aged
45
years
Xiangyang
2013
(
n
=
20,218)
2023
63,517).
Latent
Class
Analysis
analyze
multimorbidity,
gray
correlation
analysis
ordered
logistics
model
assess
expenses.
The
classification
diseases
International
Classification
Diseases,
Tenth
Revision
codes
(ICD-10).
Results
detection
rate
disease
increased
(70.74
vs.
76.63%,
p
<
0.001),
from
6
9
(2013:
Malignant
tumors
pattern,
non-specific
ischemic
heart
+
hypertension
cerebral
infarction
kidney
lens
pattern;
new
2023:
Nutritional
metabolism
disorders
lower
respiratory
malignant
gastrointestinal
pattern)
China.
cost
all
patients
been
reduced
(RMB:
8216.74
7247.96,
IQR:
5802.28–15,737
5014.63–15434.06).
top
three
specific
both
malignancy
tumor
pattern.
Hypertension
type
2
diabetes
are
important
components
patterns.
Compared
single
disease,
only
pattern
at
risk
higher
costs
(aOR:1.23,
95%
CI:
1.03,
1.47),
whereas
significantly
associated
2023,
except
for
(aOR:0.35,
0.32,
0.39).
Moreover,
odds
not
consistent
across
Among
them,
[adjusted
ratio
(aOR):4.66,
95%CI:
4.31,
5.05]
(aOR:
3.63,
3.35,
3.92)
two
highest
risk.
Meanwhile,
men
(aOR:1.12,
95CI:1.09,
1.16),
no
spouse
(aOR:1.09,
95CI:
1.16)
had
positive
effect
while
total
self-pay
0.45,
0.29,
0.70),
surgery
0.05,
0.05),
rural
residence
0.92,
0.89,
0.95),
hospitalization
days
1–5
0.04,
0.04),
6–9
0.15,
0.16)
negative
impact
Conclusion
diversified
decade
rising
Smart,
decisive
comprehensive
policy
interventions
needed
effectively
manage
NCDS
factors
reduce
economic
burden
country.
Язык: Английский
Ethical and Legal Challenges in Caring for Older Adults with Multimorbidities: Best Practices for Nurses
Healthcare,
Год журнала:
2024,
Номер
12(16), С. 1585 - 1585
Опубликована: Авг. 9, 2024
This
study
explores
the
ethical
and
legal
challenges
faced
by
nurses
in
caring
for
older
adults
with
multimorbidities,
focusing
on
issues
related
to
patient
autonomy,
polypharmacy,
end-of-life
care.
Through
semi-structured
interviews
15
Riyadh,
Saudi
Arabia,
research
highlights
complexities
of
obtaining
informed
consent
from
patients
cognitive
impairments
dilemmas
balancing
autonomy
safety.
The
management
polypharmacy
emerged
as
a
significant
concern,
emphasizing
importance
thorough
documentation
coordination
among
healthcare
providers
prevent
adverse
drug
interactions.
End-of-life
care
advance
directives
posed
further
challenges,
particularly
when
family
members
disagreed
patients’
documented
wishes.
underscores
need
comprehensive
strategies,
including
ongoing
education,
clear
communication,
supportive
institutional
policies,
address
these
effectively.
findings
suggest
that
enhancing
nurses’
understanding
principles
requirements
is
crucial
improving
ensuring
compliance
regulatory
standards.
Future
should
aim
develop
evidence-based
guidelines
support
nursing
practice
managing
challenges.
Язык: Английский