Advanced synthesis and biomedical applications of colloidal quantum dots: Innovations in Imaging, drug delivery, and theranostics

Inorganic Chemistry Communications, Год журнала: 2025, Номер unknown, С. 114533 - 114533

Опубликована: Апрель 1, 2025

Язык: Английский

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Epigenomic insights and computational advances in hematologic malignancies

Molecular Cytogenetics, Год журнала: 2025, Номер 18(1)

Опубликована: Апрель 12, 2025

Hematologic malignancies (HMs) encompass a diverse spectrum of cancers originating from the blood, bone marrow, and lymphatic systems, with myeloid representing significant complex subset. This review provides focused analysis their classification, prevalence, incidence, highlighting persistent challenges posed by intricate genetic epigenetic landscapes in clinical diagnostics therapeutics. The basis malignancies, including chromosomal translocations, somatic mutations, copy number variations, is examined detail, alongside modifications specific emphasis on DNA methylation. We explore dynamic interplay between factors, demonstrating how these mechanisms collectively shape disease progression, therapeutic resistance, outcomes. Advances diagnostic modalities, particularly those integrating epigenomic insights, are revolutionizing precision diagnosis HMs. Key approaches such as nano-based contrast agents, optical imaging, flow cytometry, circulating tumor analysis, mutation testing discussed, particular attention to transformative role machine learning data analysis. methylation episignatures have emerged pivotal tool, enabling development highly sensitive prognostic assays that now being adopted practice. also impact computational advancements integration refining strategies. By combining genomic profiling techniques, innovations accelerating biomarker discovery translation, applications oncology becoming increasingly evident. Comprehensive datasets, coupled artificial intelligence, driving actionable insights into biology facilitating optimization patient management Finally, this emphasizes translational potential advancements, focusing tangible benefits for care synthesizing current knowledge recent innovations, we underscore critical medicine research transforming treatment setting stage ongoing broader implementation.

Язык: Английский

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Core-Shell Hybrid Liposomes: Transforming Imaging Diagnostics and Therapeutic Strategies

Colloids and Surfaces B Biointerfaces, Год журнала: 2025, Номер unknown, С. 114597 - 114597

Опубликована: Фев. 1, 2025

Язык: Английский

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Recent advances in DNA nanotechnology for cancer detection and therapy: A review

International Journal of Biological Macromolecules, Год журнала: 2025, Номер unknown, С. 142136 - 142136

Опубликована: Март 1, 2025

Язык: Английский

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