Recent advances in DNA nanotechnology for cancer detection and therapy: A review DOI

Donya Esmaeilpour,

Matineh Ghomi, Ehsan Nazarzadeh Zare‬

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 142136 - 142136

Published: March 1, 2025

Language: Английский

Advanced synthesis and biomedical applications of colloidal quantum dots: Innovations in Imaging, drug delivery, and theranostics DOI
F. S. Razavi, Zahra Razavi,

Haniyeh Shahsavari

et al.

Inorganic Chemistry Communications, Journal Year: 2025, Volume and Issue: unknown, P. 114533 - 114533

Published: April 1, 2025

Language: Английский

Citations

0
Epigenomic insights and computational advances in hematologic malignancies DOI Creative Commons

Carolyn Lauzon-Young,

Ananilia Silva,

Bekim Sadiković

et al.

Molecular Cytogenetics, Journal Year: 2025, Volume and Issue: 18(1)

Published: April 12, 2025

Hematologic malignancies (HMs) encompass a diverse spectrum of cancers originating from the blood, bone marrow, and lymphatic systems, with myeloid representing significant complex subset. This review provides focused analysis their classification, prevalence, incidence, highlighting persistent challenges posed by intricate genetic epigenetic landscapes in clinical diagnostics therapeutics. The basis malignancies, including chromosomal translocations, somatic mutations, copy number variations, is examined detail, alongside modifications specific emphasis on DNA methylation. We explore dynamic interplay between factors, demonstrating how these mechanisms collectively shape disease progression, therapeutic resistance, outcomes. Advances diagnostic modalities, particularly those integrating epigenomic insights, are revolutionizing precision diagnosis HMs. Key approaches such as nano-based contrast agents, optical imaging, flow cytometry, circulating tumor analysis, mutation testing discussed, particular attention to transformative role machine learning data analysis. methylation episignatures have emerged pivotal tool, enabling development highly sensitive prognostic assays that now being adopted practice. also impact computational advancements integration refining strategies. By combining genomic profiling techniques, innovations accelerating biomarker discovery translation, applications oncology becoming increasingly evident. Comprehensive datasets, coupled artificial intelligence, driving actionable insights into biology facilitating optimization patient management Finally, this emphasizes translational potential advancements, focusing tangible benefits for care synthesizing current knowledge recent innovations, we underscore critical medicine research transforming treatment setting stage ongoing broader implementation.

Language: Английский

Citations

0
Core-Shell Hybrid Liposomes: Transforming Imaging Diagnostics and Therapeutic Strategies DOI Creative Commons
Joana Cunha, Eloah Latocheski,

Ana Fidalgo

et al.

Colloids and Surfaces B Biointerfaces, Journal Year: 2025, Volume and Issue: unknown, P. 114597 - 114597

Published: Feb. 1, 2025

Language: Английский

Citations

0
Recent advances in DNA nanotechnology for cancer detection and therapy: A review DOI

Donya Esmaeilpour,

Matineh Ghomi, Ehsan Nazarzadeh Zare‬

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 142136 - 142136

Published: March 1, 2025

Language: Английский

Citations

0