Pharmaceutical and Hydrogel Applications of Marine Collagen DOI
Abhilash Sasidharan

Опубликована: Янв. 1, 2024

The collagen derived from marine sources such as scales and bones of fishes has achieved focus in pharmaceutical industry. Its recent innovation a biocompatible hydrogel raw material also enhanced the interest among researchers particular fields due to their specific characteristics. industry utilizes drug delivery tool, with capability promote controlled release excellent bioavailability properties. biocompatibility lower risk immunogenicity qualify an ideal choice for healing wounds, engineering tissue including regenerative medicinal functions. In application hydrogel, it exhibits crucial characteristics by assisting establishing matrix that simulate extracellular conditions. Such hydrogels are applied systems capacity sustained therapeutic drugs. Furthermore, innate bioactivity advocates cell connection propagation, which fundamental repair. versatile nature, paired its availability environment, emphasizes prospective enhancing preparations hydrogel-based technologies, aiding develop novel solutions biotechnology medicine. This chapter discusses applications isolated resources.

Язык: Английский

Chitosan: An overview of biological activities, derivatives, properties, and current advancements in biomedical applications DOI
Great Iruoghene Edo, Emad͏͏͏͏͏͏͏͏͏͏͏͏͏͏͏͏͏͏͏ Yousif, Mohammed H. Al‐Mashhadani

и другие.

Carbohydrate Research, Год журнала: 2024, Номер 542, С. 109199 - 109199

Опубликована: Июнь 27, 2024

Язык: Английский

Процитировано

38

Biomaterials for inflammatory bowel disease: treatment, diagnosis and organoids DOI
Jia Wang, Yuying Shi,

Bei Mao

и другие.

Applied Materials Today, Год журнала: 2024, Номер 36, С. 102078 - 102078

Опубликована: Янв. 20, 2024

Язык: Английский

Процитировано

9

Strong and tough chitin hydrogel constructed by dehydration and rehydration strategy DOI
Ruirui Liu, Li‐Bo Mao, Shu‐Hong Yu

и другие.

Nano Research, Год журнала: 2024, Номер 17(9), С. 8192 - 8199

Опубликована: Июнь 24, 2024

Язык: Английский

Процитировано

4

Therapeutic Potential of Plant- and Marine-Derived Bioactive Compounds in Prostate Cancer: Mechanistic Insights and Translational Applications DOI Creative Commons
Arif Jamal Siddiqui, Mohd Adnan, Juhi Saxena

и другие.

Pharmaceuticals, Год журнала: 2025, Номер 18(3), С. 286 - 286

Опубликована: Фев. 20, 2025

It is widely recognized that prostate cancer a multifaceted illness the second most common cause of cancer-related fatalities among males. Natural sources from both plants and marine organisms have long been used in treating various diseases discovery new pharmaceutical compounds. Medicinal plants, particular, provide bioactive substances like alkaloids, phenolic compounds, terpenes, steroids. In addition, natural products play crucial role search for novel treatments. A substantial number anticancer drugs derived sources, including organisms, microorganisms. fact, over past 60 years, 80% chemical entities originated which are generally considered safer than synthetic This review seeks to emphasize phytochemical compounds plant cancer, highlighting their potential therapeutic impact. also intended support global researchers working on identification natural-based treatments cancer.

Язык: Английский

Процитировано

0

Exploring sulphated polysaccharides from marine bivalves: Unveiling potent anti-gastric cancer activity through cell cycle arrest and apoptosis DOI
Deepakrajasekar Padmanaban,

P. R. Kannan Rajkumar,

M. Vijayakumar

и другие.

Journal of Asian Natural Products Research, Год журнала: 2025, Номер unknown, С. 1 - 22

Опубликована: Фев. 22, 2025

This study investigates the extraction of partially purified sulphated polysaccharides from marine bivalves through enzymatic digestion followed by sequential deproteinization and evaluates their anti-gastric cancer activity. Chemical analysis confirmed high uronic acid sulfate content, with FT-IR validating characteristic functional groups. Donax variabilis polysaccharide demonstrated significant, dose-dependent anti-proliferative effects against AGS cells. Mechanistic studies revealed morphological changes, ROS generation, LDH release, mitochondrial membrane disruption, leading to apoptosis. Flow cytometry G0/G1 phase arrest. These findings suggest that D. exhibit potent properties, likely oxidative stress dysfunction, warranting further investigation for therapeutic applications.

Язык: Английский

Процитировано

0

Innovation in Osteogenesis Activation: Role of Marine-Derived Materials in Bone Regeneration DOI Creative Commons
Maria Giovanna Rizzo, Marilena Briglia, Vincenzo Zammuto

и другие.

Current Issues in Molecular Biology, Год журнала: 2025, Номер 47(3), С. 175 - 175

Опубликована: Март 7, 2025

Marine-derived biomaterials are emerging as promising candidates for tissue regeneration due to their sustainability, biocompatibility, bioactivity, and unique chemical structure. This review provides an overview of different marine-derived inorganic organic materials, such calcium carbonate, magnesium salts, silica, polysaccharides, bioactive peptides, lipid-based compounds, effects in promoting osteogenesis. Specifically, the osteoinductive, osteoconductive, osteointegrative activities traditional innovative materials that influence key molecular pathways BMP/Smad Wnt/β-catenin signaling underlying bone formation will be evaluated. also prospects approaches, i.e., phage display technology, optimize peptides targeted regeneration. In context sustainable this suggests some interesting applications unusual able overcome limitations conventional ones stimulate cellular by activating specific pathways.

Язык: Английский

Процитировано

0

Comprehensive Review on Application Progress of Marine Collagen Cross-Linking Modification in Bone Repairs DOI Creative Commons
Xiaofei Zhai,

X. Geng,

Wenjun Li

и другие.

Marine Drugs, Год журнала: 2025, Номер 23(4), С. 151 - 151

Опубликована: Март 30, 2025

Bone tissue injuries are a significant health risk, and their repair is challenging. While various materials have potential for bone repair, issues like sourcing immune rejection limit use. Marine-derived collagen, abundant free from religious disease transmission concerns, promising biomaterial in engineering. Cross-linking modification can enhance its mechanical properties degradation rate, making it more suitable repair. However, detailed analysis of cross-linking methods, property changes post-cross-linking, impact on needed. This review examines marine collagen’s improved characteristics, providing foundation effective use

Язык: Английский

Процитировано

0

Nanoarchitectonics of catalytic tubular nanomotors based on Cu/Fe@SBA-15 for lung cancer treatment DOI Creative Commons
Mohamed S. El-Okaily, Ahmed M. A. El‐Seidy,

Eman H. Ismail

и другие.

Journal of materials research/Pratt's guide to venture capital sources, Год журнала: 2024, Номер 39(12), С. 1741 - 1757

Опубликована: Апрель 30, 2024

Abstract Fabrications of nanomotors (NMs) are at the forefront exploring true potential nanotechnology. Tubular (TNMs) have been attracting huge interest recently. NMs based on 2D-hexagonal mesoporous silica (SBA-15) prepared through surfactant-assisted sol–gel method. Copper and/or iron oxide nanoparticles impregnated in SBA-15 to form catalytic tubular nanomotors. Characterization has investigated by XPS, XRD, HR-TEM, SEM–EDS, and BET. The electrochemical measurements were used confirm motion By increasing loading metal nanoparticles, decreases; this could be observed from current loss. anti-cancer synthesized against two cell lines (A549 H460) human lung carcinoma tested. Among all tested NMs, high-metal oxide-loaded materials containing CuO only as well Fe 2 O 3 potent significant apoptotic death for cancer treatment. Graphical abstract

Язык: Английский

Процитировано

3

Innovative Marine‐Sourced Hydroxyapatite, Chitosan, Collagen, and Gelatin for Eco‐Friendly Bone and Cartilage Regeneration DOI
Hoda Elkhenany, Mariam Waleed Soliman, Diaa Atta

и другие.

Journal of Biomedical Materials Research Part A, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 7, 2024

In recent years, the exploration of sustainable alternatives in field bone tissue engineering has led researchers to focus on marine waste byproducts as a valuable resource. These resources, often overlooked remnants various industries, exhibit rich composition hydroxyapatite, collagen, calcium carbonate, and other minerals essential complex framework structure. Marine by-products can emit gases such methane carbon dioxide, highlighting urgency repurpose these materials for innovative regeneration solutions, offering approach address environmental challenges while advancing medical science. Using discarded offers promising pathway development regenerative medicine. This review investigates distinctive properties byproducts, emphasizing their capacity be recycled effectively contribute rebuilding cartilage during processes. We also highlight compatibility resources with biological platelet-rich plasma (PRP), stem cells, exosomes, natural bioproducts, well nanoparticles (NPs) polymers. By using potential we simultaneously promote solutions skeletal engineering, initiating new era environmentally green biomedical research.

Язык: Английский

Процитировано

2

On the Potential of Optical Nanoantennas for Visibly Transparent Solar Cells DOI Creative Commons
Wayesh Qarony, Mohammad Ismail Hossain, Asman Tamang

и другие.

ACS Photonics, Год журнала: 2023, Номер 10(12), С. 4205 - 4214

Опубликована: Ноя. 28, 2023

This study aims to determine the maximum possible energy conversion efficiency of visibly transparent solar cells using detailed balance limit (also known as Shockley–Queisser limit) and compare it traditional single-junction cells. To achieve this, a new optical nanoantenna has been designed absorb incoming light selectively, enhancing average visible transmission while maintaining high absorption in infrared UV regions. The color appearance antennas also evaluated through colorimetrical characterization. Our findings indicate that is transparency over 80 18%, respectively, by carefully selecting semiconductor materials. Such are versatile enough be integrated seamlessly into smart windows, agrivoltaic concepts open protected cultivation, mobile devices, appliances without compromising their or functionality. dimensions optics proposed have thoroughly discussed.

Язык: Английский

Процитировано

5