Korean Journal of Otorhinolaryngology - Head and Neck Surgery, Год журнала: 2024, Номер unknown
Опубликована: Ноя. 14, 2024
Materials & Design, Год журнала: 2024, Номер 241, С. 112886 - 112886
Опубликована: Март 28, 2024
The rising incidence of defects in oral and maxillofacial tissues, linked to factors such as trauma, tumors, periodontal disease, aging, poses significant challenges. Current treatments, involving autografts, allografts, synthetic graft materials, face obstacles like secondary inflammation, inadequate biocompatibility. Tissue engineering, integrating cell biology material science since the 1990s, relies heavily on biomaterial scaffolds promote adhesion, proliferation, differentiation. Traditional scaffold fabrication, including 3D printing, methods lack precision, hindering effective tissue repair by controlling distribution extracellular matrix. Biomedical engineering advancements have introduced bioprinting an innovative solution, overcoming constraints conventional scaffolds. technology enables rapid precise reconstruction damaged tissues with loaded cells, mimicking vivo environments. This paper explores key technologies inkjet-based, extrusion-based, fused deposition modeling, laser-assisted, VAT photopolymerization, freeform reversible embedding suspended hydrogels, sacrificial template printing. selection materials suitable mechanical biological properties is crucial, considering distinct requirements each technique. review provides a comprehensive survey research progress printing applications craniofacial dental serving valuable reference for future medical research.
Язык: Английский
Процитировано
21
Bioactive Materials, Год журнала: 2024, Номер 35, С. 306 - 329
Опубликована: Фев. 10, 2024
To examine the 16-year developmental history, research hotspots, and emerging trends of zinc-based biodegradable metallic materials from perspective structural temporal dynamics. The literature on in WoSCC was searched. Historical characteristics, evolution active topics development field were analyzed using bibliometric tools CiteSpace HistCite. Over past 16 years, metal has remained a hotspot stage, with extensive scientific collaboration. In addition, there are 45 subject categories 51 keywords different periods, 80 papers experience citation bursts. Keyword clustering anchored 3 subfields, namely, #1 plastic deformation #4 additive manufacturing #5 surface modification. keyword alluvial map shows that longest-lasting concepts mechanical property, microstructure, corrosion behavior, etc., manufacturing, modification, dynamic recrystallization, etc. most recent reference six subfields. Namely, #0 #2 sem, #3 laser powder bed fusion, implant, #7 Zn–1Mg. results study provide current status materials, which can help researchers identify hot spots explore new directions field.
Язык: Английский
Процитировано
19
Advances in healthcare information systems and administration book series, Год журнала: 2024, Номер unknown, С. 132 - 152
Опубликована: Фев. 14, 2024
Among the various manufacturing processes currently in use by industry, 3D printing stands out as a unique additive technique. It enables creation of three-dimensional solid objects virtually any shape from digital model. Initially considered an ambitious concept, medical has become reality thanks to substantial time and investment. This chapter delves into recent advancements within modern field, offering concise overview how why is transforming practices, education, research. serves introduction subject, followed demonstration state-of-the-art through industry developments. The significance this lies its comprehensive coverage evolving role healthcare, highlighting not only current applications challenges but also underscoring potential revolutionize aspects science patient care.
Язык: Английский
Процитировано
18
Surfaces and Interfaces, Год журнала: 2025, Номер unknown, С. 105735 - 105735
Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
2
Journal of Functional Biomaterials, Год журнала: 2024, Номер 15(10), С. 280 - 280
Опубликована: Сен. 25, 2024
Bone tissue regeneration is a rapidly evolving field aimed at the development of biocompatible materials and devices, such as scaffolds, to treat diseased damaged osseous tissue. Functional scaffolds maintain structural integrity provide mechanical support defect site during healing process, while simultaneously enabling or improving through amplified cellular cues between scaffold native tissues. Ample research on functionalization has been conducted improve scaffold–host interaction, including fabrication techniques, biomaterial selection, surface modifications, integration bioactive molecular additives, post-processing modifications. Each these methods plays crucial role in not only but actively participate process bone joint surgery. This review provides state-of-the-art, comprehensive overview scaffold-based strategies used engineering, specifically for regeneration. Critical issues obstacles are highlighted, applications advances described, future directions identified.
Язык: Английский
Процитировано
14
Exploration of Medicine, Год журнала: 2024, Номер 5(1), С. 17 - 47
Опубликована: Фев. 6, 2024
Three-dimensional (3D) and four-dimensional (4D) printing have emerged as the next-generation fabrication technologies, covering a broad spectrum of areas, including construction, medicine, transportation, textiles. 3D printing, also known additive manufacturing (AM), allows complex structures with high precision via layer-by-layer addition various materials. On other hand, 4D technology enables smart materials that can alter their shape, properties, functions upon stimulus, such solvent, radiation, heat, pH, magnetism, current, pressure, relative humidity (RH). Myriad biomedical (BMMs) currently serve in many engineering fields aiding patients’ needs expanding life-span. BMMs provides geometries are impossible conventional processing techniques, while yields dynamic BMMs, which intended to be long-term contact biological systems owing time-dependent stimuli responsiveness. This review comprehensively covers most recent technological advances towards fabricating for tissue engineering, drug delivery, surgical diagnostic tools, implants prosthetics. In addition, challenges gaps printed along future outlook, extensively discussed. The current addresses scarcity literature on composition, performances medical applications pros cons. Moreover, content presented would immensely beneficial material scientists, chemists, engineers engaged AM clinicians field. Graphical abstract.
Язык: Английский
Процитировано
10
Biofabrication, Год журнала: 2024, Номер 16(2), С. 022007 - 022007
Опубликована: Март 20, 2024
Abstract The application of additive manufacturing (AM) technology plays a significant role in various fields, incorporating wide range cutting-edge technologies such as aerospace, medical treatment, electronic information, and materials. It is currently widely adopted for services, national defense, industrial manufacturing. In recent years, AM has also been extensively employed to produce bone scaffolds implant Through AM, products can be manufactured without being constrained by complex internal structures. particularly advantageous the production macroscopically irregular microscopically porous biomimetic scaffolds, with short cycles required. this paper, commonly used orthopedic implants overviewed analyze different materials structures AM. applications antibacterial biologically relevant animal models are discussed. Also, influence on comprehensive performance product mechanics, mass transfer, biology explored. By identifying reasons limited existing biomedical field, solutions proposed. This study provides an important reference future development field healthcare. conclusion, technologies, requirements building bridges between biomaterials, additives, tissue engineering described highlighted. Nevertheless, more caution should exercised when designing conducting vivo trials, due lack standardized processes, which prevents accuracy results reduces reliability information.
Язык: Английский
Процитировано
9
Materials Today Bio, Год журнала: 2025, Номер 31, С. 101531 - 101531
Опубликована: Фев. 5, 2025
Three-dimensional (3D) printing technology has shown significant promise in the medical field, particularly orthopedics, prosthetics, tissue engineering, and pharmaceutical preparations. This review focuses on innovative application of 3D addressing challenges osteonecrosis femoral head (ONFH). Unlike traditional hip replacement surgery, which is often suboptimal for younger patients, offers precise localization necrotic areas ability to create personalized implants. By integrating advanced biomaterials, this a promising strategy approach early hip-preserving treatments. Additionally, 3D-printed bone engineering scaffolds can mimic natural environment, promoting regeneration vascularization. In future, potential extends combining with artificial intelligence optimizing treatment plans, developing materials enhanced bioactivity compatibility, translating these innovations from laboratory clinical practice. demonstrates how uniquely addresses critical ONFH treatment, including insufficient vascularization, poor mechanical stability, limited long-term success conventional therapies. introducing gradient porous scaffolds, bioactive material coatings, AI-assisted design, work outlines novel strategies improve interventions. These advancements not only enhance efficacy but also pave way findings into applications.
Язык: Английский
Процитировано
1
Medicinski Glasnik, Год журнала: 2025, Номер 22(1)
Опубликована: Янв. 17, 2025
<p><strong>Aim</strong> 3D printing technology revolutionises orthopaedic surgery by creating accurate patient-specific models, surgical guides, and implants. The COVID-19 pandemic accelerated this trend, allowing localized solutions biocompatible materials to replicate bone geometric complexity, enabling surgeons plan rehearse surgeries. This study aims illustrate the use of in preoperative planning a complex distal femur fracture.<br /><strong>Methods</strong> A 42-year-old woman with complicated Gustilo-Anderson grade III-A fracture underwent for implant planning, contouring, screw trajectory visualization. procedure took seven hours, lasted only two no complications or complaints during one-month follow-up.<br /><strong>Results</strong> has revolutionized better visualizing fractures, reducing time, enhancing precision. Traditional 2D imaging techniques struggle capture intricate details, requiring selection. However, challenges include high costs, specialized training. Further research is needed understand long-term outcomes.<br /><strong>Conclusion</strong> benefits surgery, including improved visualization, reduced precision, highlight its potential further advancement.</p>
Язык: Английский
Процитировано
0
Materials, Год журнала: 2025, Номер 18(3), С. 722 - 722
Опубликована: Фев. 6, 2025
The rising prevalence of orthopedic conditions, driven by an aging population, has led to a growing demand for advanced implant materials. Traditional metals such as stainless steel and titanium alloys are biologically inert often necessitate secondary surgical removal, imposing both economic psychological burdens on patients. Biodegradable zinc-based offer promising alternatives due their moderate degradation rates, biocompatibility, tissue-healing properties. However, existing studies Zn-Fe primarily focus composition optimization, with limited investigation into how processing methods influence performance. This study explores the effects rotary forging microstructure mechanical properties Zn-0.5Fe alloys. By refining grain structure promoting dynamic recrystallization, achieves significant improvements in ductility (60% elongation, 114% increase compared extruded state) while maintaining corrosion resistance. Electrochemical immersion tests reveal that produces denser more protective layer, thereby improving performance material simulated body fluid. Cytotoxicity fluorescence staining confirm excellent validating material’s suitability medical applications. These findings elucidate mechanisms which enhances alloys, providing novel approach tailoring biodegradable materials
Язык: Английский
Процитировано
0