Oncotarget, Год журнала: 2022, Номер 13(1), С. 1303 - 1304
Опубликована: Янв. 1, 2022
Язык: Английский
Heliyon, Год журнала: 2023, Номер 9(4), С. e15500 - e15500
Опубликована: Апрель 1, 2023
Around 10-15% of COVID-19 patients affected by the Delta and Omicron variants exhibit acute respiratory insufficiency require intensive care unit admission to receive advanced support. However, current ventilation methods display several limitations, including lung injury, dysphagia, muscle atrophy, hemorrhage. Furthermore, most ventilatory techniques currently offered highly trained professionals oxygen cylinders, which may attain short supply owing high demand misuse. Therefore, search for new alternatives therapeutics has become extremely important maintaining gas exchange in COVID-19. This review highlights suggest based on micro nanostructures capable supplying and/or enabling hematosis during moderate or cases.
Язык: Английский
Процитировано
6
Frontiers of Environmental Science & Engineering, Год журнала: 2024, Номер 18(12)
Опубликована: Сен. 30, 2024
Язык: Английский
Процитировано
2
Future Internet, Год журнала: 2022, Номер 14(12), С. 356 - 356
Опубликована: Ноя. 28, 2022
The development of nanomedicine involves complex nanomaterial research involving magnetic nanomaterials and their use in hyperthermia. selection the optimal treatment strategies is time-consuming, expensive, unpredictable, not consistently effective. Delivering personalized therapy that obtains maximal efficiency minimal side effects highly important. Thus, Artificial Intelligence (AI) based algorithms provide opportunity to overcome these crucial issues. In this paper, we briefly overview significance combination AI-based methods, particularly Machine Learning (ML) technique, with We considered recent publications, reports, protocols, review papers from Scopus Web Science Core Collection databases, considering PRISMA-S methodology on applying nanocarriers An algorithmic performance comparison terms types accuracy, data availability taking into account amount, types, quality was also carried out. Literature shows AI support studies physicochemical evaluation nanocarriers, drug release, resistance prediction, dosing optimization, selection, pharmacokinetic profile characterization, outcome prediction heat generation estimation. reviewed here clearly illustrate solutions can be as an effective supporting tool delivery, including optimization behavior both vitro vivo, well delivery process. Moreover, direction future research, experiments curation initiatives has been indicated.
Язык: Английский
Процитировано
9
Journal of Marine Science and Application, Год журнала: 2024, Номер 23(1), С. 39 - 48
Опубликована: Янв. 15, 2024
Abstract The compressibility of fluids has a profound influence on oscillating bubble dynamics, as characterized by the Mach number. However, current theoretical frameworks for bubbles, whether at first or second order number, are primarily confined to scenarios weak compressibility. Thus, critical need elucidate precise range applicability both first- and second-order theories arises. Herein, we investigate suitability constraints with different orders through comparative analysis involving experimental data numerical simulations. focal point our investigation encompasses such Rayleigh–Plesset, Keller, Herring, equations. Furthermore, impact parameters inherent in equations is examined. For spherical dynamics free field, findings reveal that applicable when Ma ⩽0.3 0.4, respectively. single sonoluminescence bubble, define an instantaneous i . theory shows abnormal sensibility high, which negligible ⩽0.4. results this study can serve valuable reference studying compressible dynamics.
Язык: Английский
Процитировано
1
Saudi Pharmaceutical Journal, Год журнала: 2021, Номер 29(10), С. 1181 - 1184
Опубликована: Сен. 21, 2021
As the world faces a fourth COVID-19 spike, scientists are learning lot more about new SARS-CoV-2 strains that were previously unknown. Currently, Delta versions of have become prevalent in much since it first appeared India late 2020. Researchers believe they discovered why has been so successful: those infected with create significantly virus than original strain SARS-CoV-2, making extremely contagious. This redirected focus to how our immune system defends us from these various pathogens and initiates such varied responses. Hundreds research papers published on origins long-lasting responses disparities numbers different cell types COVID 19 survivors, but primary architect discrepancies yet be discovered. In this essay, we will concentrate protein, activation induced cytidine deaminase (AID), which triggers molecular processes allow produce powerful antibodies specific B cells, allowing outwit virus. We if ever achieve permanent immunity infection, AID key releasing it.
Язык: Английский
Процитировано
7
International Journal of Medical Sciences, Год журнала: 2021, Номер 18(16), С. 3788 - 3793
Опубликована: Янв. 1, 2021
As the world is racing to develop perpetual immunity SARS-CoV-2 virus. The emergence of new viral strains, together with vaccination and reinfections, are all contributing a long-term against deadly virus that has taken over since its introduction humans in late December 2019. discovery more than 95 percent people who recovered from COVID-19 had long-lasting asymptomatic have different immune response symptomatic shifted attention how our system initiates such diverse responses. These findings provided reason believe days numbered. Hundreds research papers been published on causes responses variations numbers cell types COVID 19 survivors, but main these differences still not adequately identified. In this article, we focus activation-induced cytidine deaminase (AID), which molecular processes allow generate antibodies SARS-CoV-2. To establish lasting SARS-CoV-2, suggest AID could be key unlocking it.
Язык: Английский
Процитировано
7
Oncotarget, Год журнала: 2022, Номер 13(1), С. 1303 - 1304
Опубликована: Янв. 1, 2022
Язык: Английский
Процитировано
2