Polymeric Coatings and Antimicrobial Peptides as Efficient Systems for Treating Implantable Medical Devices Associated-Infections DOI Open Access
Irina Neguț, Bogdan Biță, Andreea Groza

и другие.

Polymers, Год журнала: 2022, Номер 14(8), С. 1611 - 1611

Опубликована: Апрель 15, 2022

Many infections are associated with the use of implantable medical devices. The excessive utilization antibiotic treatment has resulted in development antimicrobial resistance. Consequently, scientists have recently focused on conceiving new ways for treating a longer duration action and minimum environmental toxicity. One approach infection control is based coatings polymers peptides, also termed as “natural antibiotics”.

Язык: Английский

Antimicrobial Peptides, Their Production, and Potential in the Fight Against Antibiotic-Resistant Pathogens DOI Creative Commons
Margarita Saubenova, Alexander Rapoport, Zhanerke Yermekbay

и другие.

Fermentation, Год журнала: 2025, Номер 11(1), С. 36 - 36

Опубликована: Янв. 17, 2025

The article reviews the literature on antimicrobial peptides (AMPs) that exhibit unique mechanisms, such as broad-spectrum activity, low development of resistance, and ability to modulate immune response host organism. Information is provided significant potential AMPs in fight against pathogens threatening human health food safety. Enrichment diet with biologically active obtained using proteolytic activity lactic acid bacteria (LAB) proposed a simple, accessible, viable alternative antibiotics does not have harmful side effect. review briefly covers methods for obtaining features LAB system responsible producing bioactive environment. It has been shown various strains makes it possible produce high-quality whey-based beverages different directions antagonistic opportunistic helps optimize gastrointestinal microbiota. assumed drinks can reduce dose antimicrobials combined therapy infectious diseases be preventive measure contagion spread resistance.

Язык: Английский

Процитировано

1

Groundbreaking Technologies and the Biocontrol of Fungal Vascular Plant Pathogens DOI Creative Commons
Carmen Gómez‐Lama Cabanás, Jesús Mercado‐Blanco

Journal of Fungi, Год журнала: 2025, Номер 11(1), С. 77 - 77

Опубликована: Янв. 18, 2025

This review delves into innovative technologies to improve the control of vascular fungal plant pathogens. It also briefly summarizes traditional biocontrol approaches manage them, addressing their limitations and emphasizing need develop more sustainable precise solutions. Powerful tools such as next-generation sequencing, meta-omics, microbiome engineering allow for targeted manipulation microbial communities enhance pathogen suppression. Microbiome-based include design synthetic consortia transplant entire or customized soil/plant microbiomes, potentially offering resilient adaptable strategies. Nanotechnology has advanced significantly, providing methods delivery biological agents (BCAs) compounds derived from them through different nanoparticles (NPs), including bacteriogenic, mycogenic, phytogenic, phycogenic, debris-derived ones acting carriers. The use biodegradable polymeric non-polymeric eco-friendly NPs, which enable controlled release antifungal while minimizing environmental impact, is explored. Furthermore, artificial intelligence machine learning can revolutionize crop protection early disease detection, prediction outbreaks, precision in BCA treatments. Other genome editing, RNA interference (RNAi), functional peptides efficacy against pathogenic fungi. Altogether, these provide a comprehensive framework management diseases, redefining modern agriculture.

Язык: Английский

Процитировано

1

Food-derived bioactive peptides: The gateway to reach the full potential of food proteins for human health DOI
Ilekuttige Priyan Shanura Fernando, Jianping Wu

Trends in Food Science & Technology, Год журнала: 2025, Номер 157, С. 104896 - 104896

Опубликована: Янв. 31, 2025

Язык: Английский

Процитировано

1

Antimicrobial and Cell-Penetrating Peptides: Understanding Penetration for the Design of Novel Conjugate Antibiotics DOI Creative Commons
Andreas Hadjicharalambous, Nikolaos Bournakas, Hector Newman

и другие.

Antibiotics, Год журнала: 2022, Номер 11(11), С. 1636 - 1636

Опубликована: Ноя. 16, 2022

Antimicrobial peptides (AMPs) are short oligopeptides that can penetrate the bacterial inner and outer membranes. Together with cell-penetrating (CPPs), they called membrane active peptides; which translocate across biological Over last fifty years, attempts have been made to understand molecular features drive interactions of membranes peptides. This review examines a these exploit for translocation, as well physicochemical characteristics important translocation. Moreover, it presents examples how used in recent years create conjugates consisting peptide, “vector”, attached either current or novel antibiotic, “cargo” “payload”. In addition, discusses what properties may contribute an ideal peptide vector able deliver cargoes rising issue antimicrobial resistance demands new strategies be employed combat this global public health threat.

Язык: Английский

Процитировано

34

Polymeric Coatings and Antimicrobial Peptides as Efficient Systems for Treating Implantable Medical Devices Associated-Infections DOI Open Access
Irina Neguț, Bogdan Biță, Andreea Groza

и другие.

Polymers, Год журнала: 2022, Номер 14(8), С. 1611 - 1611

Опубликована: Апрель 15, 2022

Many infections are associated with the use of implantable medical devices. The excessive utilization antibiotic treatment has resulted in development antimicrobial resistance. Consequently, scientists have recently focused on conceiving new ways for treating a longer duration action and minimum environmental toxicity. One approach infection control is based coatings polymers peptides, also termed as “natural antibiotics”.

Язык: Английский

Процитировано

32