In
this
study,
we
identify
facilitators
and
barriers
to
COVID-19
vaccination
in
Nairobi,
Kenya,
using
the
modified
5
Cs
model
for
vaccine
hesitancy.
We
conducted
33
in-person
interviews
Kenya.
Participants
were
recruited
convenience
sampling
by
a
member
of
research
team
who
resides
Nairobi
speaks
Swahili.
Interviews
audio
recorded
transcripts
analyzed
thematic
analysis.
The
hesitancy
was
applied
create
codebook
prior
cited
misinformation,
lack
trust
science
behind
vaccine,
concerns
about
side
effects
as
reasons
not
receiving
vaccine.
Facilitators
choosing
receive
included
severity
COVID-19,
requirements
school
employment,
communication
from
government.
This
study
is
first
organize
uptake
Kenya
Our
findings
suggest
that
improve
interventions
should
inform
public
vaccine's
safety
reduce
misinformation.
Journal of Public Health,
Год журнала:
2022,
Номер
31(11), С. 1829 - 1845
Опубликована: Сен. 19, 2022
Abstract
Aim
Although
multiple
COVID-19
vaccines
are
approved
for
global
use,
vaccine
hesitancy
poses
a
substantial
risk
health.
Therefore,
the
aim
of
this
umbrella
review
is
to
identify
those
factors
that
influence
vaccination
in
general
population.
This
necessary
improve
effectiveness
future
programmes.
Methods
PubMed,
Embase,
Scopus,
PsycInfo,
Cochrane
Database
Systematic
Reviews,
Epistemonikos,
and
PROSPERO
(International
Prospective
Register
Reviews)
were
searched
on
December
21,
2021.
included
reviews
which
investigated
intention,
willingness,
or
with
regard
adult
populations,
no
restrictions
setting.
Content-based
structure
was
used
synthesise
extracted
data.
The
findings
presented
based
Strategic
Advisory
Group
Experts
(SAGE)
Working
Model
hesitancy.
Results
A
total
3,392
studies
identified,
31
met
inclusion
criteria.
most
frequently
documented
associated
contextual
factors,
such
as
sex,
age,
social
inequalities;
individual
group
trust
healthcare
system,
public
health
authorities,
governments,
history
vaccination;
vaccine-specific
concern
safety,
perceived
barriers,
vaccines,
about
rapid
development
vaccine;
disease-specific
fear
being
infected
COVID-19,
severity
knowledge
COVID-19.
Conclusion
There
Our
lay
foundation
further
understand
uptake
provide
possible
targets
intervention
However,
there
gaps
research
concerning
certain
including
people
mental
disorders.
Abstract
Background
Human
Papilloma
Virus
(HPV)
is
the
most
common
sexually
transmitted
infection
worldwide.
Globally,
both
men
and
women
have
a
50%
risk
of
being
infected
at
least
once
in
their
life.
HPV
prevalence
among
highest
sub-Saharan
Africa
(SSA),
an
average
24%.
causes
different
types
cancers,
including
cervical
cancer
(CC),
which
leading
cause
deaths
SSA.
HPV-vaccination
has
been
proven
to
be
effective
reducing
induced
cancers.
SSA
countries
are
delayed
reaching
WHO’s
target
fully
vaccinating
90%
girls
within
age
15
by
2030.
Our
systematic
review
aims
identify
barriers
facilitators
inform
national
implementation
strategies
region.
Methods
This
mixed
method
based
on
PRISMA
statement
The
Joanna
Briggs
Institute
Reviewers’
Manual.
Search
were
adapted
each
selected
database:
PubMed/MEDLINE,
Livivo,
Google
Scholar,
Science
Direct,
African
Journals
Online
for
papers
published
English,
Italian,
German,
French
Spanish
between
1
December
2011
31
2021.
Zotero
Rayyan
software
used
data
management.
appraisal
was
conducted
three
independent
reviewers.
Results
A
total
20
articles
from
initial
536
articles.
Barriers
included:
limited
health
system
capacities,
socio-economic
status,
stigma,
fear
costs
vaccines,
negative
experience
with
vaccinations,
COVID-19
pandemic,
lack
correct
information,
education
(HE)
consent.
Additionally,
we
found
that
boys
scarcely
considered
parents
stakeholders.
Facilitators
information
knowledge,
policy
implementation,
positive
HE,
stakeholders’
engagement,
women’s
empowerment,
community
seasonality,
target-oriented
vaccination
campaigns.
Conclusions
synthesizes
HPV-vaccinations
Addressing
these
can
contribute
more
immunization
programs
targeted
eliminating
CC
line
WHO
90/70/90
strategy.
Registration
funding
Protocol
ID:
CRD42022338609
registered
International
Prospective
Register
Systematic
Reviews
(PROSPERO).
Partial
funds:
German
Centre
Infection
research
(DZIF)
project
NAMASTE:
8,008,803,819.
PLoS ONE,
Год журнала:
2023,
Номер
18(4), С. e0280439 - e0280439
Опубликована: Апрель 12, 2023
Healthcare
workers
(HCWs)
and
healthcare
students
display
high
levels
of
vaccine
hesitancy
with
impact
on
provision,
patient
safety,
health
promotion.
The
factors
related
to
have
been
reported
in
several
systematic
reviews.
However,
this
evidence
needs
be
synthesised,
as
interventions
reduce
vaccination
population
are
needed.
Globalization and Health,
Год журнала:
2024,
Номер
20(1)
Опубликована: Фев. 6, 2024
Abstract
Introduction
Indonesia
has
made
progress
in
increasing
vaccine
coverage,
but
equitable
access
remains
challenging,
especially
remote
areas.
Despite
including
vaccines
the
National
Immunization
Program
(NIP),
coverage
not
met
WHO
and
UNICEF
targets,
with
childhood
immunization
decreasing
during
COVID-19
pandemic.
vaccination
also
experienced
hesitancy,
slowing
efforts
to
end
Scope
This
article
addresses
issue
of
hesitancy
its
impact
on
initiatives
amidst
utilizes
framework
analyze
previous
outbreaks
vaccine-preventable
diseases
their
underlying
causes,
ultimately
providing
recommendations
for
addressing
current
situation.
The
analysis
considers
differences
between
pre-pandemic
circumstances
present
implementation
basic
advanced
strategies.
Key
findings
conclusion
Vaccine
is
a
significant
challenge
pandemic,
public
health
campaigns
community
engagement
are
needed
promote
acceptance
uptake.
Efforts
address
trust
healthcare
systems
increase
likelihood
individuals
seeking
preventive
services.
requires
comprehensive,
culturally
sensitive
approach
that
local
contexts
realities.
Strategies
should
be
tailored
specific
cultural
societal
monitored
evaluated.
Viruses,
Год журнала:
2022,
Номер
14(11), С. 2519 - 2519
Опубликована: Ноя. 14, 2022
Hong
Kong
SAR
has
adopted
universal
masking,
social
distancing,
testing
of
all
symptomatic
and
high-risk
groups
for
isolation
confirmed
cases
in
healthcare
facilities,
quarantine
contacts
as
epidemiological
control
measures
without
city
lockdown
or
border
closure.
These
successfully
suppressed
the
community
transmission
pre-Omicron
SARS-CoV-2
variants
lineages
during
first
to
fourth
wave.
No
nosocomial
infection
was
documented
among
workers
300
days.
The
strategy
COVID-19
containment
provide
additional
time
achieve
population
immunity
by
vaccination.
near-zero
situation
about
8
months
2021
did
not
enable
adequate
immunization
eligible
population.
A
combination
factors
identified,
especially
complacency
associated
with
low
local
activity,
together
vaccine
hesitancy.
importation
highly
transmissible
Omicron
variant
kickstarted
fifth
wave
COVID-19,
which
could
no
longer
be
controlled
our
initial
measures.
explosive
wave,
partially
contributed
vertical
airborne
high-rise
residential
buildings,
resulted
over
one
million
infection.
In
this
review,
we
summarize
epidemiology
public
health
against
dissemination
until
day
1000.
PLOS Global Public Health,
Год журнала:
2024,
Номер
4(3), С. e0002986 - e0002986
Опубликована: Март 28, 2024
COVID-19
vaccination
rates
have
been
low
among
adults
in
Kenya
(36.7%
as
of
late
March
2023)
with
vaccine
hesitancy
posing
a
threat
to
the
program.
This
study
sought
examine
facilitators
and
barriers
vaccinations
Kenya.
We
conducted
qualitative
cross-sectional
two
purposively
selected
counties
collected
data
through
8
focus
group
discussions
80
community
members
in-depth
interviews
health
care
managers
providers.
The
was
analyzed
using
framework
approach
focusing
on
determinants
their
influence
psychological
constructs.
Barriers
uptake
were
related
individual
characteristics
(males,
younger
age,
perceived
status,
belief
herbal
medicine,
lack
autonomy
decision
making
women
‐
especially
rural
settings),
contextual
influences
(lifting
bans,
myths,
medical
mistrust,
cultural
religious
beliefs),
factors
(fear
unknown
consequences,
side-effects,
understanding
how
vaccines
work
rationale
for
boosters).
However,
volunteers,
trusted
leaders,
mandates,
financial
geographic
access
influenced
uptake.
These
drivers
mainly
constructs
including
confidence,
complacency,
constraints.
Vaccine
is
driven
by
multiple
interconnected
factors.
are
likely
inform
evidence-based
targeted
strategies
that
built
trust
address
hesitancy.
could
include
gender
responsive
immunization
programs,
appropriate
messaging
consistent
communication
target
fear,
safety
concerns,
misconceptions
information
gaps
line
concerns.
There
need
ensure
tested
local
setting
incorporate
multisectoral
leaders
leaders.
Vaccines,
Год журнала:
2023,
Номер
11(2), С. 465 - 465
Опубликована: Фев. 17, 2023
COVID-19
is
a
major
public
health
threat
associated
with
the
increased
global
burden
of
infectious
diseases,
mortality,
and
enormous
economic
loss
to
countries
communities.
Safe
efficacious
vaccines
are
crucial
in
halting
pandemic.
We
assessed
vaccine
uptake
factors
among
community
members
from
eight
regions
Tanzania.
The
interviewer-administered
questionnaire
collected
data.
Multiple
logistic
regression
models
determined
uptake.
median
age
3470
respondents
was
37
years
(interquartile
range
29-50
years)
66%
them
were
females.
Only
18%
had
received
vaccine,
ranging
8%
Dar
es
Salaam
37%
Simiyu
regions.
A
third
(34%)
those
vaccinated
people
did
not
know
which
they
given.
Significantly
higher
rates
aged
30+
years,
males,
history
infection.
Unfavorable
perceptions
about
safety
efficacy
lowered
Setting-specific
interventions
innovations
critical
improving
uptake,
given
observed
differences
between
Efforts
needed
increase
women
younger
less
than
30
years.
Knowledge-based
should
enhance
understanding
available
vaccines,
benefits,
target
groups,
availability.
Frontiers in Public Health,
Год журнала:
2024,
Номер
12
Опубликована: Янв. 17, 2024
Introduction
Although
the
burden
of
cervical
cancer
in
Africa
is
highest,
HPV
vaccination
coverage
remains
alarmingly
low
this
region.
Providers’
knowledge
and
recommendation
are
key
drivers
uptake.
Yet,
evidence
about
providers’
practices
vaccine
against
a
backdrop
emerging
hesitancy
fueled
by
COVID-19
pandemic
lacking
Africa.
Methods
A
cross-sectional
study
was
conducted
2021–2022
among
healthcare
providers
involved
prevention
activities
They
were
invited
to
report
prior
training,
availability
their
practice,
whether
they
recommended
vaccine,
and,
if
not,
reasons
for
not
recommending
it.
Their
assessed
through
self-reporting
(perceived
knowledge)
with
three
pre-tested
questions
(measured
knowledge).
Results
Of
153
from
23
African
countries
who
responded
survey
(mean
age:
38.5
years,
SD:
10.1),
75
(54.0%)
female
97
(63.4%)
based
In
national
immunization
programs.
Overall,
57
(43.8%)
reported
having
received
training
on
education/counseling,
40
(37.4%)
indicated
that
available
at
facility
where
work.
Most
respondents
(109,
83.2%)
practice.
Vaccine
unavailability
(57.1%),
lack
effective
communication
tools
informational
material
(28.6%),
need
adequate
(28.6%)
most
commonly
vaccine.
While
63
(52.9%)
only
9.9%
correctly
3
questions.
Conclusion
To
increase
counter
misinformation
Africa,
culturally
appropriate
educational
materials
needed
improve
facilitate
patients
community.
Scientific Reports,
Год журнала:
2024,
Номер
14(1)
Опубликована: Апрель 26, 2024
This
study
assessed
the
association
among
knowledge,
attitudes
and
uptake
of
COVID-19
vaccine
in
Malawi,
examining
demographic
factors
influencing
these
variables.
The
employed
a
quantitative
research
design.
It
thus
sampled
394
participants
from
Malawi's
three
districts
Zomba,
Dowa
Nkhatabay.
Results
showed
that
163
(41.4%)
had
low
levels
knowledge
vaccine,
231
(58.6%)
high
237
(60.2%)
positive
attitude,
156
(39.8%)
negative
attitude
towards
vaccine.
On
uptake,
found
only
29
(17%)
male
52
(23%)
female
received
Further,
with
were
5.9
times
more
likely
(p-value
=
0.001)
to
be
vaccinated
than
those
other
hand,
8.2
<
compared
findings
highlight
importance
vaccine-related
shaping
reveal
disparities
across
groups.
To
improve
vaccination
coverage
targeted
interventions
focusing
on
enhancing
addressing
attitudinal
barriers,
countering
misinformation
are
needed.
Strategies
should
tailored
reach
populations
lower
such
as
males,
younger
adults,
education
levels.
Strengthening
public
health
messaging,
engaging
community
leaders,
building
trust
healthcare
systems
crucial
for
promoting
widespread
acceptance
vaccines
Malawi.