Foods,
Год журнала:
2024,
Номер
13(10), С. 1488 - 1488
Опубликована: Май 11, 2024
Live
vinegar
is
a
product
formed
through
two-step
fermentation
process
of
sugar
substrate
that
has
not
been
subjected
to
filtration
or
pasteurization.
This
considered
preserve
all
nutrients
and
biologically
active
microorganisms,
making
it
with
valuable
composition
beneficial
properties.
Therefore,
the
purpose
this
study
was
analyze
chemical
antioxidant
properties
selected
vinegars
available
on
Polish
food
market.
The
material
in
consisted
four
live
(naturally
turbid,
unfiltered,
unpasteurized)
fruit
vegetable
vinegars:
apple,
pear,
rhubarb,
lemon.
Spectrophotometric,
HPLC,
GC
methods
were
used.
Among
tested,
lemon
had
highest
vitamin
C
content—15.95
mg/100
mL.
Apple
proved
be
best
source
polyphenols
flavonoids
(TPC—191.97
mg
GAE/L,
TFC—70.22
RE/L).
All
contained
dihydroxybenzoic
acid,
4-hydroxybenzoic
caffeic
2-hydroxycinnamic
myricetin.
acetic
acid
content
tested
ranged
from
29.180
38.125
mM/L.
pH
values
3.14
3.41.
In
conclusion,
most
promising
nutraceutical
potentially
health-promoting
seems
apple
vinegar.
Nutrients,
Год журнала:
2024,
Номер
16(12), С. 1964 - 1964
Опубликована: Июнь 20, 2024
The
consumption
of
almonds
has
been
associated
with
several
health
benefits,
particularly
concerning
cardiovascular
and
intestinal
health.
In
this
comprehensive
review,
we
compile
deliberate
studies
investigating
the
effects
almond
on
disease
(CVD)
risk
factors
gut
Almonds
are
rich
in
monounsaturated
fats,
fiber,
vitamins,
minerals,
polyphenols,
which
contribute
to
their
health-promoting
properties.
Regular
intake
shown
improve
lipid
profiles
by
reducing
LDL
cholesterol
enhancing
HDL
functionality.
Additionally,
aid
glycemic
control,
blood
pressure
reduction,
chronic
inflammation
amelioration,
critical
for
antioxidant
properties
almonds,
primarily
due
high
vitamin
E
content,
help
oxidative
stress
markers.
Furthermore,
positively
influence
body
composition
fat
percentage
central
adiposity
satiety,
thus
aiding
weight
management.
Herein,
also
contemplate
emerging
concept
gut–heart
axis,
where
appears
modulate
microbiome,
promoting
growth
beneficial
bacteria
increasing
short-chain
fatty
acid
production,
butyrate.
These
collectively
anti-inflammatory
cardioprotective
benefits
almonds.
By
encompassing
these
diverse
aspects,
eventually
provide
a
systematic
updated
perspective
multifaceted
corroborating
broader
consideration
dietary
guidelines
public
recommendations
CVD
reduction.
Triphala
is
an
Ayurvedic
herbal
formulation
used
to
treat
gastrointestinal
disorders.
The
present
study
explored
the
underlying
mechanisms
of
against
integrated
and
neurological
disorders
through
network
pharmacology
molecular
docking.
Components
were
screened
using
Dr.
Duke's
Phytochemical
Ethnobotanical
Database,
KNApSAcK
database,
Indian
Medicinal
Plants,
Phytochemistry
Therapeutics
database
while
target
prediction
was
done
SuperPred
3.0,
followed
by
mapping
with
shared
targets
obtained
from
GeneCards
DisGenet
databases.
STRING
Cytoscape
utilized
for
protein–protein
protein-target
interaction
analyses
further
screening
core
clusters.
GO,
KEGG,
Reactome
enrichment
analysis
performed,
top
subject
binding
affinity
evaluation
major
compounds.
Based
on
ADME
characteristics,
seven
components
overlapped
104
genes
STAT3,
ESR1,
HIF1A,
MTOR,
PPARG,
MAP2K2,
TLR4,
SLC2A1,
NFKB1,
ESR1
revealed
as
interacting
nodes
interaction,
compound-target
compound-target-disease-pathway
analysis.
GO
indicated
involved
in
managing
cell
response
stress,
stimuli,
metabolism
KEGG
pathways
related
cancer,
metabolism,
signalling.
implied
immune
system,
signalling,
disease
pathways.
Thannilignan,
7-Hydroxy-3',4'-methylenedioxyflavan,
Termilignan
identified
phytocompounds
Triphala.
Molecular
docking
excellent
interactions
all
analysed
receptors
mean
energies
ranging
−
7.58
8.34
kcal/mol/receptor
which
most
notable
compound
7-Hydroxy-3',4'-methylenedioxyflavan.
Together,
this
work
delineates
identifies
new
drug
candidates
management
Journal of Advanced Research,
Год журнала:
2025,
Номер
unknown
Опубликована: Март 1, 2025
Traditionally,
the
mechanism
of
dark
tea
quality
formation
has
centered
on
microorganisms,
with
regulated
by
manipulating
microorganisms
and
their
fermentation
environment.
Nevertheless,
raw
teas,
natural
selective
medium
microbial
community,
was
completely
ignored
in
unique
flavors.
This
study
aims
to
uncover
previously
unappreciated
interactions
between
demonstrating
significant
role
quality.
Sun-dried
(SDT),
baked
(BT),
pan-fried
(PFT)
were
pile
fermented.
Chemical
profiles,
communities,
sensory
qualities
assessed
metabolomics,
high-throughput
sequencing,
evaluation,
correlation
multiple
factor
analyses
used
explore
relationships.
Compared
PFT
BT,
SDT
had
18
%
lower
flavonoid
content
26
catechin
content,
which
favored
dominant
Agathobacter
Wickerhamomyces.
Wickerhamomyces
contributed
flower
aroma
producing
alcohols,
esters
terpenes,
while
amplified
acid
production.
The
distinctive
bacterium
Acidovorax
BT
positively
correlated
alcohols
hydrocarbons,
Pearson's
r
>
0.6,
resulting
a
47
increase
volatile
alcohol
level,
enhancing
fresh
refreshing
attributes.
A
70-80
iron
concentration
compared
resulted
predominance
Geobacter,
exhibited
negative
aldehydes.
presence
bacteria,
Streptococcus
Ligilactobacillus,
led
rise
increasing
from
5
25
%.
chemical
profiles
could
reshape
local
microbiota,
then
drives
tea.
indicates
is
not
passively
shaped
environmental
but
actively
screened
chemistry.
paves
way
for
targeted
manipulation
achieve
desired
flavor
characteristics.
Current Opinion in Biotechnology,
Год журнала:
2024,
Номер
86, С. 103073 - 103073
Опубликована: Фев. 9, 2024
Although
probiotics
have
been
used
in
food
products
and
supplements
for
decades,
there
has
a
considerable
increase
their
use
more
recently.
Recent
technological
advances
thus
led
to
major
knowledge
of
the
gut
microbiota,
enabling
significant
development
biotics.
In
this
review,
we
discuss
uses
traditional
but
also
discovery
next-generation
that
could
be
as
live
biotherapeutics.
These
novel
preventive
therapeutic
strategies
hold
promise
treatment
numerous
diseases
such
inflammatory
bowel
Crohn's
disease
ulcerative
colitis.
Probiotic
bacteria
can
consumed
alone,
or
combination
with
prebiotics
synbiotics,
mixed
other
probiotic
strains
form
consortium
enhanced
effects.
We
benefits
using
postbiotics.
Foods,
Год журнала:
2024,
Номер
13(7), С. 992 - 992
Опубликована: Март 25, 2024
Epigallocatechin-3-gallate
(EGCG),
a
prominent
polyphenol
found
abundantly
in
tea,
has
garnered
significant
attention
for
its
potential
preventing
and
ameliorating
wide
range
of
diseases.
Its
remarkable
antioxidant
properties
ability
to
capture
reactive
carbonyl
species
make
it
key
player
among
tea’s
polyphenolic
components.
This
paper
delves
into
the
synthesis
origins
both
EGCG
(RCS),
emphasizing
toxicity
RCS
various
food
sources
their
formation
during
processing.
Understanding
EGCG’s
capability
metabolize
is
crucial
harnessing
health
benefits.
Thus,
this
explores
underlying
mechanisms
inhibition
role
capturing
these
compounds
generate
EGCG-RCS
adducts.
And
absorption
metabolism
adducts
also
discussed.
Critical Reviews in Food Science and Nutrition,
Год журнала:
2024,
Номер
unknown, С. 1 - 16
Опубликована: Дек. 4, 2024
Flavonoids,
a
class
of
polyphenolic
compounds,
are
widely
distributed
in
plant-based
foods
and
have
been
recognized
for
their
potential
to
promote
overall
health
well-being.
Flavonoids
fruits
vegetables
offer
various
beneficial
effects
such
as
anti-aging,
anticancer,
anti-inflammatory
properties.
extensively
studied
neuroprotective
properties,
which
attributed
ability
cross
the
blood-brain
barrier
interact
with
neural
cells.
Factors
like
gut
microbiota
composition,
age,
genetics,
diet
can
impact
how
well
flavonoids
absorbed
gut.
The
enhance
absorption
through
enzymatic
processes,
making
composition
key
factor
influenced
by
diet.
modulate
prebiotic
antimicrobial
effects,
affecting
production
microbial
metabolites
short-chain
fatty
acids
(SCFAs)
butyrate,
play
role
brain
function
health.
microbiome
also
modulates
immune
system,
is
critical
preventing
neuroinflammation.
Additionally,
benefit
mental
psychological
influencing
signaling
pathways
cells
increasing
tyrosine
tryptophan,
precursors
neurotransmitters
serotonin,
dopamine,
norepinephrine,
adrenaline,
gamma-aminobutyric
acid
(GABA).
flavonoid-gut
axis
complex
multifaceted
relationship
that
has
significant
implications
neurological
This
review
will
explore
genetic
environmental
factors
flavonoid
positive
on
network.
