Unraveling the Impact of COVID-19 on Rheumatoid Arthritis: Insights from Two Romanian Hospitals—Preliminary Results
Biomedicines,
Год журнала:
2024,
Номер
12(9), С. 2145 - 2145
Опубликована: Сен. 21, 2024
Rheumatoid
arthritis
(RA)
patients
are
at
heightened
risk
of
Coronavirus
Disease-19
(COVID-19)
complications
due
to
immune
dysregulation,
chronic
inflammation,
and
treatment
with
immunosuppressive
therapies.
This
study
aims
characterize
the
clinical
laboratory
parameters
RA
diagnosed
COVID-19,
identify
predictive
factors
for
severe
forms
this
infection
patients,
determine
if
any
therapy
is
associated
worse
COVID-19
outcomes.
Язык: Английский
Inflammation Indexes PLR, SII, AISI, MLR, NLPR and MCVL in Peripartum Treated Thrombophilia Patients Undergoing Cesarean Section at Term-STROBE Compliant
Опубликована: Март 14, 2024
(1)
Background:
Thrombophilia
is
a
tendency
towards
hypercoagulability,
and
it
increased
by
pregnancy,
peaking
around
delivery.
Research
question:
does
thrombophilia
stimulate
the
in-flammatory
state
of
patient,
already
suppressed
pregnancy?
(2)
Methods:
Eighty
thrombo-philia
patients
admitted
for
delivery
between
1/10/2017
1/12/2021
were
prospectively
stud-ied,
together
with
eighty
age-
para-matched
control
patients.
Patients
de-livery
at
term
means
cesarean
section.
The
inflammation
indexes
from
complete
blood
count
values
analysis
during
both
24
hours
before
after
labor—extracted
hospi-tal’s
medical
records—were
calculated
then
correlated
uterine
involution.
(3)
Results:
Except
PLR,
most
numerous
studied
not
significantly
different
in
treated
patients,
delivery,
compared
to
non-thrombophilia
Only
when
we
split
based
on
haematometra
first
24-48
postpartum,
found
out
that
few
(14
79
thrombophilia)
had
elevated
SII
AISI
antepartum.
In
pregnant
thrombophilia,
MLR
higher
pa-tients
without
Rh
factor
than
those
factor.
MCVL
NLPR
age
labor,
while
postpartum.
(4)
Conclusions:
did
inflammatory
pa-tient,
pregnancy.
Язык: Английский
Inflammation Indexes PLR, SII, AISI, MLR, and MCVL in Peripartum Treated Thrombophilia Peripartum Patients Undergoing Cesarean Section at Term
Опубликована: Ноя. 3, 2023
(1)
Background:
Thrombophilia
is
a
tendency
towards
hypercoagulability,
and
it
increased
by
pregnancy,
peaking
around
delivery.;
(2)
Methods:
80
Eighty
thrombophilia
patients
admitted
for
delivery
between
1/10/2017
1/12/2021
were
prospectively
studied,
together
with
eighty
age-
para-matched
control
patients.
Patients
at
term
means
of
cesarean
section.
The
inflammation
indexes
from
the
complete
blood
count
values
analysis,
in
during
both
24
hours
before
after
labor—,
extracted
hospital’s
medical
records—,
calculated,
then
correlated
uterine
involution.;
(3)
Results:
In
pregnant
treated
patients,
who
did
not
manage
to
have
close
their
cavity
closed
first
24-48
had
significantly
higher
SII
AISI
,
than
onesthose
cavity.
MLR
without
Rh
factor
those
factor.
non-thrombophilia
PLR
was
as
compared
MCVL
age
and,
labor,
while
age,
postpartum.
;
(4)
Conclusions:
There
may
be
an
underlying
state
that
persisted
despite
treatment
some
Язык: Английский