A
recent
study
demonstrated
that
noninvasive
measurements
of
cortical
hemodynamics
and
metabolism
in
the
resting
human
prefrontal
cortex
can
facilitate
quantitative
metrics
unilateral
mitochondrial-hemodynamic
coupling
bilateral
connectivity
infraslow
oscillation
(ISO)
frequencies
young
adults
(YA).
The
ISO
includes
three
distinct
vasomotions
with
endogenic
(E),
neurogenic
(N),
myogenic
(M)
frequency
bands.
goal
this
was
to
prove
hypothesis
there
are
significant
differences
between
older
(OA)
(uCOP)
(bCON)
cortex.
Accordingly,
we
performed
from
24
OA
(67.2
±
5.9
years
age)
using
same
2-channel
broadband
near-infrared
spectroscopy
(bbNIRS)
setup
resting-state
experimental
protocol
as
those
(Shahdadian
et
al,
Cerebral
Cortex
Communications,
2022).
After
quantification
uCOP
bCON
E/N/M
statistical
analysis,
had
significantly
weaker
hemodynamic
but
stronger
metabolic
than
YA
M
band.
Furthermore,
exhibited
on
both
sides
all
bands,
particularly
a
very
large
effect
size
band
(>
1.9).
These
age-related
results
clearly
support
our
were
well
interpreted
following
neurophysiological
principles.
key
finding
paper
is
highly
associated
age
may
have
potential
become
meaningful
features
for
brain
health
be
translatable
future
clinical
applications,
such
early
detection
Alzheimer’s
disease.
Frontiers in Neuroergonomics,
Год журнала:
2024,
Номер
4
Опубликована: Янв. 2, 2024
While
still
relatively
rare,
longitudinal
hyperscanning
studies
are
exceptionally
valuable
for
documenting
changes
in
inter-brain
synchrony,
which
may
turn
underpin
how
behaviors
develop
and
evolve
social
settings.
The
generalizability
ecological
validity
of
this
experimental
approach
hinges
on
the
selected
imaging
technique
being
mobile–a
requirement
met
by
functional
near-infrared
spectroscopy
(fNIRS).
fNIRS
has
most
frequently
been
used
to
examine
development
synchrony
behavior
child-parent
dyads.
In
position
paper,
we
contend
that
dedicating
attention
intergenerational
stands
benefit
fields
cognitive
neuroscience
more
broadly.
We
argue
is
particularly
relevant
understanding
neural
mechanisms
underpinning
dynamics,
potentially
benchmarking
progress
psychological
interventions,
many
situated
contexts.
line
with
our
position,
highlight
areas
research
stand
be
enhanced
mobile
devices,
describe
challenges
arise
from
measuring
across
generations
real
world,
offer
potential
solutions.
Biomedical Optics Express,
Год журнала:
2024,
Номер
15(4), С. 2110 - 2110
Опубликована: Янв. 2, 2024
A
feature
issue
is
being
presented
by
a
team
of
guest
editors
containing
papers
based
on
contributed
submissions
including
studies
at
Optics
and
the
Brain,
held
April
24-27,
2023
as
part
Optica
Biophotonics
Congress:
in
Life
Sciences,
Vancouver,
Canada.
Journal of Biophotonics,
Год журнала:
2024,
Номер
17(7)
Опубликована: Апрель 24, 2024
Abstract
Focal
damage
due
to
stroke
causes
widespread
abnormal
changes
in
brain
function
and
hemispheric
asymmetry.
In
this
study,
functional
near‐infrared
spectroscopy
(fNIRS)
was
used
collect
resting‐state
hemoglobin
data
from
85
patients
with
subacute
26
healthy
controls,
comparatively
analyze
the
characteristics
of
lateralization
after
terms
cortical
activity,
networks,
hemodynamic
lags.
Higher
intensity
motor
lower
autonomy,
more
leads
or
lags
were
found
affected
hemisphere.
Lateralization
metrics
three
aspects
all
associated
Fugl‐Meyer
score.
The
results
study
prove
that
may
provide
clinical
reference
for
rehabilitation.
Meanwhile,
present
piloted
use
fNIRS
analyzing
lag,
demonstrating
potential
assess
abnormalities
addition
neurological
stroke.
Medical Science Monitor,
Год журнала:
2024,
Номер
30
Опубликована: Май 6, 2024
Stroke
is
a
cerebrovascular
disease
that
impairs
blood
supply
to
localized
brain
tissue
regions
due
various
causes.This
leads
ischemic
and
hypoxic
lesions,
necrosis
of
the
tissue,
variety
functional
disorders.Abnormal
cortical
activation
connectivity
occur
in
after
stroke,
but
patterns
reorganization
are
not
well
understood.Rehabilitation
interventions
can
enhance
recovery
stroke
patients.However,
clinicians
require
objective
measures
support
their
practice,
as
outcome
for
based
on
scale
scores.Furthermore,
most
effective
rehabilitation
treating
patients
yet
be
investigated.Functional
near-infrared
spectroscopy
(fNIRS)
non-invasive
neuroimaging
method
detects
changes
cerebral
hemodynamics
during
task
performance.It
widely
used
neurological
research
clinical
practice
its
safety,
portability,
high
motion
tolerance,
low
cost.This
paper
briefly
introduces
imaging
principle
advantages
disadvantages
fNIRS
summarize
application
post-stroke
rehabilitation.
BMJ Open,
Год журнала:
2024,
Номер
14(2), С. e079372 - e079372
Опубликована: Фев. 1, 2024
Transcranial
direct
current
stimulation
(tDCS)
is
a
non-invasive
brain
technique
that
modulates
states
by
applying
weak
electrical
to
the
cortex.
Several
studies
have
shown
anodal
of
ipsilesional
primary
motor
cortex
(M1)
may
promote
recovery
affected
upper
limb
in
patients
with
stroke;
however,
high-level
clinical
recommendation
cannot
be
drawn
view
inconsistent
findings.
A
priming
protocol
has
been
proposed
induce
stable
modulatory
effects,
which
an
inhibitory
applied
prior
excitatory
area.
Our
recent
work
showed
theta
burst
magnetic
demonstrated
superior
effects
improving
function
and
neurophysiological
outcomes.
However,
it
remains
unknown
whether
pairing
session
cathodal
tDCS
will
also
capitalise
on
its
therapeutic
effects.
This
two-arm
double-blind
randomised
controlled
trial
involving
134
1-6
months
after
stroke
onset.
Eligible
participants
randomly
allocated
receive
10
sessions
tDCS+robotic
training,
or
non-priming
training
for
2
weeks.
The
outcome
Fugl-Meyer
Assessment-upper
extremity,
secondary
outcomes
are
Wolf
Motor
Function
Test
Modified
Barthel
Index.
motor-evoked
potentials,
regional
oxyhaemoglobin
level
resting-state
functional
connectivity
between
bilateral
M1
acquired
analysed
investigate
neuroplasticity.
study
approved
Research
Ethics
Committee
Shanghai
Yangzhi
Rehabilitation
Center
(reference
number:
Yangzhi2023-022)
conducted
accordance
Declaration
Helsinki
1964,
as
revised
2013.
ChiCTR2300074681.
Scientific Reports,
Год журнала:
2024,
Номер
14(1)
Опубликована: Июль 30, 2024
With
the
growing
interest
in
establishing
brain-based
biomarkers
for
precision
medicine,
there
is
a
need
noninvasive,
scalable
neuroimaging
devices
that
yield
valid
and
reliable
metrics.
Kernel's
second-generation
Flow2
Time-Domain
Functional
Near-Infrared
Spectroscopy
(TD-fNIRS)
system
meets
requirements
of
noninvasive
neuroimaging,
uses
validated
modality
to
measure
brain
function.
In
this
work,
we
investigate
test-retest
reliability
(TRR)
set
metrics
derived
from
recordings.
We
adopted
repeated-measures
design
with
49
healthy
participants,
quantified
TRR
over
multiple
time
points
different
headsets—in
experimental
conditions
including
resting
state,
sensory,
cognitive
task.
Results
demonstrated
high
state
features
hemoglobin
concentrations,
head
tissue
light
attenuation,
amplitude
low
frequency
fluctuations,
functional
connectivity.
Additionally,
passive
auditory
Go/No-Go
inhibitory
control
tasks
each
exhibited
similar
activation
patterns
across
days.
Notably,
areas
highest
were
regions
during
task,
right
prefrontal
consistent
prior
literature.
This
study
underscores
Flow2-derived
metrics,
supporting
its
potential
actualize
vision
using
diagnosis,
treatment
selection
monitoring
neuropsychiatric
neurocognitive
disorders.
Journal of Biophotonics,
Год журнала:
2024,
Номер
17(5)
Опубликована: Фев. 1, 2024
Abstract
The
objective
of
this
study
was
to
investigate
brain
activation
and
functional
network
patterns
during
musical
interventions
in
different
frequency
bands
using
near‐infrared
spectroscopy,
provide
a
basis
for
more
effective
music
therapy
strategy
selection
patients
minimally
conscious
state
(MCS).
Twenty
six
MCS
20
healthy
people
were
given
intervention
with
low
(31–180
Hz),
medium
(180–4k
high
(4k–22k
Hz)
audio.
In
patients,
induced
left
prefrontal
cortex
primary
sensory
(S1),
also
left‐hemisphere
lateralization
effect
dorsolateral
(DLPFC).
And
the
connectivity
right
DLPFC‐right
S1
significantly
improved
by
intervention.
may
contribute
than
recovery
consciousness.
This
validated
effectiveness
fNIRS
studies
function
patients.
bioRxiv (Cold Spring Harbor Laboratory),
Год журнала:
2024,
Номер
unknown
Опубликована: Март 14, 2024
Abstract
With
the
growing
interest
in
establishing
brain-based
biomarkers
for
precision
medicine,
there
is
a
need
noninvasive,
scalable
neuroimaging
devices
that
yield
valid
and
reliable
metrics.
Kernel’s
second-generation
Flow2
Time-Domain
Functional
Near-Infrared
Spectroscopy
(TD-fNIRS)
system
meets
requirements
of
noninvasive
neuroimaging,
uses
validated
modality
to
measure
brain
function.
In
this
work,
we
investigate
test-retest
reliability
(TRR)
set
metrics
derived
from
recordings.
We
adopted
repeated-measures
design
with
49
healthy
participants,
quantified
TRR
over
multiple
time
points
different
headsets—in
experimental
conditions
including
resting
state,
sensory,
cognitive
task.
Results
demonstrated
high
state
features
hemoglobin
concentrations,
head
tissue
light
attenuation,
amplitude
low
frequency
fluctuations,
functional
connectivity.
Additionally,
passive
auditory
Go/No-Go
inhibitory
control
tasks
each
exhibited
similar
activation
patterns
across
days.
Notably,
areas
highest
were
regions
during
task,
right
prefrontal
consistent
prior
literature.
This
study
underscores
Flow2-derived
metrics,
supporting
its
potential
actualize
vision
using
diagnosis,
treatment
selection
monitoring
neuropsychiatric
neurocognitive
disorders.
Scientific Reports,
Год журнала:
2024,
Номер
14(1)
Опубликована: Сен. 27, 2024
Intraventricular
hemorrhage
(IVH)
is
a
common
neurological
injury
following
very
preterm
birth.
Resting-state
functional
connectivity
(RSFC)
using
magnetic
resonance
imaging
(fMRI)
associated
with
severity;
yet,
fMRI
impractical
for
use
in
intensive
care
settings.
Functional
near-infrared
spectroscopy
(fNIRS)
measures
RSFC
through
cerebral
hemodynamics
and
has
greater
bedside
accessibility
than
fMRI.
We
evaluated
neonates
IVH
fNIRS
at
term-equivalent
age,
compared
between
healthy
newborns
those
IVH.
Sixteen
born
were
scanned
fNIRS.
Additionally,
fifteen
In
preterms
IVH,
maps
Euclidean
Jaccard
distances.
The
severity
of
relation
to
fNIRS-RSFC
strength
was
examined
generalized
linear
models.
showed
good
correspondence.
Connectivity
significantly
lower
(p-value
=
0.023)
infants
mild
0.026)
moderate/severe
potential
be
new
tool
assessing
brain
monitoring
hemodynamics,
as
well
promising
biomarker
infants.
Bioengineering,
Год журнала:
2023,
Номер
10(11), С. 1336 - 1336
Опубликована: Ноя. 20, 2023
A
recent
study
demonstrated
that
noninvasive
measurements
of
cortical
hemodynamics
and
metabolism
in
the
resting
human
prefrontal
cortex
can
facilitate
quantitative
metrics
unilateral
mitochondrial–hemodynamic
coupling
bilateral
connectivity
infraslow
oscillation
frequencies
young
adults.
The
includes
three
distinct
vasomotions
with
endogenic
(E),
neurogenic
(N),
myogenic
(M)
frequency
bands.
goal
this
was
to
prove
hypothesis
there
are
significant
differences
between
older
adults
(uCOP)
(bCON)
cortex.
Accordingly,
we
performed
from
24
(67.2
±
5.9
years
age)
using
same
two-channel
broadband
near-infrared
spectroscopy
(bbNIRS)
setup
resting-state
experimental
protocol
as
those
study.
After
quantification
uCOP
bCON
E/N/M
statistical
analysis,
had
significantly
weaker
hemodynamic
but
stronger
metabolic
than
M
band.
Furthermore,
exhibited
on
both
sides
all
bands,
particularly
a
very
large
effect
size
band
(>1.9).
These
age-related
results
clearly
support
our
were
well
interpreted
following
neurophysiological
principles.
key
finding
paper
is
highly
associated
age
may
have
potential
become
meaningful
features
for
brain
health
be
translatable
future
clinical
applications,
such
early
detection
Alzheimer’s
disease.
