Mobile fNIRS for exploring inter-brain synchrony across generations and time

Frontiers in Neuroergonomics, Год журнала: 2024, Номер 4

Опубликована: Янв. 2, 2024

While still relatively rare, longitudinal hyperscanning studies are exceptionally valuable for documenting changes in inter-brain synchrony, which may turn underpin how behaviors develop and evolve social settings. The generalizability ecological validity of this experimental approach hinges on the selected imaging technique being mobile–a requirement met by functional near-infrared spectroscopy (fNIRS). fNIRS has most frequently been used to examine development synchrony behavior child-parent dyads. In position paper, we contend that dedicating attention intergenerational stands benefit fields cognitive neuroscience more broadly. We argue is particularly relevant understanding neural mechanisms underpinning dynamics, potentially benchmarking progress psychological interventions, many situated contexts. line with our position, highlight areas research stand be enhanced mobile devices, describe challenges arise from measuring across generations real world, offer potential solutions.

Язык: Английский

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Introduction to the Optics and the Brain 2023 feature issue

Biomedical Optics Express, Год журнала: 2024, Номер 15(4), С. 2110 - 2110

Опубликована: Янв. 2, 2024

A feature issue is being presented by a team of guest editors containing papers based on contributed submissions including studies at Optics and the Brain, held April 24-27, 2023 as part Optica Biophotonics Congress: in Life Sciences, Vancouver, Canada.

Язык: Английский

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Lateralization of cortical activity, networks, and hemodynamic lag after stroke: A resting‐state fNIRS study

Journal of Biophotonics, Год журнала: 2024, Номер 17(7)

Опубликована: Апрель 24, 2024

Abstract Focal damage due to stroke causes widespread abnormal changes in brain function and hemispheric asymmetry. In this study, functional near‐infrared spectroscopy (fNIRS) was used collect resting‐state hemoglobin data from 85 patients with subacute 26 healthy controls, comparatively analyze the characteristics of lateralization after terms cortical activity, networks, hemodynamic lags. Higher intensity motor lower autonomy, more leads or lags were found affected hemisphere. Lateralization metrics three aspects all associated Fugl‐Meyer score. The results study prove that may provide clinical reference for rehabilitation. Meanwhile, present piloted use fNIRS analyzing lag, demonstrating potential assess abnormalities addition neurological stroke.

Язык: Английский

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Applications of Functional Near-Infrared Spectroscopy (fNIRS) Neuroimaging During Rehabilitation Following Stroke: A Review

Medical Science Monitor, Год журнала: 2024, Номер 30

Опубликована: Май 6, 2024

Stroke is a cerebrovascular disease that impairs blood supply to localized brain tissue regions due various causes.This leads ischemic and hypoxic lesions, necrosis of the tissue, variety functional disorders.Abnormal cortical activation connectivity occur in after stroke, but patterns reorganization are not well understood.Rehabilitation interventions can enhance recovery stroke patients.However, clinicians require objective measures support their practice, as outcome for based on scale scores.Furthermore, most effective rehabilitation treating patients yet be investigated.Functional near-infrared spectroscopy (fNIRS) non-invasive neuroimaging method detects changes cerebral hemodynamics during task performance.It widely used neurological research clinical practice its safety, portability, high motion tolerance, low cost.This paper briefly introduces imaging principle advantages disadvantages fNIRS summarize application post-stroke rehabilitation.

Язык: Английский

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Study on resting-state functional connectivity characteristics under hypnosis using functional near-infrared spectroscopy

Frontiers in Psychology, Год журнала: 2025, Номер 16

Опубликована: Июнь 5, 2025

Objective Numerous studies suggest that hypnosis has significant potential in mental health and cognitive disorder treatments. However, the mechanisms by which influences brain activity functional network connectivity remain unclear. This study employed near-infrared spectroscopy (fNIRS) to investigate resting-state (rsFC) under hypnosis. Methods Twenty-six healthy college students participated study. Resting-state oxygenated hemoglobin (HbO) data were collected from prefrontal cortex (PFC) during both control aware hypnotic states. Functional strengths between these states analyzed assess changes associated with deep Results A total of 55 paired samples t -tests conducted across 11 regions interest (ROIs), revealing statistically differences ( p < 0.05) strength state 10 comparisons. Increased (6 pairs): LBA9-RBA10 = −2.672, 0.013), LBA6-RBA46 −2.948, 0.007), LBA46-RBA46 −2.516, 0.019), RBA8-RBA46 −2.689, RBA9-RBA46 −2.090, 0.047), LBA10-RBA10 −2.315, 0.029); Decreased (4 LBA9-LBA45 2.064, 0.049), LBA6-LBA45 3.151, 0.004), LBA8-LBA45 2.438, 0.022), LBA8-RBA9 2.085, 0.047). No observed other ROI pairs. Conclusion Hypnosis appears modulate function DLPFC, PFC, related regions, enhancing specific connectivity. preliminary demonstrates analysis using fNIRS is a valuable approach for studying

Язык: Английский

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Effects of different frequencies music on cortical responses and functional connectivity in patients with minimal conscious state

Journal of Biophotonics, Год журнала: 2024, Номер 17(5)

Опубликована: Фев. 1, 2024

Abstract The objective of this study was to investigate brain activation and functional network patterns during musical interventions in different frequency bands using near‐infrared spectroscopy, provide a basis for more effective music therapy strategy selection patients minimally conscious state (MCS). Twenty six MCS 20 healthy people were given intervention with low (31–180 Hz), medium (180–4k high (4k–22k Hz) audio. In patients, induced left prefrontal cortex primary sensory (S1), also left‐hemisphere lateralization effect dorsolateral (DLPFC). And the connectivity right DLPFC‐right S1 significantly improved by intervention. may contribute than recovery consciousness. This validated effectiveness fNIRS studies function patients.

Язык: Английский

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Priming transcranial direct current stimulation for improving hemiparetic upper limb in patients with subacute stroke: study protocol for a randomised controlled trial

BMJ Open, Год журнала: 2024, Номер 14(2), С. e079372 - e079372

Опубликована: Фев. 1, 2024

Transcranial direct current stimulation (tDCS) is a non-invasive brain technique that modulates states by applying weak electrical to the cortex. Several studies have shown anodal of ipsilesional primary motor cortex (M1) may promote recovery affected upper limb in patients with stroke; however, high-level clinical recommendation cannot be drawn view inconsistent findings. A priming protocol has been proposed induce stable modulatory effects, which an inhibitory applied prior excitatory area. Our recent work showed theta burst magnetic demonstrated superior effects improving function and neurophysiological outcomes. However, it remains unknown whether pairing session cathodal tDCS will also capitalise on its therapeutic effects. This two-arm double-blind randomised controlled trial involving 134 1-6 months after stroke onset. Eligible participants randomly allocated receive 10 sessions tDCS+robotic training, or non-priming training for 2 weeks. The outcome Fugl-Meyer Assessment-upper extremity, secondary outcomes are Wolf Motor Function Test Modified Barthel Index. motor-evoked potentials, regional oxyhaemoglobin level resting-state functional connectivity between bilateral M1 acquired analysed investigate neuroplasticity. study approved Research Ethics Committee Shanghai Yangzhi Rehabilitation Center (reference number: Yangzhi2023-022) conducted accordance Declaration Helsinki 1964, as revised 2013. ChiCTR2300074681.

Язык: Английский

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Reliability of brain metrics derived from a Time-Domain Functional Near-Infrared Spectroscopy System

Scientific Reports, Год журнала: 2024, Номер 14(1)

Опубликована: Июль 30, 2024

With the growing interest in establishing brain-based biomarkers for precision medicine, there is a need noninvasive, scalable neuroimaging devices that yield valid and reliable metrics. Kernel's second-generation Flow2 Time-Domain Functional Near-Infrared Spectroscopy (TD-fNIRS) system meets requirements of noninvasive neuroimaging, uses validated modality to measure brain function. In this work, we investigate test-retest reliability (TRR) set metrics derived from recordings. We adopted repeated-measures design with 49 healthy participants, quantified TRR over multiple time points different headsets—in experimental conditions including resting state, sensory, cognitive task. Results demonstrated high state features hemoglobin concentrations, head tissue light attenuation, amplitude low frequency fluctuations, functional connectivity. Additionally, passive auditory Go/No-Go inhibitory control tasks each exhibited similar activation patterns across days. Notably, areas highest were regions during task, right prefrontal consistent prior literature. This study underscores Flow2-derived metrics, supporting its potential actualize vision using diagnosis, treatment selection monitoring neuropsychiatric neurocognitive disorders.

Язык: Английский

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Reliability of brain metrics derived from a Time-Domain Functional Near-Infrared Spectroscopy System

bioRxiv (Cold Spring Harbor Laboratory), Год журнала: 2024, Номер unknown

Опубликована: Март 14, 2024

Abstract With the growing interest in establishing brain-based biomarkers for precision medicine, there is a need noninvasive, scalable neuroimaging devices that yield valid and reliable metrics. Kernel’s second-generation Flow2 Time-Domain Functional Near-Infrared Spectroscopy (TD-fNIRS) system meets requirements of noninvasive neuroimaging, uses validated modality to measure brain function. In this work, we investigate test-retest reliability (TRR) set metrics derived from recordings. We adopted repeated-measures design with 49 healthy participants, quantified TRR over multiple time points different headsets—in experimental conditions including resting state, sensory, cognitive task. Results demonstrated high state features hemoglobin concentrations, head tissue light attenuation, amplitude low frequency fluctuations, functional connectivity. Additionally, passive auditory Go/No-Go inhibitory control tasks each exhibited similar activation patterns across days. Notably, areas highest were regions during task, right prefrontal consistent prior literature. This study underscores Flow2-derived metrics, supporting its potential actualize vision using diagnosis, treatment selection monitoring neuropsychiatric neurocognitive disorders.

Язык: Английский

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Altered functional connectivity in preterm neonates with intraventricular hemorrhage assessed using functional near-infrared spectroscopy

Scientific Reports, Год журнала: 2024, Номер 14(1)

Опубликована: Сен. 27, 2024

Intraventricular hemorrhage (IVH) is a common neurological injury following very preterm birth. Resting-state functional connectivity (RSFC) using magnetic resonance imaging (fMRI) associated with severity; yet, fMRI impractical for use in intensive care settings. Functional near-infrared spectroscopy (fNIRS) measures RSFC through cerebral hemodynamics and has greater bedside accessibility than fMRI. We evaluated neonates IVH fNIRS at term-equivalent age, compared between healthy newborns those IVH. Sixteen born were scanned fNIRS. Additionally, fifteen In preterms IVH, maps Euclidean Jaccard distances. The severity of relation to fNIRS-RSFC strength was examined generalized linear models. showed good correspondence. Connectivity significantly lower (p-value = 0.023) infants mild 0.026) moderate/severe potential be new tool assessing brain monitoring hemodynamics, as well promising biomarker infants.

Язык: Английский

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