Frontiers in Microbiology,
Год журнала:
2024,
Номер
15
Опубликована: Ноя. 5, 2024
The
microbiota,
intensely
intertwined
with
mammalian
physiology,
significantly
impacts
health,
productivity,
and
reproductive
functions.
normal
microbiota
interacts
the
host
through
following
key
mechanisms:
acting
as
a
protective
barrier
against
pathogens,
maintain
mucosal
integrity,
assisting
in
nutrient
metabolism,
modulating
of
immune
response.
Therefore,
supporting
growth
development
host,
providing
protection
pathogens
toxic
substances.
influences
brain
behavior,
demonstrated
by
comprehensive
findings
from
controlled
laboratory
experiments
human
clinical
studies.
prospects
suggested
that
gut
microbiome
influence
neurodevelopmental
processes,
modulate
stress
responses,
affect
cognitive
function
gut-brain
axis.
Microbiota
gastrointestinal
tract
farm
animals
break
down
ferment
ingested
feed
into
nutrients,
utilize
to
produce
meat
milk.
Among
beneficial
by-products
short-chain
fatty
acids
(SCFAs)
are
particularly
noteworthy
for
their
substantial
role
disease
prevention
promotion
various
productive
aspects
mammals.
plays
pivotal
hormonal
systems
mammals,
boosting
performance
both
sexes
fostering
maternal-infant
connection,
thereby
becoming
crucial
factor
sustaining
existence.
is
critical
influencing
success
production
traits
A
well-balanced
improves
absorption
metabolic
efficiency,
leading
better
rates,
increased
milk
production,
enhanced
overall
health.
Additionally,
it
regulates
hormones
like
estrogen
progesterone,
which
essential
successful
conception
pregnancy.
Understanding
offers
valuable
insights
optimizing
breeding
improving
outcomes,
contributing
advancements
agriculture
veterinary
medicine.
This
study
emphasizes
ecological
roles
highlighting
contributions
success.
By
integrating
perspectives,
demonstrates
how
microbial
communities
enhance
function,
regulation
across
species,
offering
benefit
agricultural
advancements.
International Journal of Molecular Sciences,
Год журнала:
2022,
Номер
23(2), С. 860 - 860
Опубликована: Янв. 13, 2022
Preterm
infants
are
at
increased
risk
for
invasive
neonatal
bacterial
infections.
S.
epidermidis,
a
ubiquitous
skin
commensal,
is
major
cause
of
late-onset
sepsis,
particularly
in
high-resource
settings.
The
vulnerability
preterm
to
serious
infections
commonly
attributed
their
distinct
and
developing
immune
system.
While
developmentally
immature
defences
play
large
role
facilitating
invasion,
this
fails
explain
why
only
subset
develop
with
low-virulence
organisms
when
exposed
similar
factors
the
ICU.
Experimental
research
has
explored
potential
virulence
mechanisms
contributing
pathogenic
shift
commensal
epidermidis
strains.
Furthermore,
comparative
genomics
studies
have
yielded
insights
into
emergence
spread
nosocomial
strains,
genetic
functional
characteristics
implicated
disease
neonates.
These
highlighted
multifactorial
nature
traits
relating
pathogenicity
commensalism.
In
review,
we
discuss
known
host
pathogen
drivers
sepsis
provide
future
perspectives
close
gap
our
understanding
as
morbidity
mortality.
Environmental Microbiology,
Год журнала:
2024,
Номер
26(2)
Опубликована: Янв. 9, 2024
Abstract
Host‐associated
microbes
influence
host
health
and
function
can
be
a
first
line
of
defence
against
infections.
While
research
increasingly
shows
that
terrestrial
plant
microbiomes
contribute
to
bacterial,
fungal,
oomycete
disease
resistance,
no
comparable
experimental
work
has
investigated
marine
or
more
diverse
agents.
We
test
the
hypothesis
eelgrass
(
Zostera
marina
)
leaf
microbiome
increases
resistance
seagrass
wasting
disease.
From
field
with
paired
diseased
asymptomatic
tissue,
16S
rRNA
gene
amplicon
sequencing
revealed
bacterial
composition
richness
varied
markedly
between
tissue
in
one
two
years.
This
suggests
on
microbial
communities
may
vary
environmental
conditions.
next
experimentally
reduced
antibiotics
bleach,
then
inoculated
plants
Labyrinthula
zosterae
,
causative
agent
detected
significantly
higher
severity
native
than
an
microbiome.
Our
results
over
multiple
experiments
do
not
support
protective
role
L.
.
Further
studies
these
host–microbe–pathogen
relationships
continue
show
new
diseases.
Frontiers in Microbiology,
Год журнала:
2024,
Номер
15
Опубликована: Ноя. 5, 2024
The
microbiota,
intensely
intertwined
with
mammalian
physiology,
significantly
impacts
health,
productivity,
and
reproductive
functions.
normal
microbiota
interacts
the
host
through
following
key
mechanisms:
acting
as
a
protective
barrier
against
pathogens,
maintain
mucosal
integrity,
assisting
in
nutrient
metabolism,
modulating
of
immune
response.
Therefore,
supporting
growth
development
host,
providing
protection
pathogens
toxic
substances.
influences
brain
behavior,
demonstrated
by
comprehensive
findings
from
controlled
laboratory
experiments
human
clinical
studies.
prospects
suggested
that
gut
microbiome
influence
neurodevelopmental
processes,
modulate
stress
responses,
affect
cognitive
function
gut-brain
axis.
Microbiota
gastrointestinal
tract
farm
animals
break
down
ferment
ingested
feed
into
nutrients,
utilize
to
produce
meat
milk.
Among
beneficial
by-products
short-chain
fatty
acids
(SCFAs)
are
particularly
noteworthy
for
their
substantial
role
disease
prevention
promotion
various
productive
aspects
mammals.
plays
pivotal
hormonal
systems
mammals,
boosting
performance
both
sexes
fostering
maternal-infant
connection,
thereby
becoming
crucial
factor
sustaining
existence.
is
critical
influencing
success
production
traits
A
well-balanced
improves
absorption
metabolic
efficiency,
leading
better
rates,
increased
milk
production,
enhanced
overall
health.
Additionally,
it
regulates
hormones
like
estrogen
progesterone,
which
essential
successful
conception
pregnancy.
Understanding
offers
valuable
insights
optimizing
breeding
improving
outcomes,
contributing
advancements
agriculture
veterinary
medicine.
This
study
emphasizes
ecological
roles
highlighting
contributions
success.
By
integrating
perspectives,
demonstrates
how
microbial
communities
enhance
function,
regulation
across
species,
offering
benefit
agricultural
advancements.
