Biomedicines,
Год журнала:
2023,
Номер
11(4), С. 1143 - 1143
Опубликована: Апрель 10, 2023
During
the
COVID-19
pandemic,
different
SARS-CoV-2
variants
of
concern
(VOC)
with
specific
characteristics
have
emerged
and
spread
worldwide.
At
same
time,
clinicians
routinely
evaluate
results
certain
blood
tests
upon
patient
admission
as
well
during
hospitalization
to
assess
disease
severity
overall
status.
In
present
study,
we
searched
for
significant
cell
count
biomarker
differences
among
patients
affected
Alpha,
Delta
Omicron
VOCs
at
admission.
Data
from
330
were
retrieved
regarding
age,
gender,
VOC,
(WBC,
Neut%,
Lymph%,
Ig%,
PLT),
common
biomarkers
(D-dimers,
urea,
creatinine,
SGOT,
SGPT,
CRP,
IL-6,
suPAR),
ICU
death.
Statistical
analyses
performed
using
ANOVA,
Kruskal-Wallis
test,
two-way
Chi-square,
T-test,
Mann-Whitney
test
logistic
regression
was
where
appropriate
SPSS
v.28
STATA
14.
Age
VOC
significantly
associated
hospitalization,
whereas
groups
found
WBC,
PLT,
D-dimers
suPAR.
Our
showed
that
throughout
current
not
only
but
also
laboratory
parameters
are
used
patient's
status
subject
changes.
Journal of Personalized Medicine,
Год журнала:
2022,
Номер
12(6), С. 995 - 995
Опубликована: Июнь 18, 2022
Over
the
two
years
that
we
have
been
experiencing
Severe
Acute
Respiratory
Syndrome
Coronavirus-2
(SARS-CoV-2)
pandemic,
our
challenges
race
to
develop
vaccines
and
difficulties
in
fighting
against
new
variants
due
rapid
ability
of
virus
evolve.
In
this
sense,
different
organizations
identified
classified
emerging,
distinguishing
between
concern
(VOC),
interest
(VOI),
or
under
monitoring
(VUM).
The
following
review
aims
describe
latest
updates
focusing
on
VOC
already
de-escalated
variants,
as
well
impact
these
had
global
situation.
Understanding
intrinsic
properties
SARS-CoV-2
its
interaction
with
immune
system
vaccination
is
essential
make
out
underlying
mechanisms
led
appearance
helping
determine
next
steps
for
better
public
management
pandemic.
Cancers,
Год журнала:
2022,
Номер
14(15), С. 3711 - 3711
Опубликована: Июль 29, 2022
The
majority
of
publications
regarding
SARS-CoV-2
infections
in
adult
patients
with
acute
leukemia
(AL)
refer
to
hematological
general
and
are
not
focused
on
myeloid
(AML)
or
lymphoblastic
(ALL).
We
herein
report
a
review
the
current
literature
AL
infected
SARS-CoV-2.
Overall,
SARS-CoV-2-associated
mortality
ranges
from
20-52%
AL.
AML
have
particularly
high
COVID-19-related
mortality.
Of
note,
most
available
data
relate
pre-vaccination
era
variants
before
Omicron.
impact
COVID-19
treatment
is
rarely
reported.
Based
few
studies
available,
delay
does
appear
be
associated
an
increased
risk
relapse,
whereas
therapy
discontinuation
was
worse
outcomes
patients.
Therefore,
recommendations
suggest
delaying
systemic
SARS-CoV-2-positive
until
negativity,
if
immediate
required.
It
recommended
offer
vaccination
all
patients;
reported
antibody
responses
around
80-96%.
Seronegative
should
additionally
receive
prophylactic
administration
anti-SARS-CoV-2
monoclonal
antibodies.
Patients
treated
early
antiviral
prevent
disease
progression
enable
rapid
elimination
virus.
Viruses,
Год журнала:
2022,
Номер
14(9), С. 1913 - 1913
Опубликована: Авг. 30, 2022
The
association
between
mean
air
temperature
and
new
SARS-CoV-2
case
numbers
throughout
the
ongoing
coronavirus
disease
2019
(COVID-19)
pandemic
was
investigated
to
identify
whether
diverse
lineages
may
exhibit
environmental
behaviors.
number
of
COVID-19
daily
cases
in
province
Verona
obtained
from
Veneto
Regional
Healthcare
Service,
whilst
during
same
period
retrieved
Agency
for
Ambient
Prevention
Protection
Veneto.
A
significant
inverse
correlation
found
up
Omicron
BA.1/BA.2
predominance
(correlation
coefficients
-0.79
-0.41).
then
became
positive
when
BA.4/BA.5
were
prevalent
(r
=
0.32).
When
median
value
(and
interquartile
range;
IQR)
recorded
warmer
year
(June-July)
compared
across
three
years
pandemic,
a
gradual
increase
could
be
seen
over
time,
1
(IQR,
0-2)
2020,
22
11-113)
2021,
890
343-1345)
2022.
These
results
suggest
that
measures
preventing
infection
should
not
completely
abandoned
periods
year.
Biomedicines,
Год журнала:
2023,
Номер
11(4), С. 1143 - 1143
Опубликована: Апрель 10, 2023
During
the
COVID-19
pandemic,
different
SARS-CoV-2
variants
of
concern
(VOC)
with
specific
characteristics
have
emerged
and
spread
worldwide.
At
same
time,
clinicians
routinely
evaluate
results
certain
blood
tests
upon
patient
admission
as
well
during
hospitalization
to
assess
disease
severity
overall
status.
In
present
study,
we
searched
for
significant
cell
count
biomarker
differences
among
patients
affected
Alpha,
Delta
Omicron
VOCs
at
admission.
Data
from
330
were
retrieved
regarding
age,
gender,
VOC,
(WBC,
Neut%,
Lymph%,
Ig%,
PLT),
common
biomarkers
(D-dimers,
urea,
creatinine,
SGOT,
SGPT,
CRP,
IL-6,
suPAR),
ICU
death.
Statistical
analyses
performed
using
ANOVA,
Kruskal-Wallis
test,
two-way
Chi-square,
T-test,
Mann-Whitney
test
logistic
regression
was
where
appropriate
SPSS
v.28
STATA
14.
Age
VOC
significantly
associated
hospitalization,
whereas
groups
found
WBC,
PLT,
D-dimers
suPAR.
Our
showed
that
throughout
current
not
only
but
also
laboratory
parameters
are
used
patient's
status
subject
changes.
