Neural oscillations are a start toward understanding brain activity rather than the end

PLoS Biology, Год журнала: 2021, Номер 19(5), С. e3001234 - e3001234

Опубликована: Май 4, 2021

Does rhythmic neural activity merely echo the features of environment, or does it reflect a fundamental computational mechanism brain? This debate has generated series clever experimental studies attempting to find an answer. Here, we argue that field been obstructed by predictions oscillators are based more on intuition rather than biophysical models compatible with observed phenomena. What follows is cautionary examples serve as reminders ground our hypotheses in well-developed theories oscillatory behavior put forth theoretical study dynamical systems. Ultimately, hope this exercise will push concern itself less vague question "oscillation not" and specific can be readily tested.

Язык: Английский

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Multisensory flicker modulates widespread brain networks and reduces interictal epileptiform discharges

Nature Communications, Год журнала: 2024, Номер 15(1)

Опубликована: Апрель 11, 2024

Modulating brain oscillations has strong therapeutic potential. Interventions that both non-invasively modulate deep structures and are practical for chronic daily home use desirable a variety of applications. Repetitive audio-visual stimulation, or sensory flicker, is an accessible approach modulates hippocampus in mice, but its effects humans poorly defined. We therefore quantified the neurophysiological flicker with high spatiotemporal resolution patients focal epilepsy who underwent intracranial seizure monitoring. In this interventional trial (NCT04188834) cross-over design, subjects different frequencies stimulation same recording session effect exposure on local field potential (LFP) power interictal epileptiform discharges (IEDs) as primary secondary outcomes, respectively. Flicker focally modulated potentials expected canonical cortices also medial temporal lobe prefrontal cortex, likely via resonance stimulated long-range circuits. Moreover, decreased discharges, pathological biomarker degenerative diseases, most strongly regions where were flicker-modulated, especially visual cortex lobe. This met scientific goal now closed. Our findings reveal how multi-sensory may cortical to mitigate activity humans.

Язык: Английский

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The psychophysiology of music-based interventions and the experience of pain

Frontiers in Psychology, Год журнала: 2024, Номер 15

Опубликована: Май 10, 2024

In modern times there is increasing acceptance that music-based interventions are useful aids in the clinical treatment of a range neurological and psychiatric conditions, including helping to reduce perception pain. Indeed, belief music, whether listening or performing, can alter human pain experiences has long history, dating back ancient Greeks, its potential healing properties have been appreciated by indigenous cultures around world. The subjective experience acute chronic complex, influenced many intersecting physiological psychological factors, it therefore be expected impact music therapy on may vary from one situation another, person another. Where persists becomes chronic, aberrant central processing key feature associated with ongoing experience. Nonetheless, beneficial effects exposure relief reported across wide shown effective neonates, children adults. this comprehensive review we examine various neurochemical, factors underpin experience, potentially operate at levels – periphery, spinal cord, brainstem, limbic system multiple areas cerebral cortex. We discuss extent which these individually combination, influence how affects both quality intensity pain, noting remains controversy about respective roles diverse peripheral processes play Better understanding mechanisms underlie music’s together insights into should aid developing more synergistic approaches when combined treatments. ubiquitous nature also facilitates application therapeutic environment daily life, for individual social benefit.

Язык: Английский

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Challenges and Approaches in the Study of Neural Entrainment

Journal of Neuroscience, Год журнала: 2024, Номер 44(40), С. e1234242024 - e1234242024

Опубликована: Окт. 2, 2024

When exposed to rhythmic stimulation, the human brain displays activity across sensory modalities and regions. Given ubiquity of this phenomenon, how rhythms are transformed into neural remains surprisingly inconclusive. An influential model posits that endogenous oscillations entrain external rhythms, thereby encoding environmental dynamics shaping perception. However, research on entrainment faces multiple challenges, from ambiguous definitions methodological difficulties when need be identified disentangled other stimulus-related mechanisms can lead similar phase-locked responses. Yet, recent years have seen novel approaches overcome these including computational modeling, insights dynamical systems theory, sophisticated stimulus designs, study neuropsychological impairments. This review outlines key challenges in research, delineates state-of-the-art approaches, integrates findings animal neurophysiology provide a broad perspective usefulness, validity, constraints oscillatory models brain-environment interaction.

Язык: Английский

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A Silent Disco: Differential Effects of Beat-based and Pattern-based Temporal Expectations on Persistent Entrainment of Low-frequency Neural Oscillations

Journal of Cognitive Neuroscience, Год журнала: 2023, Номер 35(6), С. 990 - 1020

Опубликована: Янв. 1, 2023

The brain uses temporal structure in the environment, like rhythm music and speech, to predict timing of events, thereby optimizing their processing perception. Temporal expectations can be grounded different aspects input structure, such as a regular beat or predictable pattern. One influential account posits that generic mechanism underlies beat-based pattern-based expectations, namely, entrainment low-frequency neural oscillations rhythmic input, whereas other accounts assume underlying mechanisms. Here, we addressed this outstanding issue by examining EEG activity behavioral responses during silent periods following auditory sequences. We measured outlasting rhythms both avoid confounding analyses with evoked responses, directly test whether persist beyond stimulation, predicted theories. To properly disentangle which often occur simultaneously, used non-isochronous beat, pattern, random timing. In Experiment 1 (n = 32), affected ratings probe events for two beat-cycles after end rhythm. effects reflected one interval. 2 27), using EEG, found enhanced spectral power at frequency sequences listening silence. For sequences, pattern-specific was present listening, but not Moreover, difference signal Finally, show how multivariate pattern decoding multiscale entropy-measures sensitive non-oscillatory components signal-can expectations. Together, our results suggest form may affect associated climbing differentially

Язык: Английский

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The power of rhythms: how steady-state evoked responses reveal early neurocognitive development

NeuroImage, Год журнала: 2022, Номер 254, С. 119150 - 119150

Опубликована: Март 26, 2022

Electroencephalography (EEG) is a non-invasive and painless recording of cerebral activity, particularly well-suited for studying young infants, allowing the inspection responses in constellation different ways. Of particular interest developmental cognitive neuroscientists use rhythmic stimulation, analysis steady-state evoked potentials (SS-EPs) – an approach also known as frequency tagging. In this paper we rely on existing SS-EP early literature to illustrate important advantages SS-EPs developing brain. We argue that (1) technique both objective predictive: response expected at stimulation (and/or higher harmonics), (2) its high spectral specificity makes computed robust artifacts, (3) allows short efficient recordings, compatible with infants' limited attentional spans. additionally provide overview some recent inspiring adult research, order (4) can be implemented creatively target wide range neural processes. For all these reasons, expect play increasing role understanding Finally, practical guidelines implementing analyzing studies.

Язык: Английский

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Challenges and new perspectives of developmental cognitive EEG studies

NeuroImage, Год журнала: 2022, Номер 260, С. 119508 - 119508

Опубликована: Июль 23, 2022

Despite shared procedures with adults, electroencephalography (EEG) in early development presents many specificities that need to be considered for good quality data collection. In this paper, we provide an overview of the most representative cognitive developmental EEG studies focusing on neuroimaging technique young participants, such as attrition and artifacts. We also summarize results research obtained time time-frequency domains use more advanced signal processing methods. Finally, briefly introduce three recent standardized pipelines will help promote replicability comparability across experiments ages. While paper does not claim exhaustive, it aims give a sufficiently large challenges solutions available conduct robust studies.

Язык: Английский

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From Perception to Pleasure

Oxford University Press eBooks, Год журнала: 2023, Номер unknown

Опубликована: Ноя. 23, 2023

Abstract How does perception of abstract tonal patterns—music—lead to the pleasure we experience from these sounds? The answer presented in this book is that music arises interactions between cortical loops enable processing sound patterns and subcortical circuits responsible for reward valuation. auditory cortex its ventral-stream connections encode acoustical features their relationships, maintain them working memory, form internal representations statistical which predictions are made about how evolve time. Disruption pathway leads amusia. dorsal stream allows sensory-motor transformations, production, metrical representation, leading when events will occur. These predictive processes play a central role creating expectancies musical transmitted dopaminergic system, where hedonic responses generated according well an event fits with predictions. linked balance predictability surprise patterns. perceptual systems anhedonia. Engagement system also related movement vocal cues, social factors, preference, emotion regulation.

Язык: Английский

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Oscillatory entrainment to our early social or physical environment and the emergence of volitional control

Developmental Cognitive Neuroscience, Год журнала: 2022, Номер 54, С. 101102 - 101102

Опубликована: Март 25, 2022

An individual's early interactions with their environment are thought to be largely passive; through the years, capacity for volitional control develops. Here, we consider: how is emergence of characterised by changes in entrainment observed between internal activity (behaviour, physiology and brain activity) sights sounds our everyday (physical social)? We differentiate contingent responsiveness (entrainment driven evoked responses external events) oscillatory (driven oscillators becoming temporally aligned oscillators). conclude that ample evidence suggests children show behavioural, physiological neural physical social environment, irrespective attention control; however, beyond currently lacking. Evidence over developmental time also Finally, suggest a mechanism which periodic environmental rhythms might facilitate both sensory processing development even absence entrainment.

Язык: Английский

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It Takes Two: Interpersonal Neural Synchrony Is Increased after Musical Interaction

Brain Sciences, Год журнала: 2022, Номер 12(3), С. 409 - 409

Опубликована: Март 20, 2022

Music's deeply interpersonal nature suggests that music-derived neuroplasticity relates to temporal dynamics, or synchrony. Interpersonal neural synchrony (INS) has been found correlate with increased behavioral during social interactions and may represent mechanisms support them. As often do not have clearly delineated boundaries, many start stop intermittently, we hypothesize a signature of INS be detectable following an interaction. The present study aimed investigate this hypothesis using pre-post paradigm, measuring interbrain phase coherence before after cooperative dyadic musical Ten dyads underwent synchronous electroencephalographic (EEG) recording silent, non-interactive periods interaction in the form tapping game. Significant post-interaction increases delta band were post-condition positively correlated duration preceding These findings suggest mechanism by which efficiently continued interruption hold potential for neuroplastic adaption longitudinal studies. also idea represents active maintaining rather than mere parallel processing stimuli motor activity.

Язык: Английский

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