PLoS Pathogens,
Год журнала:
2024,
Номер
20(1), С. e1011947 - e1011947
Опубликована: Янв. 17, 2024
Microbes
associated
with
an
organism
can
significantly
modulate
its
susceptibility
to
viral
infections,
but
our
understanding
of
the
influence
individual
microbes
remains
limited.
The
nematode
Caenorhabditis
elegans
is
a
model
that
in
nature
inhabits
environments
rich
bacteria.
Here,
we
examine
impact
71
naturally
bacteria
on
C
.
only
known
natural
virus,
Orsay
virus.
Our
findings
reveal
infection
influenced
by
monobacterial
environments.
Compared
Escherichia
coli
environmental
reference,
majority
tested
reduced
infection.
This
reduction
not
caused
virion
degradation
or
poor
animal
nutrition
repression
bacterial
strains
Chryseobacterium
JUb44
and
Sphingobacterium
BIGb0172
does
require
RIG-I
homolog
DRH-1,
which
activate
antiviral
responses
such
as
RNA
interference
transcriptional
regulation.
research
highlights
necessity
considering
biotic
studies
opens
way
future
host-microbe-virus
interactions.
Functional Ecology,
Год журнала:
2019,
Номер
34(3), С. 550 - 560
Опубликована: Ноя. 26, 2019
Abstract
Microplastic
pollution
is
a
topic
of
increasing
concern
for
the
world's
oceans,
freshwaters
and,
most
recently,
soils.
Microplastics
have
been
found
in
soils
across
globe.
Like
other
anthropogenic
pollutants,
they
can
negatively
affect
range
soil
organisms
through
several
mechanisms,
though
often
dependent
on
particle
size,
shape
and
polymer
type.
However,
microplastics
are
unique
among
pollutants
due
to
diversity
ways
which
may
themselves
be
able
their
occurrence
distribution
mediate
effects
rest
food
web.
In
this
review,
we
argue
more
explicitly
ecological
framing
novel
issue
environment
discuss
potential
interactions
with
communities,
including
microplastic
formation
via
microbial
faunal
fragmentation
large
plastic
debris
such
as
earthworms
placing
particles
pedological
contexts
could
not
otherwise
reach.
Ecological
crucial
dictating
microplastics’
ultimate
fate
effect
terrestrial
ecosystems.
A
free
Plain
Language
Summary
within
Supporting
Information
article.
Evolution Letters,
Год журнала:
2019,
Номер
3(2), С. 217 - 236
Опубликована: Апрель 1, 2019
The
nematode
Caenorhabditis
elegans
has
been
central
to
the
understanding
of
metazoan
biology.
However,
C.
is
but
one
species
among
millions
and
significance
this
important
model
organism
will
only
be
fully
revealed
if
it
placed
in
a
rich
evolutionary
context.
Global
sampling
efforts
have
led
discovery
over
50
putative
from
genus
Caenorhabditis,
many
which
await
formal
description.
Here,
we
present
descriptions
for
10
new
species.
We
also
draft
genome
sequences
nine
these
species,
along
with
transcriptome
assembly
one.
exploit
whole-genome
data
reconstruct
phylogeny
use
phylogenetic
tree
dissect
evolution
morphology
genus.
reveal
extensive
variation
size
investigate
molecular
processes
that
underlie
variation.
show
unexpected
complexity
history
key
developmental
pathway
genes.
These
associated
genomic
resources
essential
our
attempts
understand
origins
model.
Genetics,
Год журнала:
2019,
Номер
213(4), С. 1145 - 1188
Опубликована: Дек. 1, 2019
Stem
cell
systems
regulate
tissue
development
and
maintenance.
The
germline
stem
system
is
essential
for
animal
reproduction,
controlling
both
the
timing
number
of
progeny
through
its
influence
on
gamete
production.
In
this
review,
we
first
draw
general
comparisons
to
in
other
organisms,
then
present
our
current
understanding
Hawaiian
isolates
of
the
nematode
species
Caenorhabditis
elegans
have
long
been
known
to
harbor
genetic
diversity
greater
than
rest
worldwide
population,
but
this
observation
was
supported
by
only
a
small
number
wild
strains.
To
better
characterize
niche
and
C.
other
species,
we
sampled
different
substrates
niches
across
islands.
We
identified
hundreds
new
strains
from
oiwi.
are
found
in
cooler
climates
at
high
elevations
not
associated
with
any
specific
substrate,
as
compared
species.
Surprisingly,
admixture
analysis
revealed
evidence
shared
ancestry
between
some
non-Hawaiian
suggest
that
deep
observed
Hawaii
might
represent
patterns
ancestral
before
human
influence.
Genetics,
Год журнала:
2019,
Номер
212(1), С. 25 - 51
Опубликована: Март 11, 2019
Abstract
Caenorhabditis
elegans
lives
in
a
complex
habitat
which
they
routinely
experience
large
fluctuations
temperature,
and
encounter
physical
obstacles
that
vary
size
composition.
Their
is
shared
by
other
nematodes,
beneficial
harmful
bacteria,
nematode-trapping
fungi.
Not
surprisingly,
these
nematodes
can
detect
discriminate
among
diverse
environmental
cues,
exhibit
sensory-evoked
behaviors
are
readily
quantifiable
the
laboratory
at
high
resolution.
ability
to
perform
depends
on
<100
sensory
neurons,
this
compact
nervous
system
together
with
powerful
molecular
genetic
tools
has
allowed
individual
neuron
types
be
linked
specific
responses.
Here,
we
describe
neurons
molecules
enable
C.
sense
respond
stimuli.
We
focus
primarily
pathways
allow
sensation
of
mechanical
thermal
stimuli,
briefly
consider
animal’s
magnetic
electrical
fields,
light,
relative
humidity.
As
study
transduction
critically
dependent
upon
techniques
for
stimulus
delivery,
also
include
section
appropriate
methods
such
studies.
This
chapter
summarizes
current
knowledge
about
sensitivity
response
dynamics
classes
mechano-
thermosensory
from
vivo
calcium
imaging
whole-cell
patch-clamp
electrophysiology
roles
conserved
signaling
mediating
remarkably
sensitive
responses
cues.
These
studies
have
shown
protein
partners
form
mechanotransduction
channels
drawn
multiple
superfamilies
ion
channel
proteins,
signal
responsible
temperature
sensing
share
many
features
those
phototransduction
vertebrates.
