Springer eBooks, Год журнала: 2015, Номер unknown, С. 1 - 21
Опубликована: Янв. 1, 2015
Язык: Английский
Springer eBooks, Год журнала: 2015, Номер unknown, С. 1 - 21
Опубликована: Янв. 1, 2015
Язык: Английский
European Archives of Oto-Rhino-Laryngology, Год журнала: 2016, Номер 273(10), С. 3385 - 3391
Опубликована: Март 7, 2016
Язык: Английский
Процитировано
30Training and Education in Professional Psychology, Год журнала: 2017, Номер 11(2), С. 108 - 114
Опубликована: Март 23, 2017
Язык: Английский
Процитировано
28International Neuropsychiatric Disease Journal, Год журнала: 2014, Номер 2(5), С. 214 - 233
Опубликована: Янв. 10, 2014
Aim s:To review the relevant literature on Quality of Life (QOL) impairment in PTSD and impact treatment interventions QOL. Methods: A database search from 1980-2012 was conducted using Medline, PsycINFO, PILOTS keywords: �PTSD �, �posttraumatic stress disorder
Язык: Английский
Процитировано
25Biomedicines, Год журнала: 2022, Номер 10(5), С. 1107 - 1107
Опубликована: Май 10, 2022
Posttraumatic stress disorder (PTSD) is a chronic and multifactorial with prevalence ranging between 6-10% in the general population ~35% individuals high lifetime trauma exposure. Growing evidence indicates that immune system may contribute to etiology of PTSD, suggesting inflammatory dysregulation as hallmark feature PTSD. However, potential interplay central peripheral system, well biological mechanisms underlying this remain poorly understood. The activation HPA axis after exposure subsequent mediated by glucocorticoids most common mechanism orchestrates an exacerbated immunological response Recent high-throughput analyses brain tissue from both humans animal models PTSD have found changes gene regulation via epigenetic alterations participate impaired signaling goal review assess role across species, particular focus on genomics, transcriptomics, epigenomics, proteomics domains. We conducted integrative multi-omics approach identifying TNF (Tumor Necrosis Factor) signaling, interleukins, chemokines, Toll-like receptors among dysregulated pathways systems propose novel drug targets for treatment.
Язык: Английский
Процитировано
13Psycho-Oncology, Год журнала: 2019, Номер 28(5), С. 970 - 979
Опубликована: Март 8, 2019
Cancer has been reported to trigger symptoms of post-traumatic stress disorder (PTSD) in a substantial proportion individuals. Despite the significant burden associated with these symptoms, there are as yet no therapeutic guidelines. This systematic review aims evaluate effectiveness interventions for cancer-related order provide an evidence base developing appropriate clinical practice.Databases searched until April 2018 included Psych INFO, EMBASE, Medline, and Cumulative Index Nursing Allied Health Literature (CINAHL). No restrictions study design were applied. Participants aged 18 years or older who received their cancer diagnosis adulthood had PTSD included. Because heterogeneity, meta-analysis was not performed.Of 508 unique titles, eight studies met inclusion criteria: five randomised controlled trials (RCTs), one before-and-after study, case series, study. Interventions predominately psychological administered patients range types. Eye movement desensitisation reprocessing cognitive behavioural therapy-based reduced symptomatology; however, overall methodological quality limitations.At present, is only weak available reducing PTSD. The majority all regardless whether they showed pretreatment levels stress. Future would be better targeted towards have symptoms. Higher also needed before treatment recommendations can made.
Язык: Английский
Процитировано
21Springer eBooks, Год журнала: 2016, Номер unknown, С. 511 - 531
Опубликована: Янв. 1, 2016
Язык: Английский
Процитировано
21Progress in Transplantation, Год журнала: 2017, Номер 28(1), С. 70 - 76
Опубликована: Дек. 15, 2017
Objective: A high prevalence of posttraumatic stress disorder (PTSD) symptoms among transplant recipients has been associated with a low adherence to treatment and poor survival. It is crucial detect prevent the development in settings. Methods: We examined 3 liver by means Essen Trauma Inventory (ETI), self-report questionnaire. The Short Form-36 was used assess perceived health-related quality life. Patients were asked indicate most traumatic events within context transplantation procedure. Results: Five patients (4.9%) fulfilled criteria for PTSD related disease or (ETI score greater than 27). In these patients, diagnosis confirmed structured clinical interview. Fourteen (13.6%) had partial ETI less 27 16. Posttraumatic significantly physical mental reported that physicians’ disclosure experienced as traumatic, followed an intensive care unit itself. Conclusions: resulted rates comparable previous studies Medical professionals requested additional training how deliver severe diagnoses patients.
Язык: Английский
Процитировано
19PLoS ONE, Год журнала: 2014, Номер 9(10), С. e110529 - e110529
Опубликована: Окт. 23, 2014
Objective The purpose of this study was to evaluate whether individuals consider their HCV infection be a potentially traumatic experience. Additionally, we investigated its association with Post-Traumatic Stress Disorder (PTSD) and the impact PTSD diagnosis on health-related quality life (HRQoL) in infected subjects. Methods We conducted cross-sectional survey 127 HCV-infected outpatients recruited at University Hospital Salvador, Brazil. All subjects answered an orally-administered questionnaire gather clinical socio-demographic data. experiences subject's perception disease using Trauma History Questionnaire. other psychiatric diagnoses were assessed through Mini International Neuropsychiatric Interview-Brazilian Version 5.0.0 (M.I.N.I. PLUS). HRQoL Short-Form 36 (SF-36). Results Approximately 38.6% patients considered hepatitis C Of these, 60.7% had diagnosis. associated significant impairment for seven SF-36 domains as shown bymultivariate analysis: Role-Physical (β: −24.85; 95% CI: −42.08; −7.61), Bodily Pain −19.36; −31.28; −7.45), General Health −20.79; −29.65; −11.92), Vitality −11.92; −20.74; −3.1), Social Functioning −34.73; −46.79; −22.68), Role-Emotional −26.07; −44.61; −7.53), Mental −17.46; −24.38; −10.54). Conclusion is frequently experience it strongly significantly impaired HRQoL.
Язык: Английский
Процитировано
17Journal of Asthma, Год журнала: 2016, Номер 54(7), С. 723 - 731
Опубликована: Дек. 1, 2016
Using data from a cohort of World Trade Center (WTC) rescue and recovery workers with asthma, we assessed whether meeting criteria for post-traumatic stress disorder (PTSD), sub-threshold PTSD, specific PTSD symptom dimensions are associated increased asthma morbidity.
Язык: Английский
Процитировано
16International Journal of COPD, Год журнала: 2015, Номер unknown, С. 2219 - 2219
Опубликована: Окт. 1, 2015
Background: Several studies have reported on the co-occurrence of chronic obstructive pulmonary disease (COPD) and psychiatric conditions, with most robust evidence base demonstrating an impact comorbid anxiety depression COPD-related outcomes. In recent years, research has sought to determine if there is a between COPD posttraumatic stress disorder (PTSD) as well for associations PTSD To date, been no published reviews summarizing this emerging literature. Objectives: The primary objective review was adequate support COPD. Secondary objectives were to: 1) are important clinical considerations regarding management, 2) identify targeted areas further research. Methods: A structured performed using systematic search strategy limited in English, addressing adults, articles that examined: be included, must addressed some type nonreversible lung pathology. Results: total 598 identified initial review. Upon applying inclusion exclusion criteria, n=19 or abstracts our stated objectives. Overall, inconclusive Studies finding significant generally had inferior methods identifying COPD; contrast, utilized more measures (such physician exam) failed find relationship. Among examined outcomes, consistent affects perception respiratory symptom burden management. addition, measuring confounder (smoking) lacking. Conclusion: There PTSD. stronger implicating comorbidity impacting Further needed whether not likely comorbid, elucidate mechanisms connecting Keywords: disease, nonproductive cough, WTC cough syndrome, disorder, Veterans
Язык: Английский
Процитировано
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