Frontiers in Bioengineering and Biotechnology,
Год журнала:
2019,
Номер
7
Опубликована: Ноя. 8, 2019
Organophosphate
compounds
are
ubiquitously
employed
as
agricultural
pesticides
and
maintained
chemical
warfare
agents
by
several
nations.
These
highly
toxic,
show
environmental
persistence
accumulation,
contribute
to
numerous
cases
of
poisoning
death
each
year.
While
their
use
weapons
mass
destruction
is
rare,
these
never
fully
disappear
into
obscurity
they
continue
be
tools
fear
control
governments
terrorist
organizations.
Beyond
weaponization,
wide-scale
dissemination
products
has
led
accumulation
intoxication
soil
water
across
the
globe.
Therefore,
there
a
dire
need
for
rapid
safe
bioremediation,
personal
decontamination,
therapeutic
detoxicants.
hydrolyzing
enzymes
emerging
appealing
targets
satisfy
decontamination
needs
owing
ability
hydrolyze
both
nerve
using
biologically-derived
materials
environment
individual.
As
release
genetically
modified
organisms
not
widely
accepted
practice,
researchers
exploring
alternative
strategies
organophosphate
bioremediation
that
focus
on
cell-free
enzyme
systems.
In
this
review,
we
first
discuss
more
prevalent
organophosphorus
along
with
research
engineering
efforts
have
an
enhancement
in
activity,
substrate
tolerance,
stability.
later
half
advances
achieved
through
focusing
enhancing
catalytic
activity
stability
phosphotriesterase,
model
hydrolase,
various
approaches
such
nanoparticle
display,
DNA
scaffolding,
outer
membrane
vesicle
encapsulation.
Environmental
problems
have
always
received
immense
attention
from
scientists.
Toxicants
pollution
is
a
critical
environmental
concern
that
has
posed
serious
threats
to
human
health
and
agricultural
production.
Heavy
metals
pesticides
are
top
of
the
list
toxicants
endangering
nature.
This
review
focuses
on
toxic
effect
heavy
(cadmium
(Cd),
lead
(Pb),
copper
(Cu),
zinc
(Zn))
(insecticides,
herbicides,
fungicides)
adversely
influencing
ecosystem
(plant
soil)
health.
Furthermore,
accumulation
pesticide
residues
in
soils
plants
been
discussed
detail.
In
addition,
characteristics
contaminated
soil
plant
physiological
parameters
reviewed.
Moreover,
diseases
caused
by
exposure
were
also
reported.
The
bioaccumulation,
mechanism
action,
transmission
pathways
both
emphasized.
bioavailability
uptake
these
contaminants
considered.
Meanwhile,
synergistic
antagonistic
interactions
between
their
combined
effects
discussed.
Previous
relevant
studies
included
cover
all
aspects
this
review.
information
provides
deep
insights
into
understanding
hazardous
effects.
International Journal of Environmental Research and Public Health,
Год журнала:
2021,
Номер
18(2), С. 468 - 468
Опубликована: Янв. 8, 2021
The
ubiquitous
problem
of
pesticide
in
aquatic
environment
are
receiving
worldwide
concern
as
tends
to
accumulate
the
body
organism
and
sediment
soil,
posing
health
risks
human.
Many
formulations
had
introduced
due
rapid
growth
global
market
result
from
wide
use
pesticides
agricultural
non-agricultural
sectors.
occurrence
water
is
derived
by
runoff
field
industrial
wastewater.
Soluble
were
carried
away
molecules
especially
during
precipitation
event
percolating
downward
into
soil
layers
eventually
reach
surface
waters
groundwater.
Consequently,
it
degrades
quality
reduces
supply
clean
for
potable
water.
Long-time
exposure
low
concentration
resulted
non-carcinogenic
risks.
conventional
method
treatment
processes
encompasses
coagulation-flocculation,
adsorption,
filtration
sedimentation,
which
rely
on
phase
transfer
pollutants.
Those
methods
often
incurred
with
a
relatively
high
operational
cost
may
cause
secondary
pollution
such
sludge
formation.
Advanced
oxidation
(AOPs)
recognized
technologies
containing
recalcitrant
bio-refractory
pollutants
pesticides.
It
has
been
adopted
recent
purification
technology
because
thermodynamic
viability
broad
spectrum
applicability.
This
work
provides
comprehensive
review
drinking
its
possible
treatment.
Toxicology Reports,
Год журнала:
2021,
Номер
8, С. 1179 - 1192
Опубликована: Янв. 1, 2021
Pesticides
are
commonly
used
in
agriculture
to
enhance
crop
production
and
control
pests.
Therefore,
pesticide
residues
can
persist
the
environment
agricultural
crops.
Although
modern
formulations
relatively
safe
non-target
species,
numerous
theoretical
experimental
data
demonstrate
that
produce
long-term
negative
effects
on
health
of
humans
animals
stability
ecosystems.
Of
particular
interest
molecular
mechanisms
mediate
start
a
cascade
adverse
effects.
This
is
review
latest
literature
consequences
contamination
crops
by
residues.
In
addition,
we
address
issue
implicit
risks
associated
with
formulations.
The
pesticides
considered
context
Adverse
Outcome
Pathway
concept.
Veterinary Sciences,
Год журнала:
2020,
Номер
7(4), С. 166 - 166
Опубликована: Окт. 30, 2020
The
Western
honey
bee
(Apis
mellifera
L.,
Hymenoptera:
Apidae)
is
a
species
of
crucial
economic,
agricultural
and
environmental
importance.
In
the
last
ten
years,
some
regions
world
have
suffered
from
significant
reduction
colonies.
fact,
losses
are
not
an
unusual
phenomenon,
but
in
many
countries
worldwide
there
has
been
notable
decrease
cases
USA,
European
countries,
Middle
East
received
considerable
attention,
mostly
due
to
absence
easily
identifiable
cause.
It
difficult
determine
main
factors
leading
colony
because
bees’
diverse
social
behavior.
Moreover,
their
daily
routine,
they
make
contact
with
agents
environment
exposed
plethora
human
activities
consequences.
Nevertheless,
various
considered
be
contributing
losses,
recent
investigations
established
most
important
ones,
particular,
pests
diseases,
management,
including
keeping
practices
breeding,
change
climatic
conditions,
practices,
use
pesticides.
global
picture
highlights
ectoparasitic
mite
Varroa
destructor
as
major
factor
loss.
Last
least,
microsporidian
parasites,
mainly
Nosema
ceranae,
also
contribute
problem.
Thus,
it
obvious
that
affecting
globally.
Increased
monitoring
scientific
research
should
throw
new
light
on
involved
losses.
present
review
focuses
which
found
impact
increase
Agriculture,
Год журнала:
2022,
Номер
12(5), С. 600 - 600
Опубликована: Апрель 24, 2022
Pest
management
is
being
confronted
with
immense
economic
and
environmental
issues
worldwide
because
of
massive
utilization
over-reliance
on
pesticides.
The
non-target
toxicity,
residual
consequence,
challenging
biodegradability
these
synthetic
pesticides
have
become
a
serious
concern,
which
urgently
requires
the
alternative
prompt
adoption
sustainable
cost-effective
pest
control
measures.
Increasing
attention
in
safety
has
triggered
interest
approaches
through
eco-friendly
plant-based
Botanical
pesticidal
constituents
are
effective
against
myriads
destructive
pests
diseases.
More
importantly,
they
widely
available,
inexpensive,
accessible,
rapidly
biodegradable,
little
toxicity
to
beneficiary
agents.
phytochemical
compositions
diverse
plant
species
responsible
for
their
varying
mechanisms
action
However,
difficulties
formulation
insufficient
appropriate
chemical
data
led
low
level
acceptance
globally.
Therefore,
review
seeks
highlight
status,
compositions,
insecticidal
mechanisms,
challenges
pesticide
usage
agricultural
production.
Frontiers in Endocrinology,
Год журнала:
2019,
Номер
10
Опубликована: Дек. 9, 2019
Plant
Protection
Products,
more
commonly
referred
to
as
pesticides
and
biocides,
are
used
control
a
wide
range
of
yield-reducing
pests
including
insects,
fungi,
nematodes,
weeds.
Concern
has
been
raised
that
some
may
act
endocrine
disrupting
chemicals
(EDCs)
with
the
potential
interfere
hormone
systems
non-target
invertebrates
vertebrates,
humans.
EDCs
at
low
doses
particularly
vulnerable
periods
exposure
include
pre-
perinatal
development.
Of
critical
concern
is
number
developing
nervous
system
brain,
notably
thyroid
signaling.
Across
orchestrates
metamorphosis,
brain
development,
metabolism.
Pesticide
action
on
homeostasis
can
involve
interference
TH
production
its
control,
displacement
from
distributor
proteins
liver
Here
we
focused
endpoints
for
each
different
classes
reviewing
epidemiological
experimental
studies
carried
out
both
in
vivo
vitro.
We
conclude
first,
many
were
placed
market
insufficient
testing,
other
than
acute
or
chronic
toxicity,
second,
thyroid-specific
neurodevelopmental
effects
mixture
assessment
largely
absent
regulatory
directives.